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Items: 34


5-aminolevulinic acid induced protoporphyrin IX (ALA-PpIX) fluorescence guidance in meningioma surgery.

Valdes PA, Millesi M, Widhalm G, Roberts DW.

J Neurooncol. 2019 Feb;141(3):555-565. doi: 10.1007/s11060-018-03079-7. Epub 2019 Jan 2. Review.


Commentary: Extent of Resection and Residual Tumor Thresholds for Postoperative Total Seizure Freedom in Epileptic Adult Patients Harboring a Supratentorial Diffuse Low-Grade Glioma.

Valdes PA, Golby AJ.

Neurosurgery. 2018 Nov 26. doi: 10.1093/neuros/nyy527. [Epub ahead of print] No abstract available.


Volumetric analysis of magnetic resonance-guided focused ultrasound thalamotomy lesions.

Harary M, Essayed WI, Valdes PA, McDannold N, Cosgrove GR.

Neurosurg Focus. 2018 Feb;44(2):E6. doi: 10.3171/2017.11.FOCUS17587.


Focused ultrasound in neurosurgery: a historical perspective.

Harary M, Segar DJ, Huang KT, Tafel IJ, Valdes PA, Cosgrove GR.

Neurosurg Focus. 2018 Feb;44(2):E2. doi: 10.3171/2017.11.FOCUS17586.


qF-SSOP: real-time optical property corrected fluorescence imaging.

Valdes PA, Angelo JP, Choi HS, Gioux S.

Biomed Opt Express. 2017 Jul 10;8(8):3597-3605. doi: 10.1364/BOE.8.003597. eCollection 2017 Aug 1.


Readmission After Craniotomy for Tumor: A National Surgical Quality Improvement Program Analysis.

Dasenbrock HH, Yan SC, Smith TR, Valdes PA, Gormley WB, Claus EB, Dunn IF.

Neurosurgery. 2017 Apr 1;80(4):551-562. doi: 10.1093/neuros/nyw062.


Optical technologies for intraoperative neurosurgical guidance.

Valdés PA, Roberts DW, Lu FK, Golby A.

Neurosurg Focus. 2016 Mar;40(3):E8. doi: 10.3171/2015.12.FOCUS15550. Review.


Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery.

Jermyn M, Gosselin Y, Valdes PA, Sibai M, Kolste K, Mercier J, Angulo L, Roberts DW, Paulsen KD, Petrecca K, Daigle O, Wilson BC, Leblond F.

Biomed Opt Express. 2015 Nov 30;6(12):5063-74. doi: 10.1364/BOE.6.005063. eCollection 2015 Dec 1.


Quantitative fluorescence using 5-aminolevulinic acid-induced protoporphyrin IX biomarker as a surgical adjunct in low-grade glioma surgery.

Valdés PA, Jacobs V, Harris BT, Wilson BC, Leblond F, Paulsen KD, Roberts DW.

J Neurosurg. 2015 Sep;123(3):771-80. doi: 10.3171/2014.12.JNS14391. Epub 2015 Jul 3.


Macroscopic optical imaging technique for wide-field estimation of fluorescence depth in optically turbid media for application in brain tumor surgical guidance.

Kolste KK, Kanick SC, Valdés PA, Jermyn M, Wilson BC, Roberts DW, Paulsen KD, Leblond F.

J Biomed Opt. 2015 Feb;20(2):26002. doi: 10.1117/1.JBO.20.2.026002.


Higher-order CRF tumor segmentation with discriminant manifold potentials.

Kadoury S, Abi-Jaoudeh N, Valdes PA.

Med Image Comput Comput Assist Interv. 2013;16(Pt 1):719-26.


Pulsed-light imaging for fluorescence guided surgery under normal room lighting.

Sexton K, Davis SC, McClatchy D 3rd, Valdes PA, Kanick SC, Paulsen KD, Roberts DW, Pogue BW.

Opt Lett. 2013 Sep 1;38(17):3249-52. doi: 10.1364/OL.38.003249.


System and methods for wide-field quantitative fluorescence imaging during neurosurgery.

Valdes PA, Jacobs VL, Wilson BC, Leblond F, Roberts DW, Paulsen KD.

Opt Lett. 2013 Aug 1;38(15):2786-8. doi: 10.1364/OL.38.002786.


5-Aminolevulinic acid-induced protoporphyrin IX fluorescence in meningioma: qualitative and quantitative measurements in vivo.

Valdes PA, Bekelis K, Harris BT, Wilson BC, Leblond F, Kim A, Simmons NE, Erkmen K, Paulsen KD, Roberts DW.

Neurosurgery. 2014 Mar;10 Suppl 1:74-82; discussion 82-3. doi: 10.1227/NEU.0000000000000117.


Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies.

Li Y, Rey-Dios R, Roberts DW, Valdés PA, Cohen-Gadol AA.

World Neurosurg. 2014 Jul-Aug;82(1-2):175-85. doi: 10.1016/j.wneu.2013.06.014. Epub 2013 Jul 9. Review.


Quantitative, spectrally-resolved intraoperative fluorescence imaging.

Valdés PA, Leblond F, Jacobs VL, Wilson BC, Paulsen KD, Roberts DW.

Sci Rep. 2012;2:798. doi: 10.1038/srep00798. Epub 2012 Nov 12.


Adjuncts for maximizing resection: 5-aminolevuinic acid.

Roberts DW, Valdés PA, Harris BT, Hartov A, Fan X, Ji S, Pogue BW, Leblond F, Tosteson TD, Wilson BC, Paulsen KD.

Clin Neurosurg. 2012;59:75-8. Review. No abstract available.


Gadolinium- and 5-aminolevulinic acid-induced protoporphyrin IX levels in human gliomas: an ex vivo quantitative study to correlate protoporphyrin IX levels and blood-brain barrier breakdown.

Valdés PA, Moses ZB, Kim A, Belden CJ, Wilson BC, Paulsen KD, Roberts DW, Harris BT.

J Neuropathol Exp Neurol. 2012 Sep;71(9):806-13. doi: 10.1097/NEN.0b013e31826775a1.


Glioblastoma multiforme treatment with clinical trials for surgical resection (aminolevulinic acid).

Roberts DW, Valdés PA, Harris BT, Hartov A, Fan X, Ji S, Leblond F, Tosteson TD, Wilson BC, Paulsen KD.

Neurosurg Clin N Am. 2012 Jul;23(3):371-7. doi: 10.1016/ Review.


Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models.

Konecky SD, Owen CM, Rice T, Valdés PA, Kolste K, Wilson BC, Leblond F, Roberts DW, Paulsen KD, Tromberg BJ.

J Biomed Opt. 2012 May;17(5):056008. doi: 10.1117/1.JBO.17.5.056008.


Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery.

Valdés PA, Kim A, Leblond F, Conde OM, Harris BT, Paulsen KD, Wilson BC, Roberts DW.

J Biomed Opt. 2011 Nov;16(11):116007. doi: 10.1117/1.3646916.


Genetics of glioblastoma: a window into its imaging and histopathologic variability.

Belden CJ, Valdes PA, Ran C, Pastel DA, Harris BT, Fadul CE, Israel MA, Paulsen K, Roberts DW.

Radiographics. 2011 Oct;31(6):1717-40. doi: 10.1148/rg.316115512. Review.


δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy.

Valdés PA, Kim A, Brantsch M, Niu C, Moses ZB, Tosteson TD, Wilson BC, Paulsen KD, Roberts DW, Harris BT.

Neuro Oncol. 2011 Aug;13(8):846-56. doi: 10.1093/neuonc/nor086.


Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model.

Jacobs VL, Valdes PA, Hickey WF, De Leo JA.

ASN Neuro. 2011 Aug 3;3(3):e00063. doi: 10.1042/AN20110014. Review.


Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas.

Bekelis K, Valdés PA, Erkmen K, Leblond F, Kim A, Wilson BC, Harris BT, Paulsen KD, Roberts DW.

Neurosurg Focus. 2011 May;30(5):E8. doi: 10.3171/2011.2.FOCUS1112.


Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker.

Valdés PA, Leblond F, Kim A, Harris BT, Wilson BC, Fan X, Tosteson TD, Hartov A, Ji S, Erkmen K, Simmons NE, Paulsen KD, Roberts DW.

J Neurosurg. 2011 Jul;115(1):11-7. doi: 10.3171/2011.2.JNS101451. Epub 2011 Mar 25.


Confocal microscopy for the histological fluorescence pattern of a recurrent atypical meningioma: case report.

Whitson WJ, Valdes PA, Harris BT, Paulsen KD, Roberts DW.

Neurosurgery. 2011 Jun;68(6):E1768-72; discussion E1772-3. doi: 10.1227/NEU.0b013e318217163c.


Review of Neurosurgical Fluorescence Imaging Methodologies.

Pogue BW, Gibbs-Strauss S, Valdés PA, Samkoe K, Roberts DW, Paulsen KD.

IEEE J Sel Top Quantum Electron. 2010 May;16(3):493-505.


Coregistered fluorescence-enhanced tumor resection of malignant glioma: relationships between δ-aminolevulinic acid-induced protoporphyrin IX fluorescence, magnetic resonance imaging enhancement, and neuropathological parameters. Clinical article.

Roberts DW, Valdés PA, Harris BT, Fontaine KM, Hartov A, Fan X, Ji S, Lollis SS, Pogue BW, Leblond F, Tosteson TD, Wilson BC, Paulsen KD.

J Neurosurg. 2011 Mar;114(3):595-603. doi: 10.3171/2010.2.JNS091322. Epub 2010 Apr 9.


Cause-specific mortality among neurosurgeons.

Lollis SS, Valdes PA, Li Z, Ball PA, Roberts DW.

J Neurosurg. 2010 Sep;113(3):474-8. doi: 10.3171/2010.1.JNS091740.


Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications.

Leblond F, Davis SC, Valdés PA, Pogue BW.

J Photochem Photobiol B. 2010 Jan 21;98(1):77-94. doi: 10.1016/j.jphotobiol.2009.11.007. Epub 2009 Nov 26. Review.


Deferoxamine iron chelation increases delta-aminolevulinic acid induced protoporphyrin IX in xenograft glioma model.

Valdés PA, Samkoe K, O'Hara JA, Roberts DW, Paulsen KD, Pogue BW.

Photochem Photobiol. 2010 Mar-Apr;86(2):471-5. doi: 10.1111/j.1751-1097.2009.00664.x. Epub 2009 Dec 7.


Estimation of brain deformation for volumetric image updating in protoporphyrin IX fluorescence-guided resection.

Valdés PA, Fan X, Ji S, Harris BT, Paulsen KD, Roberts DW.

Stereotact Funct Neurosurg. 2010;88(1):1-10. doi: 10.1159/000258143. Epub 2009 Nov 12.


Selective incorporation of polyanionic molecules into hamster prions.

Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S.

J Biol Chem. 2007 Dec 14;282(50):36341-53. Epub 2007 Oct 16.

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