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Nat Struct Biol. 2000 Nov;7 Suppl:973-7.

Automation of X-ray crystallography.

Author information

1
Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

Abstract

Structure-based biological discovery is entering a new era with the development of industrialized macromolecular structure determination pipelines. Intense, highly focused X-rays from integrated synchrotron radiation beam lines combined with significant advances in protein expression, purification, and micro-crystallization automation allow for the full streamlining of the traditionally tedious and time consuming process of determining the three dimensional structures of macromolecules.

PMID:
11104004
DOI:
10.1038/80754
[Indexed for MEDLINE]

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