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Items: 1 to 50 of 339

1.

Running wheel access fails to resolve impaired sustainable health in mice feeding a high fat sucrose diet.

Reijne AC, Talarovicova A, Ciapaite J, Bruggink JE, Bleeker A, Groen AK, Reijngoud DJ, Bakker BM, van Dijk G.

Aging (Albany NY). 2019 Mar 11;11(5):1564-1579. doi: 10.18632/aging.101857.

2.

Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?"

Plat J, Baumgartner S, Vanmierlo T, Lütjohann D, Calkins KL, Burrin DG, Guthrie G, Thijs C, Te Velde AA, Vreugdenhil ACE, Sverdlov R, Garssen J, Wouters K, Trautwein EA, Wolfs TG, van Gorp C, Mulder MT, Riksen NP, Groen AK, Mensink RP.

Prog Lipid Res. 2019 Feb 26;74:87-102. doi: 10.1016/j.plipres.2019.02.003. [Epub ahead of print] Review.

3.

Weight Gain after Fecal Microbiota Transplantation in a Patient with Recurrent Underweight following Clinical Recovery from Anorexia Nervosa.

de Clercq NC, Frissen MN, Davids M, Groen AK, Nieuwdorp M.

Psychother Psychosom. 2019;88(1):58-60. doi: 10.1159/000495044. Epub 2019 Jan 9. No abstract available.

4.

Predictive value of targeted proteomics for coronary plaque morphology in patients with suspected coronary artery disease.

Bom MJ, Levin E, Driessen RS, Danad I, Van Kuijk CC, van Rossum AC, Narula J, Min JK, Leipsic JA, Belo Pereira JP, Taylor CA, Nieuwdorp M, Raijmakers PG, Koenig W, Groen AK, Stroes ESG, Knaapen P.

EBioMedicine. 2019 Jan;39:109-117. doi: 10.1016/j.ebiom.2018.12.033. Epub 2018 Dec 23.

5.

Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease.

Rau M, Rehman A, Dittrich M, Groen AK, Hermanns HM, Seyfried F, Beyersdorf N, Dandekar T, Rosenstiel P, Geier A.

United European Gastroenterol J. 2018 Dec;6(10):1496-1507. doi: 10.1177/2050640618804444. Epub 2018 Sep 30.

6.

AAV8-mediated gene transfer of microRNA-132 improves beta-cell function in mice fed a high fat diet.

Mulder NL, Havinga R, Kluiver JL, Groen AK, Kruit JK.

J Endocrinol. 2018 Oct 1. pii: JOE-18-0287.R2. doi: 10.1530/JOE-18-0287. [Epub ahead of print]

PMID:
30400037
7.

Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females.

Zhang X, Rimbert A, Balder W, Zwinderman AH, Kuivenhoven JA, Dallinga-Thie GM, Groen AK.

J Lipid Res. 2018 Nov;59(11):2174-2180. doi: 10.1194/jlr.M088930. Epub 2018 Sep 28.

8.

Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography.

Deschasaux M, Bouter KE, Prodan A, Levin E, Groen AK, Herrema H, Tremaroli V, Bakker GJ, Attaye I, Pinto-Sietsma SJ, van Raalte DH, Snijder MB, Nicolaou M, Peters R, Zwinderman AH, Bäckhed F, Nieuwdorp M.

Nat Med. 2018 Oct;24(10):1526-1531. doi: 10.1038/s41591-018-0160-1. Epub 2018 Aug 27.

PMID:
30150717
9.

Domain intelligible models.

Imangaliyev S, Prodan A, Nieuwdorp M, Groen AK, van Riel NAW, Levin E.

Methods. 2018 Oct 1;149:69-73. doi: 10.1016/j.ymeth.2018.06.011. Epub 2018 Jul 5.

PMID:
29981382
10.

Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy.

van Stee MF, de Graaf AA, Groen AK.

Cardiovasc Diabetol. 2018 Jun 30;17(1):94. doi: 10.1186/s12933-018-0738-4. Review.

11.

In Silico Analysis Identifies Intestinal Transit as a Key Determinant of Systemic Bile Acid Metabolism.

Sips FLP, Eggink HM, Hilbers PAJ, Soeters MR, Groen AK, van Riel NAW.

Front Physiol. 2018 Jun 8;9:631. doi: 10.3389/fphys.2018.00631. eCollection 2018.

12.

In vivo and in silico dynamics of the development of Metabolic Syndrome.

Rozendaal YJW, Wang Y, Paalvast Y, Tambyrajah LL, Li Z, Willems van Dijk K, Rensen PCN, Kuivenhoven JA, Groen AK, Hilbers PAJ, van Riel NAW.

PLoS Comput Biol. 2018 Jun 7;14(6):e1006145. doi: 10.1371/journal.pcbi.1006145. eCollection 2018 Jun.

13.

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects.

Bouter K, Bakker GJ, Levin E, Hartstra AV, Kootte RS, Udayappan SD, Katiraei S, Bahler L, Gilijamse PW, Tremaroli V, Stahlman M, Holleman F, van Riel NAW, Verberne HJ, Romijn JA, Dallinga-Thie GM, Serlie MJ, Ackermans MT, Kemper EM, Willems van Dijk K, Backhed F, Groen AK, Nieuwdorp M.

Clin Transl Gastroenterol. 2018 May 25;9(5):155. doi: 10.1038/s41424-018-0025-4.

14.

Gut microbiota, metabolism and psychopathology: A critical review and novel perspectives.

Groen RN, de Clercq NC, Nieuwdorp M, Hoenders HJR, Groen AK.

Crit Rev Clin Lab Sci. 2018 Jun;55(4):283-293. doi: 10.1080/10408363.2018.1463507. Epub 2018 Apr 20. Review.

PMID:
29673295
15.

Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites.

van Baar ACG, Prodan A, Wahlgren CD, Poulsen SS, Knop FK, Groen AK, Bergman JJ, Nieuwdorp M, Levin E.

Endocr Connect. 2018 May;7(5):673-680. doi: 10.1530/EC-18-0094. Epub 2018 Apr 18.

16.

Effect of Vegan Fecal Microbiota Transplantation on Carnitine- and Choline-Derived Trimethylamine-N-Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome.

Smits LP, Kootte RS, Levin E, Prodan A, Fuentes S, Zoetendal EG, Wang Z, Levison BS, Cleophas MCP, Kemper EM, Dallinga-Thie GM, Groen AK, Joosten LAB, Netea MG, Stroes ESG, de Vos WM, Hazen SL, Nieuwdorp M.

J Am Heart Assoc. 2018 Mar 26;7(7). pii: e008342. doi: 10.1161/JAHA.117.008342.

17.

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.

Zhang X, Mardinoglu A, Joosten LAB, Kuivenhoven JA, Li Y, Netea MG, Groen AK.

Front Physiol. 2018 Feb 27;9:139. doi: 10.3389/fphys.2018.00139. eCollection 2018.

18.

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.

van der Tuin SJL, Li Z, Berbée JFP, Verkouter I, Ringnalda LE, Neele AE, van Klinken JB, Rensen SS, Fu J, de Winther MPJ, Groen AK, Rensen PCN, Willems van Dijk K, Wang Y.

J Am Heart Assoc. 2018 Mar 10;7(6). pii: e008105. doi: 10.1161/JAHA.117.008105.

19.

Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice.

Chevre R, Trigueros-Motos L, Castaño D, Chua T, Corlianò M, Patankar JV, Sng L, Sim L, Juin TL, Carissimo G, Ng LFP, Yi CNJ, Eliathamby CC, Groen AK, Hayden MR, Singaraja RR.

FASEB J. 2018 Jul;32(7):3792-3802. doi: 10.1096/fj.201701084RR. Epub 2018 Feb 26.

PMID:
29481310
20.

The Duodenum harbors a Broad Untapped Therapeutic Potential.

van Baar ACG, Nieuwdorp M, Holleman F, Soeters MR, Groen AK, Bergman JJGHM.

Gastroenterology. 2018 Mar;154(4):773-777. doi: 10.1053/j.gastro.2018.02.010. Epub 2018 Feb 8. No abstract available.

PMID:
29428335
21.

Cholesterol Transport Revisited: A New Turbo Mechanism to Drive Cholesterol Excretion.

de Boer JF, Kuipers F, Groen AK.

Trends Endocrinol Metab. 2018 Feb;29(2):123-133. doi: 10.1016/j.tem.2017.11.006. Epub 2017 Dec 21. Review.

PMID:
29276134
22.

Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice.

Eggink HM, Tambyrajah LL, van den Berg R, Mol IM, van den Heuvel JK, Koehorst M, Groen AK, Boelen A, Kalsbeek A, Romijn JA, Rensen PCN, Kooijman S, Soeters MR.

J Endocrinol. 2018 Feb;236(2):85-97. doi: 10.1530/JOE-17-0503. Epub 2017 Dec 12.

PMID:
29233934
23.

Transintestinal cholesterol excretion in humans.

Reeskamp LF, Meessen ECE, Groen AK.

Curr Opin Lipidol. 2018 Feb;29(1):10-17. doi: 10.1097/MOL.0000000000000473.

PMID:
29189433
24.

Intestinal Ralstonia pickettii augments glucose intolerance in obesity.

Udayappan SD, Kovatcheva-Datchary P, Bakker GJ, Havik SR, Herrema H, Cani PD, Bouter KE, Belzer C, Witjes JJ, Vrieze A, de Sonnaville ESV, Chaplin A, van Raalte DH, Aalvink S, Dallinga-Thie GM, Heilig HGHJ, Bergström G, van der Meij S, van Wagensveld BA, Hoekstra JBL, Holleman F, Stroes ESG, Groen AK, Bäckhed F, de Vos WM, Nieuwdorp M.

PLoS One. 2017 Nov 22;12(11):e0181693. doi: 10.1371/journal.pone.0181693. eCollection 2017. Erratum in: PLoS One. 2018 Jan 30;13(1):e0192339.

25.

Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis.

Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, van den Berg SM, Pieterman EH, Princen HMG, Groen AK, Rensen PCN, Berbée JFP, Boon MR.

Atherosclerosis. 2017 Dec;267:116-126. doi: 10.1016/j.atherosclerosis.2017.10.030. Epub 2017 Oct 26.

PMID:
29121499
26.

Running-wheel activity delays mitochondrial respiratory flux decline in aging mouse muscle via a post-transcriptional mechanism.

Stolle S, Ciapaite J, Reijne AC, Talarovicova A, Wolters JC, Aguirre-Gamboa R, van der Vlies P, de Lange K, Neerincx PB, van der Vries G, Deelen P, Swertz MA, Li Y, Bischoff R, Permentier HP, Horvatovitch PL, Groen AK, van Dijk G, Reijngoud DJ, Bakker BM.

Aging Cell. 2018 Feb;17(1). doi: 10.1111/acel.12700. Epub 2017 Nov 9.

27.

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit.

Li Z, Yi CX, Katiraei S, Kooijman S, Zhou E, Chung CK, Gao Y, van den Heuvel JK, Meijer OC, Berbée JFP, Heijink M, Giera M, Willems van Dijk K, Groen AK, Rensen PCN, Wang Y.

Gut. 2018 Jul;67(7):1269-1279. doi: 10.1136/gutjnl-2017-314050. Epub 2017 Nov 3.

PMID:
29101261
28.

Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men.

Paalvast Y, Gerding A, Wang Y, Bloks VW, van Dijk TH, Havinga R, Willems van Dijk K, Rensen PCN, Bakker BM, Kuivenhoven JA, Groen AK.

Physiol Rep. 2017 Oct;5(19). pii: e13376. doi: 10.14814/phy2.13376. Epub 2017 Oct 16. Erratum in: Physiol Rep. 2018 Mar;6(6):e13608.

29.

Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats.

Eggink HM, Oosterman JE, de Goede P, de Vries EM, Foppen E, Koehorst M, Groen AK, Boelen A, Romijn JA, la Fleur SE, Soeters MR, Kalsbeek A.

Chronobiol Int. 2017;34(10):1339-1353. doi: 10.1080/07420528.2017.1363226. Epub 2017 Oct 13.

PMID:
29028359
30.

Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition.

Kootte RS, Levin E, Salojärvi J, Smits LP, Hartstra AV, Udayappan SD, Hermes G, Bouter KE, Koopen AM, Holst JJ, Knop FK, Blaak EE, Zhao J, Smidt H, Harms AC, Hankemeijer T, Bergman JJGHM, Romijn HA, Schaap FG, Olde Damink SWM, Ackermans MT, Dallinga-Thie GM, Zoetendal E, de Vos WM, Serlie MJ, Stroes ESG, Groen AK, Nieuwdorp M.

Cell Metab. 2017 Oct 3;26(4):611-619.e6. doi: 10.1016/j.cmet.2017.09.008.

31.

Nile Red Quantifier: a novel and quantitative tool to study lipid accumulation in patient-derived circulating monocytes using confocal microscopy.

Schnitzler JG, Bernelot Moens SJ, Tiessens F, Bakker GJ, Dallinga-Thie GM, Groen AK, Nieuwdorp M, Stroes ESG, Kroon J.

J Lipid Res. 2017 Nov;58(11):2210-2219. doi: 10.1194/jlr.D073197. Epub 2017 Sep 28.

32.

ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota.

Janssen AWF, Dijk W, Boekhorst J, Kuipers F, Groen AK, Lukovac S, Hooiveld GJEJ, Kersten S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt A):1056-1067. doi: 10.1016/j.bbalip.2017.07.005. Epub 2017 Jul 18.

PMID:
28733267
33.

Hepatocytes contribute to residual glucose production in a mouse model for glycogen storage disease type Ia.

Hijmans BS, Boss A, van Dijk TH, Soty M, Wolters H, Mutel E, Groen AK, Derks TGJ, Mithieux G, Heerschap A, Reijngoud DJ, Rajas F, Oosterveer MH.

Hepatology. 2017 Dec;66(6):2042-2054. doi: 10.1002/hep.29389. Epub 2017 Oct 30.

PMID:
28727166
34.

Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice.

Udayappan S, Manneras-Holm L, Chaplin-Scott A, Belzer C, Herrema H, Dallinga-Thie GM, Duncan SH, Stroes ESG, Groen AK, Flint HJ, Backhed F, de Vos WM, Nieuwdorp M.

NPJ Biofilms Microbiomes. 2016 Jul 6;2:16009. doi: 10.1038/npjbiofilms.2016.9. eCollection 2016.

35.

An unexpected role for bile acid synthesis in adaptation to low temperature.

Kuipers F, Groen AK.

Nat Med. 2017 Jul 11;23(7):800-802. doi: 10.1038/nm.4365. No abstract available.

PMID:
28697185
36.

Transhepatic bile acid kinetics in pigs and humans.

Eggink HM, van Nierop FS, Schooneman MG, Boelen A, Kalsbeek A, Koehorst M, Ten Have GAM, de Brauw LM, Groen AK, Romijn JA, Deutz NEP, Soeters MR.

Clin Nutr. 2018 Aug;37(4):1406-1414. doi: 10.1016/j.clnu.2017.06.015. Epub 2017 Jun 19.

PMID:
28669667
37.

The effects of amoxicillin and vancomycin on parameters reflecting cholesterol metabolism.

Baumgartner S, Reijnders D, Konings MCJM, Groen AK, Lütjohann D, Goossens GH, Blaak EE, Plat J.

Chem Phys Lipids. 2017 Oct;207(Pt B):239-245. doi: 10.1016/j.chemphyslip.2017.06.006. Epub 2017 Jun 21.

PMID:
28647339
38.

Gut Microbiota and the Gut-Brain Axis: New Insights in the Pathophysiology of Metabolic Syndrome.

de Clercq NC, Frissen MN, Groen AK, Nieuwdorp M.

Psychosom Med. 2017 Oct;79(8):874-879. doi: 10.1097/PSY.0000000000000495. Review.

PMID:
28557822
39.

Developments in intestinal cholesterol transport and triglyceride absorption.

Paalvast Y, de Boer JF, Groen AK.

Curr Opin Lipidol. 2017 Jun;28(3):248-254. doi: 10.1097/MOL.0000000000000415. Review.

PMID:
28338522
40.

Transintestinal and Biliary Cholesterol Secretion Both Contribute to Macrophage Reverse Cholesterol Transport in Rats-Brief Report.

de Boer JF, Schonewille M, Dikkers A, Koehorst M, Havinga R, Kuipers F, Tietge UJ, Groen AK.

Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):643-646. doi: 10.1161/ATVBAHA.116.308558. Epub 2017 Feb 23.

PMID:
28232326
41.

Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction.

Bouter KE, van Raalte DH, Groen AK, Nieuwdorp M.

Gastroenterology. 2017 May;152(7):1671-1678. doi: 10.1053/j.gastro.2016.12.048. Epub 2017 Feb 10. Review.

PMID:
28192102
42.

Gut Microbiota in Obesity and Undernutrition.

de Clercq NC, Groen AK, Romijn JA, Nieuwdorp M.

Adv Nutr. 2016 Nov 15;7(6):1080-1089. doi: 10.3945/an.116.012914. Print 2016 Nov. Review.

43.

Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.

de Boer JF, Schonewille M, Boesjes M, Wolters H, Bloks VW, Bos T, van Dijk TH, Jurdzinski A, Boverhof R, Wolters JC, Kuivenhoven JA, van Deursen JM, Oude Elferink RPJ, Moschetta A, Kremoser C, Verkade HJ, Kuipers F, Groen AK.

Gastroenterology. 2017 Apr;152(5):1126-1138.e6. doi: 10.1053/j.gastro.2016.12.037. Epub 2017 Jan 5.

PMID:
28065787
44.

Fecal Bile Salts and the Development of Necrotizing Enterocolitis in Preterm Infants.

Hulzebos CV, van Zoonen AG, Hulscher JB, Schat TE, Kooi EM, Koehorst M, Boverhof R, Krabbe PF, Groen AK, Verkade HJ.

PLoS One. 2017 Jan 3;12(1):e0168633. doi: 10.1371/journal.pone.0168633. eCollection 2017.

45.

Maternal-fetal cholesterol transport in the second half of mouse pregnancy does not involve LDL receptor-related protein 2.

Zwier MV, Baardman ME, van Dijk TH, Jurdzinski A, Wisse LJ, Bloks VW, Berger RMF, DeRuiter MC, Groen AK, Plösch T.

Acta Physiol (Oxf). 2017 Aug;220(4):471-485. doi: 10.1111/apha.12845. Epub 2017 Feb 22.

PMID:
28024118
46.

Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders.

van Eunen K, Volker-Touw CM, Gerding A, Bleeker A, Wolters JC, van Rijt WJ, Martines AM, Niezen-Koning KE, Heiner RM, Permentier H, Groen AK, Reijngoud DJ, Derks TG, Bakker BM.

BMC Biol. 2016 Dec 7;14(1):107.

47.

Measurement of Intestinal and Peripheral Cholesterol Fluxes by a Dual-Tracer Balance Method.

Ronda OA, van Dijk TH, Verkade HJ, Groen AK.

Curr Protoc Mouse Biol. 2016 Dec 1;6(4):408-434. doi: 10.1002/cpmo.16.

PMID:
27906461
48.

Tumor Necrosis Factor-Alpha Inhibitor Etanercept Does Not Alter Methotrexate-Induced Gastrointestinal Mucositis in Rats.

Kuiken NSS, Rings EHHM, Alffenaar JC, Havinga R, Jurdzinski A, Groen AK, Tissing WJE.

J Pediatr Gastroenterol Nutr. 2017 Aug;65(2):e28-e34. doi: 10.1097/MPG.0000000000001469.

PMID:
27861204
49.

An evaluation of the therapeutic potential of fecal microbiota transplantation to treat infectious and metabolic diseases.

Groen AK, Nieuwdorp M.

EMBO Mol Med. 2017 Jan;9(1):1-3. doi: 10.15252/emmm.201607035. No abstract available.

50.

Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion.

Jakulj L, van Dijk TH, de Boer JF, Kootte RS, Schonewille M, Paalvast Y, Boer T, Bloks VW, Boverhof R, Nieuwdorp M, Beuers UH, Stroes ES, Groen AK.

Cell Metab. 2016 Dec 13;24(6):783-794. doi: 10.1016/j.cmet.2016.10.001. Epub 2016 Nov 3.

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