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Items: 1 to 20 of 166

1.

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.

Flesken-Nikitin A, Hwang CI, Cheng CY, Michurina TV, Enikolopov G, Nikitin AY.

Nature. 2013 Mar 14;495(7440):241-5. doi: 10.1038/nature11979. Epub 2013 Mar 6.

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3.

Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas.

Clark-Knowles KV, Senterman MK, Collins O, Vanderhyden BC.

PLoS One. 2009 Dec 31;4(12):e8534. doi: 10.1371/journal.pone.0008534.

4.

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

Mullany LK, Fan HY, Liu Z, White LD, Marshall A, Gunaratne P, Anderson ML, Creighton CJ, Xin L, Deavers M, Wong KK, Richards JS.

Oncogene. 2011 Aug 11;30(32):3522-36. doi: 10.1038/onc.2011.70. Epub 2011 Mar 21.

5.

The origin of ovarian carcinomas: a unifying hypothesis.

Auersperg N.

Int J Gynecol Pathol. 2011 Jan;30(1):12-21. doi: 10.1097/PGP.0b013e3181f45f3e.

PMID:
21131839
6.

Ovarian surface epithelium as a source of ovarian cancers: unwarranted speculation or evidence-based hypothesis?

Auersperg N.

Gynecol Oncol. 2013 Jul;130(1):246-51. doi: 10.1016/j.ygyno.2013.03.021. Epub 2013 Apr 2. Review.

PMID:
23558054
7.

Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression.

Barger CJ, Zhang W, Hillman J, Stablewski AB, Higgins MJ, Vanderhyden BC, Odunsi K, Karpf AR.

Oncotarget. 2015 Sep 29;6(29):27613-27. doi: 10.18632/oncotarget.4546.

8.

Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction.

King SM, Quartuccio SM, Vanderhyden BC, Burdette JE.

Carcinogenesis. 2013 May;34(5):1125-33. doi: 10.1093/carcin/bgt003. Epub 2013 Jan 8.

PMID:
23299406
9.

Is sphere assay useful for the identification of cancer initiating cells of the ovary?

Martínez-Serrano MJ, Caballero-Baños M, Vilella R, Vidal L, Pahisa J, Martínez-Roman S.

Int J Gynecol Cancer. 2015 Jan;25(1):12-7. doi: 10.1097/IGC.0000000000000320.

PMID:
25365589
10.

Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.

Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, Kiyono T.

Carcinogenesis. 2009 Mar;30(3):423-31. doi: 10.1093/carcin/bgp007. Epub 2009 Jan 6.

PMID:
19126650
11.

FSH-FSHR3-stem cells in ovary surface epithelium: basis for adult ovarian biology, failure, aging, and cancer.

Bhartiya D, Singh J.

Reproduction. 2015 Jan;149(1):R35-48. doi: 10.1530/REP-14-0220. Epub 2014 Sep 30. Review.

12.

Ezrin overexpression by transformed human ovarian surface epithelial cells, ovarian cleft cells, and serous ovarian adenocarcinoma cells.

Fadiel A, Chen Z, Ulukus E, Ohtani K, Hatami M, Naftolin F.

Reprod Sci. 2012 Aug;19(8):797-805. doi: 10.1177/1933719111433884. Epub 2012 Apr 3.

PMID:
22477337
13.

Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells.

Motohara T, Masuko S, Ishimoto T, Yae T, Onishi N, Muraguchi T, Hirao A, Matsuzaki Y, Tashiro H, Katabuchi H, Saya H, Nagano O.

Carcinogenesis. 2011 Nov;32(11):1597-606. doi: 10.1093/carcin/bgr183. Epub 2011 Aug 8.

PMID:
21828057
14.

Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma.

Chui MH, Wang Y, Wu RC, Seidman J, Kurman RJ, Wang TL, Shih IeM.

Mod Pathol. 2015 Mar;28(3):437-45. doi: 10.1038/modpathol.2014.89. Epub 2014 Sep 12.

15.

Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse.

Wu R, Zhai Y, Kuick R, Karnezis AN, Garcia P, Naseem A, Hu TC, Fearon ER, Cho KR.

J Pathol. 2016 Nov;240(3):341-351. doi: 10.1002/path.4783.

16.

Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy.

Ren X, Wu X, Hillier SG, Fegan KS, Critchley HO, Mason JI, Sarvi S, Harlow CR.

J Steroid Biochem Mol Biol. 2015 Jun;150:54-63. doi: 10.1016/j.jsbmb.2015.03.010. Epub 2015 Mar 24.

17.

Cancerous ovarian stem cells: obscure targets for therapy but relevant to chemoresistance.

Ahmed N, Abubaker K, Findlay J, Quinn M.

J Cell Biochem. 2013 Jan;114(1):21-34. doi: 10.1002/jcb.24317. Review.

PMID:
22887554
18.

Two types of ovarian cortical inclusion cysts: proposed origin and possible role in ovarian serous carcinogenesis.

Banet N, Kurman RJ.

Int J Gynecol Pathol. 2015 Jan;34(1):3-8. doi: 10.1097/PGP.0000000000000120.

PMID:
25473746
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20.

Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells.

Bowen NJ, Walker LD, Matyunina LV, Logani S, Totten KA, Benigno BB, McDonald JF.

BMC Med Genomics. 2009 Dec 29;2:71. doi: 10.1186/1755-8794-2-71.

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