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The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.

Knecht KM, Buzovetsky O, Schneider C, Thomas D, Srikanth V, Kaderali L, Tofoleanu F, Reiss K, Ferreirós N, Geisslinger G, Batista VS, Ji X, Cinatl J Jr, Keppler OT, Xiong Y.

Proc Natl Acad Sci U S A. 2018 Oct 10. pii: 201805593. doi: 10.1073/pnas.1805593115. [Epub ahead of print]


Efficacy of common salvage chemotherapy regimens in patients with refractory or relapsed acute myeloid leukemia: A retrospective cohort study.

Xu J, Lv TT, Zhou XF, Huang Y, Liu DD, Yuan GL.

Medicine (Baltimore). 2018 Sep;97(39):e12102. doi: 10.1097/MD.0000000000012102.


Fludarabine and busulfan plus low-dose TBI as reduced intensity conditioning in older patients undergoing allogeneic hematopoietic cell transplant for myeloid malignancies.

Khalil MMI, Messner HA, Lipton JH, Kim DD, Viswabandya A, Thyagu S, Deotare U, Michelis FV.

Ann Hematol. 2018 Oct;97(10):1975-1985. doi: 10.1007/s00277-018-3391-9. Epub 2018 Jun 11.


Point: Does Chemoimmunotherapy Still Have a Role in CLL? Chemoimmunotherapy With FCR Is Still an Important Option in CLL.

Thompson PA, Tam CS.

Oncology (Williston Park). 2018 Jun;32(6):291-2, 294-6. No abstract available.


Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study.

Egle A, Steurer M, Melchardt T, Weiss L, Gassner FJ, Zaborsky N, Geisberger R, Catakovic K, Hartmann TN, Pleyer L, Voskova D, Thaler J, Lang A, Girschikofsky M, Petzer A, Greil R.

Ann Hematol. 2018 Oct;97(10):1825-1839. doi: 10.1007/s00277-018-3380-z. Epub 2018 Jun 4. Erratum in: Ann Hematol. 2018 Jun 23;:.


An ultrasonic nanobubble-mediated PNP/fludarabine suicide gene system: A new approach for the treatment of hepatocellular carcinoma.

Zhang B, Chen M, Zhang Y, Chen W, Zhang L, Chen L.

PLoS One. 2018 May 2;13(5):e0196686. doi: 10.1371/journal.pone.0196686. eCollection 2018.


Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.

Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A.

J Med Case Rep. 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. Review.


FDG PET and MRI Findings in a Case of Bing-Neel Syndrome.

Bund C, Lhermitte B, De Seze J, Kremer S, Namer IJ.

Clin Nucl Med. 2018 Apr;43(4):262-264. doi: 10.1097/RLU.0000000000002019.


A phase I-II study of plerixafor in combination with fludarabine, idarubicin, cytarabine, and G-CSF (PLERIFLAG regimen) for the treatment of patients with the first early-relapsed or refractory acute myeloid leukemia.

Martínez-Cuadrón D, Boluda B, Martínez P, Bergua J, Rodríguez-Veiga R, Esteve J, Vives S, Serrano J, Vidriales B, Salamero O, Cordón L, Sempere A, Jiménez-Ubieto A, Prieto-Delgado J, Díaz-Beyá M, Garrido A, Benavente C, Pérez-Simón JA, Moscardó F, Sanz MA, Montesinos P; CETLAM and PETHEMA groups.

Ann Hematol. 2018 May;97(5):763-772. doi: 10.1007/s00277-018-3229-5. Epub 2018 Feb 2. Erratum in: Ann Hematol. 2018 Feb 23;:.


Coexistence of t(2;14;11)(p16.1;q32;q23) and t(14;19)(q32;q13.3) chromosome translocations in a patient with chronic lymphocytic leukemia: A case report.

Liu G, Wen Z, Lu X, Kim YM, Wang X, Crew RM, Cherry MA, Li S, Liu Y.

Medicine (Baltimore). 2017 Dec;96(51):e9169. doi: 10.1097/MD.0000000000009169.


Long-term efficacy and toxicity of rituximab plus fludarabine and mitoxantrone (R-FM) for gastric marginal zone lymphoma: a single-center experience and literature review.

Cencini E, Fabbri A, Lauria F, Bocchia M.

Ann Hematol. 2018 May;97(5):821-829. doi: 10.1007/s00277-018-3243-7. Epub 2018 Jan 16. Review.


[Outcomes of alternative donor allogeneic hematopoietic stem cell transplantation for Fanconi anemia: a five cases report].

Wang WJ, Sun YQ, Tang FF, Han TT, Mo XD, Wang JZ, Zhang XH, Huang XJ, Xu LP.

Zhonghua Nei Ke Za Zhi. 2018 Jan 1;57(1):54-56. doi: 10.3760/cma.j.issn.0578-1426.2018.01.010. Chinese.


The struggle to do no harm in clinical trials.

Schmidt C.

Nature. 2017 Dec 21;552(7685):S74-S75. doi: 10.1038/d41586-017-08705-4. No abstract available.


Outcomes of previously untreated elderly patients with AML: a propensity score-matched comparison of clofarabine vs. FLAG.

Scappaticci GB, Marini BL, Nachar VR, Uebel JR, Vulaj V, Crouch A, Bixby DL, Talpaz M, Perissinotti AJ.

Ann Hematol. 2018 Apr;97(4):573-584. doi: 10.1007/s00277-017-3217-1. Epub 2017 Dec 29.


A case report: Does the ulcer belong to esophageal carcinoma or HIV?

Jia N, Tang Y, Li Y, Gan Y.

Medicine (Baltimore). 2017 Dec;96(49):e9137. doi: 10.1097/MD.0000000000009137.


Analysis of factors affecting initial cyclosporine level and its impact on post transplant outcomes in acute leukemia.

Gupta A, Punatar S, Gawande J, Mathew L, Kannan S, Khattry N.

J Cancer Res Ther. 2017 Oct-Dec;13(6):981-988. doi: 10.4103/0973-1482.157338.


The mutational landscape of chronic lymphocytic leukemia and its impact on prognosis and treatment.

Gaidano G, Rossi D.

Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):329-337. doi: 10.1182/asheducation-2017.1.329. Review.


The absolute percent deviation of IGHV mutation rather than a 98% cut-off predicts survival of chronic lymphocytic leukaemia patients treated with fludarabine, cyclophosphamide and rituximab.

Gocke CD, Gladstone DE.

Br J Haematol. 2018 Jan;180(1):7-8. doi: 10.1111/bjh.15015. Epub 2017 Dec 3. No abstract available.


[Dose adaptation of the drugs used for hematopoietic stem-cell transplantation in patients with comorbidity: Obesity, chronic renal disease or hepatopathy: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

Simon N, Coiteux V, Bruno B, Taque S, Charbonnier A, Souchet L, Vincent L, Yakoub-Agha I, Chalandon Y.

Bull Cancer. 2017 Dec;104(12S):S99-S105. doi: 10.1016/j.bulcan.2017.07.010. Epub 2017 Nov 23. Review. French.


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