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Items: 1 to 20 of 113

1.

Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.

Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. doi: 10.1073/pnas.1603883113. Epub 2016 Jul 22.

2.

Geranylgeranylacetone, an inducer of the 70-kDa heat shock protein (HSP70), elicits unfolded protein response and coordinates cellular fate independently of HSP70.

Endo S, Hiramatsu N, Hayakawa K, Okamura M, Kasai A, Tagawa Y, Sawada N, Yao J, Kitamura M.

Mol Pharmacol. 2007 Nov;72(5):1337-48. Epub 2007 Aug 16.

PMID:
17702888
3.
4.

Quercetin affects Hsp70/IRE1α mediated protection from death induced by endoplasmic reticulum stress.

Storniolo A, Raciti M, Cucina A, Bizzarri M, Di Renzo L.

Oxid Med Cell Longev. 2015;2015:645157. doi: 10.1155/2015/645157. Epub 2015 Apr 2.

5.

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response.

Hiramatsu N, Messah C, Han J, LaVail MM, Kaufman RJ, Lin JH.

Mol Biol Cell. 2014 May;25(9):1411-20. doi: 10.1091/mbc.E13-11-0664. Epub 2014 Mar 12.

6.

Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70.

Li M, Wang J, Jing J, Hua H, Luo T, Xu L, Wang R, Liu D, Jiang Y.

J Cell Mol Med. 2009 Nov-Dec;13(11-12):4540-50. doi: 10.1111/j.1582-4934.2008.00575.x.

7.

Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response.

Sommerweiss D, Gorski T, Richter S, Garten A, Kiess W.

Biochem Biophys Res Commun. 2013 Nov 29;441(4):770-6. doi: 10.1016/j.bbrc.2013.10.130. Epub 2013 Nov 1.

8.

Targeting HSP70 and GRP78 in canine osteosarcoma cells in combination with doxorubicin chemotherapy.

Asling J, Morrison J, Mutsaers AJ.

Cell Stress Chaperones. 2016 Nov;21(6):1065-1076. Epub 2016 Sep 8.

9.

Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells.

Zu K, Bihani T, Lin A, Park YM, Mori K, Ip C.

Oncogene. 2006 Jan 26;25(4):546-54.

10.

Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells.

Sannino S, Guerriero CJ, Sabnis AJ, Stolz DB, Wallace CT, Wipf P, Watkins SC, Bivona TG, Brodsky JL.

J Cell Sci. 2018 Sep 5;131(17). pii: jcs217760. doi: 10.1242/jcs.217760.

11.

Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1.

Zhang HM, Ye X, Su Y, Yuan J, Liu Z, Stein DA, Yang D.

J Virol. 2010 Sep;84(17):8446-59. doi: 10.1128/JVI.01416-09. Epub 2010 Jun 16.

12.

Celastrol induces unfolded protein response-dependent cell death in head and neck cancer.

Fribley AM, Miller JR, Brownell AL, Garshott DM, Zeng Q, Reist TE, Narula N, Cai P, Xi Y, Callaghan MU, Kodali V, Kaufman RJ.

Exp Cell Res. 2015 Jan 15;330(2):412-22. doi: 10.1016/j.yexcr.2014.08.014. Epub 2014 Aug 17.

13.

Curcumin sensitizes acute promyelocytic leukemia cells to unfolded protein response-induced apoptosis by blocking the loss of misfolded N-CoR protein.

Ng AP, Chng WJ, Khan M.

Mol Cancer Res. 2011 Jul;9(7):878-88. doi: 10.1158/1541-7786.MCR-10-0545. Epub 2011 May 20.

14.

Hepatitis E virus ORF2 protein activates the pro-apoptotic gene CHOP and anti-apoptotic heat shock proteins.

John L, Thomas S, Herchenröder O, Pützer BM, Schaefer S.

PLoS One. 2011;6(9):e25378. doi: 10.1371/journal.pone.0025378. Epub 2011 Sep 23.

15.

Prodigiosin activates endoplasmic reticulum stress cell death pathway in human breast carcinoma cell lines.

Pan MY, Shen YC, Lu CH, Yang SY, Ho TF, Peng YT, Chang CC.

Toxicol Appl Pharmacol. 2012 Dec 15;265(3):325-34. doi: 10.1016/j.taap.2012.08.034. Epub 2012 Sep 12.

PMID:
22982536
16.

The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.

Mantuano E, Henry K, Yamauchi T, Hiramatsu N, Yamauchi K, Orita S, Takahashi K, Lin JH, Gonias SL, Campana WM.

J Neurosci. 2011 Sep 21;31(38):13376-85. doi: 10.1523/JNEUROSCI.2850-11.2011.

17.

Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.

Lust S, Vanhoecke B, VAN Gele M, Boelens J, VAN Melckebeke H, Kaileh M, Vanden Berghe W, Haegeman G, Philippé J, Bracke M, Offner F.

Anticancer Res. 2009 Oct;29(10):3797-805.

18.

A synthetic chalcone, 2'-hydroxy-2,3,5'-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells.

Lee DH, Jung Jung Y, Koh D, Lim Y, Lee YH, Shin SY.

Cancer Lett. 2016 Mar 1;372(1):1-9. doi: 10.1016/j.canlet.2015.12.017. Epub 2015 Dec 29.

PMID:
26742460
19.

PERK-eIF2α-ATF4-CHOP signaling contributes to TNFα-induced vascular calcification.

Masuda M, Miyazaki-Anzai S, Levi M, Ting TC, Miyazaki M.

J Am Heart Assoc. 2013 Sep 5;2(5):e000238. doi: 10.1161/JAHA.113.000238.

20.

Decoding cell death signals in liver inflammation.

Brenner C, Galluzzi L, Kepp O, Kroemer G.

J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. Review.

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