Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 94

1.

Midbrain dopamine neurons from hESCs.

Tomishima M.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2012 Jun 10.

2.

Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors.

Nouri N, Patel MJ, Joksimovic M, Poulin JF, Anderegg A, Taketo MM, Ma YC, Awatramani R.

Mol Cell Neurosci. 2015 Sep;68:131-42. doi: 10.1016/j.mcn.2015.07.002. Epub 2015 Jul 9.

3.

Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells.

Jaeger I, Arber C, Risner-Janiczek JR, Kuechler J, Pritzsche D, Chen IC, Naveenan T, Ungless MA, Li M.

Development. 2011 Oct;138(20):4363-74. doi: 10.1242/dev.066746. Epub 2011 Aug 31.

4.

Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.

Metzakopian E, Lin W, Salmon-Divon M, Dvinge H, Andersson E, Ericson J, Perlmann T, Whitsett JA, Bertone P, Ang SL.

Development. 2012 Jul;139(14):2625-34. doi: 10.1242/dev.081034. Epub 2012 Jun 13.

5.

Wnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis.

Joksimovic M, Awatramani R.

J Mol Cell Biol. 2014 Feb;6(1):27-33. doi: 10.1093/jmcb/mjt043. Epub 2013 Nov 28. Review.

PMID:
24287202
6.

Dopamine receptors in human embryonic stem cell neurodifferentiation.

Belinsky GS, Sirois CL, Rich MT, Short SM, Moore AR, Gilbert SE, Antic SD.

Stem Cells Dev. 2013 May 15;22(10):1522-40. doi: 10.1089/scd.2012.0150. Epub 2013 Feb 19.

7.

Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells.

Aguila JC, Blak A, van Arensbergen J, Sousa A, Vázquez N, Aduriz A, Gayosso M, Lopez Mato MP, Lopez de Maturana R, Hedlund E, Sonntag KC, Sanchez-Pernaute R.

Stem Cells Transl Med. 2014 Sep;3(9):1032-42. doi: 10.5966/sctm.2014-0011. Epub 2014 Jul 14.

8.

Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potential.

Fedele S, Collo G, Behr K, Bischofberger J, Müller S, Kunath T, Christensen K, Gündner AL, Graf M, Jagasia R, Taylor V.

Sci Rep. 2017 Jul 20;7(1):6036. doi: 10.1038/s41598-017-05633-1.

9.

Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis.

Joksimovic M, Yun BA, Kittappa R, Anderegg AM, Chang WW, Taketo MM, McKay RD, Awatramani RB.

Nat Neurosci. 2009 Feb;12(2):125-31. doi: 10.1038/nn.2243. Epub 2009 Jan 4.

PMID:
19122665
10.

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

Cooper O, Hargus G, Deleidi M, Blak A, Osborn T, Marlow E, Lee K, Levy A, Perez-Torres E, Yow A, Isacson O.

Mol Cell Neurosci. 2010 Nov;45(3):258-66. doi: 10.1016/j.mcn.2010.06.017. Epub 2010 Jul 24.

11.

Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells.

Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T.

Development. 2007 Sep;134(17):3213-25. Epub 2007 Aug 1.

12.

Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons.

Hayes L, Zhang Z, Albert P, Zervas M, Ahn S.

J Comp Neurol. 2011 Oct 15;519(15):3001-18. doi: 10.1002/cne.22711.

13.

Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells.

Denham M, Thompson LH, Leung J, Pébay A, Björklund A, Dottori M.

Stem Cells. 2010 Oct;28(10):1805-15. doi: 10.1002/stem.510.

14.

Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.

Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL.

Development. 2015 Apr 1;142(7):1315-24. doi: 10.1242/dev.115808.

15.

Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain.

Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, Kurtulmus B, Novikov O, Spatz J, Pereira G, Hübner W, Brodski C, Tucker KL, Blaess S.

Dev Biol. 2016 Jan 1;409(1):55-71. doi: 10.1016/j.ydbio.2015.10.033. Epub 2015 Nov 2.

16.

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation.

Tanabe Y, Roelink H, Jessell TM.

Curr Biol. 1995 Jun 1;5(6):651-8.

17.

hESC derived neuro-epithelial rosettes recapitulate early mammalian neurulation events; an in vitro model.

Curchoe CL, Russo J, Terskikh AV.

Stem Cell Res. 2012 Mar;8(2):239-46. doi: 10.1016/j.scr.2011.11.003. Epub 2011 Nov 20.

18.

ES cell-derived renewable and functional midbrain dopaminergic progenitors.

Chung S, Moon JI, Leung A, Aldrich D, Lukianov S, Kitayama Y, Park S, Li Y, Bolshakov VY, Lamonerie T, Kim KS.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9703-8. doi: 10.1073/pnas.1016443108. Epub 2011 May 23.

19.

BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells.

Cai J, Schleidt S, Pelta-Heller J, Hutchings D, Cannarsa G, Iacovitti L.

Dev Biol. 2013 Apr 1;376(1):62-73. doi: 10.1016/j.ydbio.2013.01.012. Epub 2013 Jan 23.

20.

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.

Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, Yang L, Beal MF, Surmeier DJ, Kordower JH, Tabar V, Studer L.

Nature. 2011 Nov 6;480(7378):547-51. doi: 10.1038/nature10648.

Supplemental Content

Support Center