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Biomol NMR Assign. 2008 Dec;2(2):135-8. doi: 10.1007/s12104-008-9104-x. Epub 2008 Jul 22.

NMR assignment of the nonstructural protein nsp3(1066-1181) from SARS-CoV.

Author information

1
Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Rd., MB-44, La Jolla, CA 92037, USA.

Abstract

Sequence-specific NMR assignments of the globular core comprising the residues 1066-1181 within the non-structural protein nsp3e from the SARS coronavirus have been obtained using triple-resonance NMR experiments with the uniformly [(13)C, (15)N]-labeled protein. The backbone and side chain assignments are nearly complete, providing the basis for the ongoing NMR structure determination. A preliminary identification of regular secondary structures has been derived from the (13)C chemical shifts.

PMID:
19636888
PMCID:
PMC2776825
DOI:
10.1007/s12104-008-9104-x
[Indexed for MEDLINE]
Free PMC Article

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