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Items: 1 to 20 of 324

  • Filters activated: Toxicology. Clear all to show 1458 items.
1.

Synthesis and biological evaluation of β2-adrenoceptor agonists bearing the 2-amino-2-phenylethanol scaffold.

Ge X, Woo AY, Xing G, Lu Y, Mo Y, Zhao Y, Lan Y, Li J, Yan H, Pan L, Zhang Y, Lin B, Cheng M.

Eur J Med Chem. 2018 May 25;152:424-435. doi: 10.1016/j.ejmech.2018.04.041. Epub 2018 Apr 30.

PMID:
29751236
2.

Structural basis for the catalytic mechanism and α-ketoglutarate cooperativity of glutamate dehydrogenase.

Prakash P, Punekar NS, Bhaumik P.

J Biol Chem. 2018 Apr 27;293(17):6241-6258. doi: 10.1074/jbc.RA117.000149. Epub 2018 Mar 14.

PMID:
29540480
3.

Activity of Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside, its Hydrochloride, and N,N-dialkyl Derivatives Against Non-albicans Candida Isolates.

Dawgul MA, Grzywacz D, Liberek B, Kamysz W, Myszka H.

Med Chem. 2018;14(5):460-467. doi: 10.2174/1573406414666180226164747.

PMID:
29485003
4.
5.

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism.

Dando I, Pacchiana R, Pozza ED, Cataldo I, Bruno S, Conti P, Cordani M, Grimaldi A, Butera G, Caraglia M, Scarpa A, Palmieri M, Donadelli M.

Free Radic Biol Med. 2017 Dec;113:176-189. doi: 10.1016/j.freeradbiomed.2017.09.022. Epub 2017 Sep 27.

PMID:
28962872
6.

Phototoxic assessment of a sunscreen formulation and its excipients: An in vivo and in vitro study.

Hossy BH, da Costa Leitão AA, Dos Santos EP, Matsuda M, Rezende LB, Rurr JSC, Pinto AV, Ramos-E-Silva M, de Pádula M, de Oliveira Miguel NC.

J Photochem Photobiol B. 2017 Aug;173:545-550. doi: 10.1016/j.jphotobiol.2017.06.043. Epub 2017 Jun 29.

PMID:
28692926
7.

Synthesis of a new deoxyglucose derivative modified near-infrared fluorescent probe for tumor diagnosis.

Sun C, Du W, Wang B, Yao Z, Liu J, Wang J, Xie W, Wu T, Fan Y, Yang H.

Biochem Biophys Res Commun. 2017 Jun 24;488(2):340-347. doi: 10.1016/j.bbrc.2017.05.046. Epub 2017 May 9.

PMID:
28499871
8.

Development of a mechanistic model for prediction of CO2 capture from gas mixtures by amine solutions in porous membranes.

Ghadiri M, Marjani A, Shirazian S.

Environ Sci Pollut Res Int. 2017 Jun;24(16):14508-14515. doi: 10.1007/s11356-017-9048-8. Epub 2017 Apr 27.

PMID:
28452027
9.

Relationship between [14C]MeAIB uptake and amino acid transporter family gene expression levels or proliferative activity in a pilot study in human carcinoma cells: Comparison with [3H]methionine uptake.

Kagawa S, Nishii R, Higashi T, Yamauchi H, Ogawa E, Okudaira H, Kobayashi M, Yoshimoto M, Shikano N, Kawai K.

Nucl Med Biol. 2017 Jun;49:8-15. doi: 10.1016/j.nucmedbio.2017.01.008. Epub 2017 Jan 26.

PMID:
28284101
10.

Inhibition of glutamate receptors reduces the homocysteine-induced whole blood platelet aggregation but does not affect superoxide anion generation or platelet membrane fluidization.

Karolczak K, Pieniazek A, Watala C.

Platelets. 2017 Jan;28(1):90-98. doi: 10.1080/09537104.2016.1204438. Epub 2016 Aug 25.

PMID:
27560773
11.

The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits.

Witkin JM, Monn JA, Schoepp DD, Li X, Overshiner C, Mitchell SN, Carter G, Johnson B, Rasmussen K, Rorick-Kehn LM.

J Pharmacol Exp Ther. 2016 Jul;358(1):71-82. doi: 10.1124/jpet.116.233627. Epub 2016 May 12.

12.

Potent anti-proliferative actions of a non-diuretic glucosamine derivative of ethacrynic acid.

Punganuru SR, Mostofa AGM, Madala HR, Basak D, Srivenugopal KS.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2829-2833. doi: 10.1016/j.bmcl.2016.04.062. Epub 2016 Apr 22.

PMID:
27156773
13.

Reduced mucosal side-effects of acetylsalicylic acid after conjugation with tris-hydroxymethyl-aminomethane. Synthesis and biological evaluation of a new anti-inflammatory compound.

Varga G, Lajkó N, Ugocsai M, Érces D, Horváth G, Tóth G, Boros M, Ghyczy M.

Eur J Pharmacol. 2016 Jun 15;781:181-9. doi: 10.1016/j.ejphar.2016.04.019. Epub 2016 Apr 12.

PMID:
27079640
14.

D-chiro-inositol glycan reduces food intake by regulating hypothalamic neuropeptide expression via AKT-FoxO1 pathway.

Jeon Y, Aja S, Ronnett GV, Kim EK.

Biochem Biophys Res Commun. 2016 Feb 19;470(4):818-23. doi: 10.1016/j.bbrc.2016.01.115. Epub 2016 Jan 21.

PMID:
26802467
15.

2-Amino-2-deoxy-glucose conjugated cobalt ferrite magnetic nanoparticle (2DG-MNP) as a targeting agent for breast cancer cells.

Aşık E, Aslan TN, Volkan M, Güray NT.

Environ Toxicol Pharmacol. 2016 Jan;41:272-8. doi: 10.1016/j.etap.2015.12.004. Epub 2015 Dec 17.

PMID:
26761626
16.

Synthesis and Biological Evaluation of (S)-Amino-2-methyl-4-[(76)Br]bromo-3-(E)-butenoic Acid (BrVAIB) for Brain Tumor Imaging.

Burkemper JL, Huang C, Li A, Yuan L, Rich K, McConathy J, Lapi SE.

J Med Chem. 2015 Nov 12;58(21):8542-52. doi: 10.1021/acs.jmedchem.5b01035. Epub 2015 Oct 20.

17.

Preclinical evaluation of 2-amino-2-[11C]methyl-butanoic acid as a potential tumor-imaging agent in a mouse model.

Suzuki C, Tsuji AB, Kato K, Sudo H, Zhang MR, Saga T.

Nucl Med Commun. 2015 Nov;36(11):1107-12. doi: 10.1097/MNM.0000000000000364.

PMID:
26259115
18.

Crystal Structure, Cytotoxicity and Interaction with DNA of Zinc (II) Complexes with o-Vanillin Schiff Base Ligands.

Niu MJ, Li Z, Chang GL, Kong XJ, Hong M, Zhang QF.

PLoS One. 2015 Jun 26;10(6):e0130922. doi: 10.1371/journal.pone.0130922. eCollection 2015.

19.

Molecular Determinants of N-Acetylglucosamine Recognition and Turnover by N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside Deacetylase (MshB).

Huang X, Hernick M.

Biochemistry. 2015 Jun 23;54(24):3784-90. doi: 10.1021/acs.biochem.5b00068. Epub 2015 Jun 9.

PMID:
26024468
20.

FTY720 Attenuates Acute Pancreatitis in Hypertriglyceridemic Apolipoprotein CIII Transgenic Mice.

Liu J, Xu P, Zhang L, Kayoumu A, Wang Y, Wang M, Gao M, Zhang X, Wang Y, Liu G.

Shock. 2015 Sep;44(3):280-6. doi: 10.1097/SHK.0000000000000400.

PMID:
25944794

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