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Items: 1 to 20 of 31

  • Filters activated: Toxicology. Clear all to show 72 items.
1.

Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products.

Ozaki H, Sugihara K, Watanabe Y, Ohta S, Kitamura S.

J Toxicol Sci. 2016;41(4):551-60. doi: 10.2131/jts.41.551.

2.

Ordered chimerogenesis applied to CYP2B P450 enzymes.

Lautier T, Urban P, Loeper J, Jezequel L, Pompon D, Truan G.

Biochim Biophys Acta. 2016 Jul;1860(7):1395-403. doi: 10.1016/j.bbagen.2016.03.028. Epub 2016 Mar 23.

PMID:
27015760
3.

Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes.

Jang HH, Liu J, Lee GY, Halpert JR, Wilderman PR.

Arch Biochem Biophys. 2015 Oct 15;584:61-9. doi: 10.1016/j.abb.2015.08.007. Epub 2015 Aug 28.

4.

Inhibition of cytochrome P450 2B4 by environmentally persistent free radical-containing particulate matter.

Reed JR, dela Cruz AL, Lomnicki SM, Backes WL.

Biochem Pharmacol. 2015 May 15;95(2):126-32. doi: 10.1016/j.bcp.2015.03.012. Epub 2015 Mar 24.

5.

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.

Du K, Williams CD, McGill MR, Xie Y, Farhood A, Vinken M, Jaeschke H.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):484-91. doi: 10.1016/j.taap.2013.09.010. Epub 2013 Sep 23.

6.

Induction of cytochrome P450 enzymes in primary equine hepatocyte culture.

Stefanski A, Mevissen M, Möller AM, Kuehni-Boghenbor K, Schmitz A.

Toxicol In Vitro. 2013 Oct;27(7):2023-30. doi: 10.1016/j.tiv.2013.07.009. Epub 2013 Aug 1.

PMID:
23916975
7.

Characterization of inhibitory effects of perfluorooctane sulfonate on human hepatic cytochrome P450 isoenzymes: focusing on CYP2A6.

Narimatsu S, Nakanishi R, Hanioka N, Saito K, Kataoka H.

Chem Biol Interact. 2011 Nov 15;194(2-3):120-6. doi: 10.1016/j.cbi.2011.09.002. Epub 2011 Sep 19.

PMID:
21964418
8.
9.

Nanosilver particle effects on drug metabolism in vitro.

Lamb JG, Hathaway LB, Munger MA, Raucy JL, Franklin MR.

Drug Metab Dispos. 2010 Dec;38(12):2246-51. doi: 10.1124/dmd.110.035238. Epub 2010 Sep 22.

10.

Long-term cultivation of HepG2 liver cells encapsulated in alginate hydrogels: a study of cell viability, morphology and drug metabolism.

Lan SF, Safiejko-Mroczka B, Starly B.

Toxicol In Vitro. 2010 Jun;24(4):1314-23. doi: 10.1016/j.tiv.2010.02.015. Epub 2010 Feb 18.

PMID:
20171269
11.

Resistance mechanisms to mitochondrial electron transport inhibitors in a field-collected strain of Tetranychus urticae Koch (Acari: Tetranychidae).

Van Pottelberge S, Van Leeuwen T, Nauen R, Tirry L.

Bull Entomol Res. 2009 Feb;99(1):23-31. doi: 10.1017/S0007485308006081. Epub 2008 Jul 1.

PMID:
18590597
12.

Inducibility of AhR-regulated CYP genes by beta-naphthoflavone in the liver, lung, kidney and heart of the pig.

Chirulli V, Marvasi L, Zaghini A, Fiorio R, Longo V, Gervasi PG.

Toxicology. 2007 Oct 30;240(1-2):25-37. Epub 2007 Jul 24.

PMID:
17804143
13.

Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide.

Sun L, Chen CS, Waxman DJ, Liu H, Halpert JR, Kumar S.

Arch Biochem Biophys. 2007 Feb 15;458(2):167-74. Epub 2007 Jan 8.

14.

Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide.

Kumar S, Sun L, Liu H, Muralidhara BK, Halpert JR.

Protein Eng Des Sel. 2006 Dec;19(12):547-54. Epub 2006 Oct 18.

PMID:
17050590
15.
16.

Biochemical analysis of a chlorfenapyr-selected resistant strain of Tetranychus urticae Koch.

Van Leeuwen T, Van Pottelberge S, Tirry L.

Pest Manag Sci. 2006 May;62(5):425-33.

PMID:
16550506
18.
19.
20.

Functional characterization of cytochrome P450 2B6 allelic variants.

Jinno H, Tanaka-Kagawa T, Ohno A, Makino Y, Matsushima E, Hanioka N, Ando M.

Drug Metab Dispos. 2003 Apr;31(4):398-403.

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