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Items: 16

  • Filters activated: Cancer. Clear all to show 72 items.
1.

Ordered chimerogenesis applied to CYP2B P450 enzymes.

Lautier T, Urban P, Loeper J, Jezequel L, Pompon D, Truan G.

Biochim Biophys Acta. 2016 Jul;1860(7):1395-403. doi: 10.1016/j.bbagen.2016.03.028. Epub 2016 Mar 23.

PMID:
27015760
2.

Induction of cytochrome P450 enzymes in primary equine hepatocyte culture.

Stefanski A, Mevissen M, Möller AM, Kuehni-Boghenbor K, Schmitz A.

Toxicol In Vitro. 2013 Oct;27(7):2023-30. doi: 10.1016/j.tiv.2013.07.009. Epub 2013 Aug 1.

PMID:
23916975
3.

Nanosilver particle effects on drug metabolism in vitro.

Lamb JG, Hathaway LB, Munger MA, Raucy JL, Franklin MR.

Drug Metab Dispos. 2010 Dec;38(12):2246-51. doi: 10.1124/dmd.110.035238. Epub 2010 Sep 22.

4.

Long-term cultivation of HepG2 liver cells encapsulated in alginate hydrogels: a study of cell viability, morphology and drug metabolism.

Lan SF, Safiejko-Mroczka B, Starly B.

Toxicol In Vitro. 2010 Jun;24(4):1314-23. doi: 10.1016/j.tiv.2010.02.015. Epub 2010 Feb 18.

PMID:
20171269
5.

Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide.

Sun L, Chen CS, Waxman DJ, Liu H, Halpert JR, Kumar S.

Arch Biochem Biophys. 2007 Feb 15;458(2):167-74. Epub 2007 Jan 8.

6.
8.

Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison.

Löfgren S, Hagbjörk AL, Ekman S, Fransson-Steen R, Terelius Y.

Xenobiotica. 2004 Sep;34(9):811-34.

PMID:
15742976
9.

EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme.

Ogura H, Nishida CR, Hoch UR, Perera R, Dawson JH, Ortiz de Montellano PR.

Biochemistry. 2004 Nov 23;43(46):14712-21.

PMID:
15544342
10.

Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity.

Huynh HT, Teel RW.

Anticancer Res. 2002 May-Jun;22(3):1699-703.

PMID:
12168856
11.

Effect of tamoxifen on the enzymatic activity of human cytochrome CYP2B6.

Sridar C, Kent UM, Notley LM, Gillam EM, Hollenberg PF.

J Pharmacol Exp Ther. 2002 Jun;301(3):945-52.

12.

Inhibition of cytochromes P450 by antifungal imidazole derivatives.

Zhang W, Ramamoorthy Y, Kilicarslan T, Nolte H, Tyndale RF, Sellers EM.

Drug Metab Dispos. 2002 Mar;30(3):314-8.

13.

Metabolism of N-nitrosobenzylmethylamine by human cytochrome P-450 enzymes.

Morse MA, Lu J, Stoner GD, Murphy SE, Peterson LA.

J Toxicol Environ Health A. 1999 Dec 10;58(7):397-411.

PMID:
10616189
14.

Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH- and hydroperoxide-supported activities.

Hanna IH, Teiber JF, Kokones KL, Hollenberg PF.

Arch Biochem Biophys. 1998 Feb 15;350(2):324-32.

PMID:
9473308
15.

Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.

Code EL, Crespi CL, Penman BW, Gonzalez FJ, Chang TK, Waxman DJ.

Drug Metab Dispos. 1997 Aug;25(8):985-93.

16.

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