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Demographic, Knowledge and Impact Analysis of 57,627 Antibiotic Guardians Who Have Pledged to Contribute to Tackling Antimicrobial Resistance.

Newitt S, Oloyede O, Puleston R, Hopkins S, Ashiru-Oredope D.

Antibiotics (Basel). 2019 Mar 9;8(1). pii: E21. doi: 10.3390/antibiotics8010021.


Duration of antibiotic treatment for common infections in English primary care: cross sectional analysis and comparison with guidelines.

Pouwels KB, Hopkins S, Llewelyn MJ, Walker AS, McNulty CA, Robotham JV.

BMJ. 2019 Feb 27;364:l440. doi: 10.1136/bmj.l440.


Oral versus Intravenous Antibiotics for Bone and Joint Infection.

Li HK, Rombach I, Zambellas R, Walker AS, McNally MA, Atkins BL, Lipsky BA, Hughes HC, Bose D, Kümin M, Scarborough C, Matthews PC, Brent AJ, Lomas J, Gundle R, Rogers M, Taylor A, Angus B, Byren I, Berendt AR, Warren S, Fitzgerald FE, Mack DJF, Hopkins S, Folb J, Reynolds HE, Moore E, Marshall J, Jenkins N, Moran CE, Woodhouse AF, Stafford S, Seaton RA, Vallance C, Hemsley CJ, Bisnauthsing K, Sandoe JAT, Aggarwal I, Ellis SC, Bunn DJ, Sutherland RK, Barlow G, Cooper C, Geue C, McMeekin N, Briggs AH, Sendi P, Khatamzas E, Wangrangsimakul T, Wong THN, Barrett LK, Alvand A, Old CF, Bostock J, Paul J, Cooke G, Thwaites GE, Bejon P, Scarborough M; OVIVA Trial Collaborators.

N Engl J Med. 2019 Jan 31;380(5):425-436. doi: 10.1056/NEJMoa1710926.


Antimicrobial stewardship: an evaluation of structure and process and their association with antimicrobial prescribing in NHS hospitals in England.

Scobie A, Budd EL, Harris RJ, Hopkins S, Shetty N.

J Antimicrob Chemother. 2019 Apr 1;74(4):1143-1152. doi: 10.1093/jac/dky538.


Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update.

Vonk Noordegraaf A, Chin KM, Haddad F, Hassoun PM, Hemnes AR, Hopkins SR, Kawut SM, Langleben D, Lumens J, Naeije R.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801900. doi: 10.1183/13993003.01900-2018. Print 2019 Jan.


Blended Facilitation as an Effective Implementation Strategy for Quality Improvement and Research in Nursing Homes.

Pimentel CB, Mills WL, Palmer JA, Dillon K, Sullivan JL, Wewiorski NJ, Snow AL, Allen RS, Hopkins SD, Hartmann CW.

J Nurs Care Qual. 2018 Nov 21. doi: 10.1097/NCQ.0000000000000376. [Epub ahead of print]


Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017.

Plachouras D, Kärki T, Hansen S, Hopkins S, Lyytikäinen O, Moro ML, Reilly J, Zarb P, Zingg W, Kinross P, Weist K, Monnet DL, Suetens C; The Point Prevalence Survey Study Group.

Euro Surveill. 2018 Nov;23(46). doi: 10.2807/1560-7917.ES.23.46.1800393.


Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017.

Suetens C, Latour K, Kärki T, Ricchizzi E, Kinross P, Moro ML, Jans B, Hopkins S, Hansen S, Lyytikäinen O, Reilly J, Deptula A, Zingg W, Plachouras D, Monnet DL; The Healthcare-Associated Infections Prevalence Study Group.

Euro Surveill. 2018 Nov;23(46). doi: 10.2807/1560-7917.ES.2018.23.46.1800516.


Antimicrobial Stewardship Programmes in Community Healthcare Organisations in England: A Cross-Sectional Survey to Assess Implementation of Programmes and National Toolkits.

Ashiru-Oredope D, Doble A, Akpan MR, Hansraj S, Shebl NA, Ahmad R, Hopkins S.

Antibiotics (Basel). 2018 Nov 7;7(4). pii: E97. doi: 10.3390/antibiotics7040097.


Using linked electronic health records to report healthcare-associated infections.

Quan TP, Hope R, Clarke T, Moroney R, Butcher L, Knight P, Crook D, Hopkins S, Peto TEA, Johnson AP, Walker AS.

PLoS One. 2018 Nov 7;13(11):e0206860. doi: 10.1371/journal.pone.0206860. eCollection 2018.


Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT.

Thwaites GE, Scarborough M, Szubert A, Saramago Goncalves P, Soares M, Bostock J, Nsutebu E, Tilley R, Cunningham R, Greig J, Wyllie SA, Wilson P, Auckland C, Cairns J, Ward D, Lal P, Guleri A, Jenkins N, Sutton J, Wiselka M, Armando GR, Graham C, Chadwick PR, Barlow G, Gordon NC, Young B, Meisner S, McWhinney P, Price DA, Harvey D, Nayar D, Jeyaratnam D, Planche T, Minton J, Hudson F, Hopkins S, Williams J, Török ME, Llewelyn MJ, Edgeworth JD, Walker AS.

Health Technol Assess. 2018 Oct;22(59):1-148. doi: 10.3310/hta22590.


Exploring the relationship between primary care antibiotic prescribing for urinary tract infections, Escherichia coli bacteraemia incidence and antimicrobial resistance: an ecological study.

Lishman H, Costelloe C, Hopkins S, Johnson AP, Hope R, Guy R, Muller-Pebody B, Holmes A, Aylin P.

Int J Antimicrob Agents. 2018 Dec;52(6):790-798. doi: 10.1016/j.ijantimicag.2018.08.013. Epub 2018 Aug 24.


Quantifying where human acquisition of antibiotic resistance occurs: a mathematical modelling study.

Knight GM, Costelloe C, Deeny SR, Moore LSP, Hopkins S, Johnson AP, Robotham JV, Holmes AH.

BMC Med. 2018 Aug 23;16(1):137. doi: 10.1186/s12916-018-1121-8.


Trends over time in Escherichia coli bloodstream infections, urinary tract infections, and antibiotic susceptibilities in Oxfordshire, UK, 1998-2016: a study of electronic health records.

Vihta KD, Stoesser N, Llewelyn MJ, Quan TP, Davies T, Fawcett NJ, Dunn L, Jeffery K, Butler CC, Hayward G, Andersson M, Morgan M, Oakley S, Mason A, Hopkins S, Wyllie DH, Crook DW, Wilcox MH, Johnson AP, Peto TEA, Walker AS.

Lancet Infect Dis. 2018 Oct;18(10):1138-1149. doi: 10.1016/S1473-3099(18)30353-0. Epub 2018 Aug 17.


Late Presentation of Infected Silicone Granulomas in the Lower Limb.

Jessop ZM, Welck M, Zinser E, Garlick N, Hopkins S.

Clin Med Insights Arthritis Musculoskelet Disord. 2018 Feb 22;11:1179544118759020. doi: 10.1177/1179544118759020. eCollection 2018.


Potential for reducing inappropriate antibiotic prescribing in English primary care.

Smieszek T, Pouwels KB, Dolk FCK, Smith DRM, Hopkins S, Sharland M, Hay AD, Moore MV, Robotham JV.

J Antimicrob Chemother. 2018 Feb 1;73(suppl_2):ii36-ii43. doi: 10.1093/jac/dkx500.


Effect of general practice characteristics and antibiotic prescribing on Escherichia coli antibiotic non-susceptibility in the West Midlands region of England: a 4 year ecological study.

Ironmonger D, Edeghere O, Verlander NQ, Gossain S, Hopkins S, Hilton B, Hawkey PM.

J Antimicrob Chemother. 2018 Mar 1;73(3):787-794. doi: 10.1093/jac/dkx465.


Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.

Thwaites GE, Scarborough M, Szubert A, Nsutebu E, Tilley R, Greig J, Wyllie SA, Wilson P, Auckland C, Cairns J, Ward D, Lal P, Guleri A, Jenkins N, Sutton J, Wiselka M, Armando GR, Graham C, Chadwick PR, Barlow G, Gordon NC, Young B, Meisner S, McWhinney P, Price DA, Harvey D, Nayar D, Jeyaratnam D, Planche T, Minton J, Hudson F, Hopkins S, Williams J, Török ME, Llewelyn MJ, Edgeworth JD, Walker AS; United Kingdom Clinical Infection Research Group (UKCIRG).

Lancet. 2018 Feb 17;391(10121):668-678. doi: 10.1016/S0140-6736(17)32456-X. Epub 2017 Dec 14.


Frequency and significance of indeterminate and borderline Quantiferon Gold TB IGRA results.

Brown J, Kumar K, Reading J, Harvey J, Murthy S, Capocci S, Hopkins S, Seneviratne S, Cropley I, Lipman M.

Eur Respir J. 2017 Oct 26;50(4). pii: 1701267. doi: 10.1183/13993003.01267-2017. Print 2017 Oct. No abstract available.


An investigation of antifungal stewardship programmes in England.

Micallef C, Ashiru-Oredope D, Hansraj S, Denning DW, Agrawal SG, Manuel RJ, Schelenz S, Guy R, Muller-Pebody B, Patel R, Howard P, Hopkins S, Johnson E, Enoch DA.

J Med Microbiol. 2017 Nov;66(11):1581-1589. doi: 10.1099/jmm.0.000612. Epub 2017 Oct 25.


Trends and patterns in antibiotic prescribing among out-of-hours primary care providers in England, 2010-14.

Edelstein M, Agbebiyi A, Ashiru-Oredope D, Hopkins S.

J Antimicrob Chemother. 2017 Dec 1;72(12):3490-3495. doi: 10.1093/jac/dkx323.


The ethics of setting national antibiotic policies using financial incentives.

Li G, Hooper C, Papanikitas A, Hopkins S, Sharland M.

Br J Gen Pract. 2017 Sep;67(662):419-420. doi: 10.3399/bjgp17X692465. No abstract available.


The antibiotic course has had its day.

Llewelyn MJ, Fitzpatrick JM, Darwin E, SarahTonkin-Crine, Gorton C, Paul J, Peto TEA, Yardley L, Hopkins S, Walker AS.

BMJ. 2017 Jul 26;358:j3418. doi: 10.1136/bmj.j3418. No abstract available.


Impact of recurrent Clostridium difficile infection: hospitalization and patient quality of life.

Wilcox MH, Ahir H, Coia JE, Dodgson A, Hopkins S, Llewelyn MJ, Settle C, Mclain-Smith S, Marcella SW.

J Antimicrob Chemother. 2017 Sep 1;72(9):2647-2656. doi: 10.1093/jac/dkx174.


An association between pulmonary Mycobacterium avium-intracellulare complex infections and biomarkers of Th2-type inflammation.

Pfeffer PE, Hopkins S, Cropley I, Lowe DM, Lipman M.

Respir Res. 2017 May 15;18(1):93. doi: 10.1186/s12931-017-0579-9.


Secondary use of data from hospital electronic prescribing and pharmacy systems to support the quality and safety of antimicrobial use: a systematic review.

Micallef C, Chaudhry NT, Holmes AH, Hopkins S, Benn J, Franklin BD.

J Antimicrob Chemother. 2017 Jul 1;72(7):1880-1885. doi: 10.1093/jac/dkx082. Review.


Ventilation heterogeneity measured by multiple breath inert gas testing is not affected by inspired oxygen concentration in healthy humans.

Hopkins SR, Elliott AR, Prisk GK, Darquenne C.

J Appl Physiol (1985). 2017 Jun 1;122(6):1379-1387. doi: 10.1152/japplphysiol.01013.2016. Epub 2017 Mar 9.


Measurement of the distribution of ventilation-perfusion ratios in the human lung with proton MRI: comparison with the multiple inert-gas elimination technique.

Sá RC, Henderson AC, Simonson T, Arai TJ, Wagner H, Theilmann RJ, Wagner PD, Prisk GK, Hopkins SR.

J Appl Physiol (1985). 2017 Jul 1;123(1):136-146. doi: 10.1152/japplphysiol.00804.2016. Epub 2017 Mar 9.


A Risk Assessment of Antibiotic Pan-Drug-Resistance in the UK: Bayesian Analysis of an Expert Elicitation Study.

Carter D, Charlett A, Conti S, Robotham JV, Johnson AP, Livermore DM, Fowler T, Sharland M, Hopkins S, Woodford N, Burgess P, Dobra S.

Antibiotics (Basel). 2017 Mar 7;6(1). pii: E9. doi: 10.3390/antibiotics6010009.


Antimicrobial stewardship: we know it works; time to make sure it is in place everywhere.

Plachouras D, Hopkins S.

Cochrane Database Syst Rev. 2017 Feb 9;2:ED000119. doi: 10.1002/14651858.ED000119. No abstract available.


Effects of control interventions on Clostridium difficile infection in England: an observational study.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Golubchik T, Harding RM, Wilson DJ, Griffiths D, Vaughan A, Finney JM, Wyllie DH, Oakley SJ, Fawley WN, Freeman J, Morris K, Martin J, Howard P, Gorbach S, Goldstein EJC, Citron DM, Hopkins S, Hope R, Johnson AP, Wilcox MH, Peto TEA, Walker AS, Crook DW; Modernising Medical Microbiology Informatics Group.

Lancet Infect Dis. 2017 Apr;17(4):411-421. doi: 10.1016/S1473-3099(16)30514-X. Epub 2017 Jan 25.


Health-care-associated infections in neonates, children, and adolescents: an analysis of paediatric data from the European Centre for Disease Prevention and Control point-prevalence survey.

Zingg W, Hopkins S, Gayet-Ageron A, Holmes A, Sharland M, Suetens C; ECDC PPS study group.

Lancet Infect Dis. 2017 Apr;17(4):381-389. doi: 10.1016/S1473-3099(16)30517-5. Epub 2017 Jan 13.


Impact of long-term care facility residence on the antibiotic resistance of urinary tract Escherichia coli and Klebsiella.

Rosello A, Hayward AC, Hopkins S, Horner C, Ironmonger D, Hawkey PM, Deeny SR.

J Antimicrob Chemother. 2017 Apr 1;72(4):1184-1192. doi: 10.1093/jac/dkw555.


Susceptibility to high-altitude pulmonary edema is associated with a more uniform distribution of regional specific ventilation.

Patz MD, Sá RC, Darquenne C, Elliott AR, Asadi AK, Theilmann RJ, Dubowitz DJ, Swenson ER, Prisk GK, Hopkins SR.

J Appl Physiol (1985). 2017 Apr 1;122(4):844-852. doi: 10.1152/japplphysiol.00494.2016. Epub 2017 Jan 5.


Electronic prescribing system design priorities for antimicrobial stewardship: a cross-sectional survey of 142 UK infection specialists.

Hand KS, Cumming D, Hopkins S, Ewings S, Fox A, Theminimulle S, Porter RJ, Parker N, Munns J, Sheikh A, Keyser T, Puleston R.

J Antimicrob Chemother. 2017 Apr 1;72(4):1206-1216. doi: 10.1093/jac/dkw524.


Improving feedback of surveillance data on antimicrobial consumption, resistance and stewardship in England: putting the data at your Fingertips.

Johnson AP, Muller-Pebody B, Budd E, Ashiru-Oredope D, Ladenheim D, Hain D, Hope R, Bhattacharya A, Elgohari S, Guy R, Henderson K, Puleston R, Rooney G, Thelwall S, Wellington E, Lamagni T, Hopkins S.

J Antimicrob Chemother. 2017 Apr 1;72(4):953-956. doi: 10.1093/jac/dkw536.


Understanding the Impact of Interventions to Prevent Antimicrobial Resistant Infections in the Long-Term Care Facility: A Review and Practical Guide to Mathematical Modeling.

Rosello A, Horner C, Hopkins S, Hayward AC, Deeny SR.

Infect Control Hosp Epidemiol. 2017 Feb;38(2):216-225. doi: 10.1017/ice.2016.286. Epub 2016 Dec 19. Review.


Occupational Tuberculosis despite Minimal Nosocomial Contact in a Health Care Worker Undergoing Treatment with a Tumor Necrosis Factor Inhibitor.

Murphy ME, Wilmore S, Satta G, Witney A, Atzeni A, Sturgeon K, Cropley I, McHugh TD, Hopkins S, Lipman M.

Ann Am Thorac Soc. 2016 Dec;13(12):2275-2277. No abstract available.


The effect of lung deformation on the spatial distribution of pulmonary blood flow.

Arai TJ, Theilmann RJ, Sá RC, Villongco MT, Hopkins SR.

J Physiol. 2016 Nov 1;594(21):6333-6347. doi: 10.1113/JP272030. Epub 2016 Jul 8.


Case Studies in Physiology: The Case of the Giant Giraffe.

Hopkins SR, Wagner PD.

J Appl Physiol (1985). 2016 Dec;121(6):1379-1380. doi: 10.1152/japplphysiol.00891.2016. Epub 2016 Oct 14.


Physiology for the pulmonary functional imager.

Levin DL, Schiebler ML, Hopkins SR.

Eur J Radiol. 2017 Jan;86:308-312. doi: 10.1016/j.ejrad.2016.09.027. Epub 2016 Sep 28. Review.


A process evaluation of the UK-wide Antibiotic Guardian campaign: developing engagement on antimicrobial resistance.

Bhattacharya A, Hopkins S, Sallis A, Budd EL, Ashiru-Oredope D.

J Public Health (Oxf). 2017 Jun 1;39(2):e40-e47. doi: 10.1093/pubmed/fdw059.


Late Ebola virus relapse causing meningoencephalitis: a case report.

Jacobs M, Rodger A, Bell DJ, Bhagani S, Cropley I, Filipe A, Gifford RJ, Hopkins S, Hughes J, Jabeen F, Johannessen I, Karageorgopoulos D, Lackenby A, Lester R, Liu RS, MacConnachie A, Mahungu T, Martin D, Marshall N, Mepham S, Orton R, Palmarini M, Patel M, Perry C, Peters SE, Porter D, Ritchie D, Ritchie ND, Seaton RA, Sreenu VB, Templeton K, Warren S, Wilkie GS, Zambon M, Gopal R, Thomson EC.

Lancet. 2016 Jul 30;388(10043):498-503. doi: 10.1016/S0140-6736(16)30386-5. Epub 2016 May 18.


A cross-sectional survey of the acceptability of data collection processes for validation of a European point prevalence survey of healthcare-associated infections and antimicrobial use.

Price L, Reilly J, Godwin J, Cairns S, Hopkins S, Cookson B, Malcolm W, Hughes G, Lyytikäinen O, Coignard B, Hansen S.

J Infect Prev. 2016 May;17(3):122-126. doi: 10.1177/1757177416637131. Epub 2016 Mar 8.


Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans.

Basaran KE, Villongco M, Ho B, Ellis E, Zarndt R, Antonova J, Hopkins SR, Powell FL.

PLoS One. 2016 Jan 4;11(1):e0146087. doi: 10.1371/journal.pone.0146087. eCollection 2016.


Cost-effectiveness of national mandatory screening of all admissions to English National Health Service hospitals for meticillin-resistant Staphylococcus aureus: a mathematical modelling study.

Robotham JV, Deeny SR, Fuller C, Hopkins S, Cookson B, Stone S.

Lancet Infect Dis. 2016 Mar;16(3):348-56. doi: 10.1016/S1473-3099(15)00417-X. Epub 2015 Nov 28.


Thromboelastography in the Management of Coagulopathy Associated With Ebola Virus Disease.

Wilson AJ, Martin DS, Maddox V, Rattenbury S, Bland D, Bhagani S, Cropley I, Hopkins S, Mepham S, Rodger A, Warren S, Chowdary P, Jacobs M.

Clin Infect Dis. 2016 Mar 1;62(5):610-612. doi: 10.1093/cid/civ977. Epub 2015 Nov 26.


Terminal decontamination of the Royal Free London's high-level isolation unit after a case of Ebola virus disease using hydrogen peroxide vapor.

Otter JA, Mepham S, Athan B, Mack D, Smith R, Jacobs M, Hopkins S.

Am J Infect Control. 2016 Feb;44(2):233-5. doi: 10.1016/j.ajic.2015.08.025.


Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers.

Jacobs M, Aarons E, Bhagani S, Buchanan R, Cropley I, Hopkins S, Lester R, Martin D, Marshall N, Mepham S, Warren S, Rodger A.

Lancet Infect Dis. 2015 Nov;15(11):1300-4. doi: 10.1016/S1473-3099(15)00228-5. Epub 2015 Aug 25.


A statistical clustering approach to discriminating perfusion from conduit vessel signal contributions in a pulmonary ASL MR image.

Walker SC, Asadi AK, Hopkins SR, Buxton RB, Prisk GK.

NMR Biomed. 2015 Sep;28(9):1117-24. doi: 10.1002/nbm.3358. Epub 2015 Jul 16.

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