Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 125

1.

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.

Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P.

Nature. 2012 Feb 19;483(7389):350-4. doi: 10.1038/nature10798.

PMID:
22343897
2.

The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120.

Bjursell M, Xu X, Admyre T, Böttcher G, Lundin S, Nilsson R, Stone VM, Morgan NG, Lam YY, Storlien LH, Lindén D, Smith DM, Bohlooly-Y M, Oscarsson J.

PLoS One. 2014 Dec 26;9(12):e114942. doi: 10.1371/journal.pone.0114942. eCollection 2014.

3.

GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue.

Song T, Yang Y, Zhou Y, Wei H, Peng J.

Cell Mol Life Sci. 2017 Aug;74(15):2723-2733. doi: 10.1007/s00018-017-2492-2. Epub 2017 Mar 11. Review.

PMID:
28285320
4.

CD36- and GPR120-mediated Ca²⁺ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice.

Ozdener MH, Subramaniam S, Sundaresan S, Sery O, Hashimoto T, Asakawa Y, Besnard P, Abumrad NA, Khan NA.

Gastroenterology. 2014 Apr;146(4):995-1005. doi: 10.1053/j.gastro.2014.01.006. Epub 2014 Jan 9.

5.

Regulation of Energy Homeostasis via GPR120.

Ichimura A, Hara T, Hirasawa A.

Front Endocrinol (Lausanne). 2014 Jul 11;5:111. doi: 10.3389/fendo.2014.00111. eCollection 2014. Review.

6.

Free fatty acid receptor GPR120 and pathogenesis of obesity and type 2 diabetes mellitus.

Mo XL, Wei HK, Peng J, Tao YX.

Prog Mol Biol Transl Sci. 2013;114:251-76. doi: 10.1016/B978-0-12-386933-3.00007-8. Review.

PMID:
23317787
7.

Diets Containing α-Linolenic (ω3) or Oleic (ω9) Fatty Acids Rescues Obese Mice From Insulin Resistance.

Oliveira V, Marinho R, Vitorino D, Santos GA, Moraes JC, Dragano N, Sartori-Cintra A, Pereira L, Catharino RR, da Silva AS, Ropelle ER, Pauli JR, De Souza CT, Velloso LA, Cintra DE.

Endocrinology. 2015 Nov;156(11):4033-46. doi: 10.1210/en.2014-1880. Epub 2015 Aug 17.

PMID:
26280128
8.

[Diet-induced obesity and GPR120].

Ichimura A.

Nihon Rinsho. 2013 Feb;71(2):350-4. Review. Japanese.

PMID:
23631220
9.

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.

Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM.

Nat Med. 2014 Aug;20(8):942-7. doi: 10.1038/nm.3614. Epub 2014 Jul 6.

10.

Transcriptional profiling reveals a role for RORalpha in regulating gene expression in obesity-associated inflammation and hepatic steatosis.

Kang HS, Okamoto K, Takeda Y, Beak JY, Gerrish K, Bortner CD, DeGraff LM, Wada T, Xie W, Jetten AM.

Physiol Genomics. 2011 Jul 14;43(13):818-28. doi: 10.1152/physiolgenomics.00206.2010. Epub 2011 May 3.

11.

Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion.

Paulsen SJ, Larsen LK, Hansen G, Chelur S, Larsen PJ, Vrang N.

PLoS One. 2014 Feb 10;9(2):e88227. doi: 10.1371/journal.pone.0088227. eCollection 2014.

12.

Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.

Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA.

Nat Commun. 2016 Apr 21;7:11365. doi: 10.1038/ncomms11365.

13.

Hydrodynamic delivery of FGF21 gene alleviates obesity and fatty liver in mice fed a high-fat diet.

Gao M, Ma Y, Cui R, Liu D.

J Control Release. 2014 Jul 10;185:1-11. doi: 10.1016/j.jconrel.2014.03.047. Epub 2014 Apr 18.

14.

Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation.

Kalupahana NS, Claycombe K, Newman SJ, Stewart T, Siriwardhana N, Matthan N, Lichtenstein AH, Moustaid-Moussa N.

J Nutr. 2010 Nov;140(11):1915-22. doi: 10.3945/jn.110.125732. Epub 2010 Sep 22.

PMID:
20861209
15.

Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.

Suckow AT, Polidori D, Yan W, Chon S, Ma JY, Leonard J, Briscoe CP.

J Biol Chem. 2014 May 30;289(22):15751-63. doi: 10.1074/jbc.M114.568683. Epub 2014 Apr 17.

16.

Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population.

Vestmar MA, Andersson EA, Christensen CR, Hauge M, Glümer C, Linneberg A, Witte DR, Jørgensen ME, Christensen C, Brandslund I, Lauritzen T, Pedersen O, Holst B, Grarup N, Schwartz TW, Hansen T.

J Med Genet. 2016 Sep;53(9):616-23. doi: 10.1136/jmedgenet-2015-103728. Epub 2016 Apr 11.

PMID:
27068006
17.

Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease.

Morgan K, Uyuni A, Nandgiri G, Mao L, Castaneda L, Kathirvel E, French SW, Morgan TR.

Eur J Gastroenterol Hepatol. 2008 Sep;20(9):843-54. doi: 10.1097/MEG.0b013e3282f9b203.

PMID:
18794597
18.

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.

Kimura I, Ozawa K, Inoue D, Imamura T, Kimura K, Maeda T, Terasawa K, Kashihara D, Hirano K, Tani T, Takahashi T, Miyauchi S, Shioi G, Inoue H, Tsujimoto G.

Nat Commun. 2013;4:1829. doi: 10.1038/ncomms2852.

19.

Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids.

Smith U, Kahn BB.

J Intern Med. 2016 Nov;280(5):465-475. doi: 10.1111/joim.12540. Epub 2016 Oct 3. Review.

20.

Interaction between GPR120 p.R270H loss-of-function variant and dietary fat intake on incident type 2 diabetes risk in the D.E.S.I.R. study.

Lamri A, Bonnefond A, Meyre D, Balkau B, Roussel R, Marre M, Froguel P, Fumeron F; D.E.S.I.R. Study Group.

Nutr Metab Cardiovasc Dis. 2016 Oct;26(10):931-6. doi: 10.1016/j.numecd.2016.04.010. Epub 2016 Apr 25.

PMID:
27212621

Supplemental Content

Support Center