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Helicobacter pylori attenuates lipopolysaccharide-induced nitric oxide production by murine macrophages.

Lu DY, Tang CH, Chang CH, Maa MC, Fang SH, Hsu YM, Lin YH, Lin CJ, Lee WC, Lin HJ, Lee CH, Lai CH.

Innate Immun. 2012 Jun;18(3):406-17. doi: 10.1177/1753425911413164. Epub 2011 Sep 16.


Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation.

Bussière FI, Chaturvedi R, Cheng Y, Gobert AP, Asim M, Blumberg DR, Xu H, Kim PY, Hacker A, Casero RA Jr, Wilson KT.

J Biol Chem. 2005 Jan 28;280(4):2409-12. Epub 2004 Nov 17.


Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells.

Uno K, Kato K, Atsumi T, Suzuki T, Yoshitake J, Morita H, Ohara S, Kotake Y, Shimosegawa T, Yoshimura T.

Am J Physiol Gastrointest Liver Physiol. 2007 Nov;293(5):G1004-12. Epub 2007 Sep 13.


Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-kappaB in RAW 264.7 cells.

Oh JH, Lee TJ, Park JW, Kwon TK.

Eur J Pharmacol. 2008 Dec 3;599(1-3):11-7. doi: 10.1016/j.ejphar.2008.09.017. Epub 2008 Sep 24.


Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-kappaB and p38 MAP kinase activity in LPS-stimulated RAW 264.7 cells.

Kim JH, Kim DH, Baek SH, Lee HJ, Kim MR, Kwon HJ, Lee CH.

Biochem Pharmacol. 2006 Apr 14;71(8):1198-205. Epub 2006 Feb 2.


Bis-(3-hydroxyphenyl) diselenide inhibits LPS-stimulated iNOS and COX-2 expression in RAW 264.7 macrophage cells through the NF-kappaB inactivation.

Shin KM, Shen L, Park SJ, Jeong JH, Lee KT.

J Pharm Pharmacol. 2009 Apr;61(4):479-86. doi: 10.1211/jpp/61.04.0010.


Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line.

Wilson KT, Ramanujam KS, Mobley HL, Musselman RF, James SP, Meltzer SJ.

Gastroenterology. 1996 Dec;111(6):1524-33.


Inhibition of inducible nitric-oxide synthase expression by (5R)-5-hydroxytriptolide in interferon-gamma- and bacterial lipopolysaccharide-stimulated macrophages.

Zhou R, Zheng SX, Tang W, He PL, Li XY, Yang YF, Li YC, Geng JG, Zuo JP.

J Pharmacol Exp Ther. 2006 Jan;316(1):121-8. Epub 2005 Sep 15.


Flower extract of Panax notoginseng attenuates lipopolysaccharide-induced inflammatory response via blocking of NF-kappaB signaling pathway in murine macrophages.

Jung HW, Seo UK, Kim JH, Leem KH, Park YK.

J Ethnopharmacol. 2009 Mar 18;122(2):313-9. doi: 10.1016/j.jep.2008.12.024. Epub 2008 Dec 27.


Suppressive effect of novel aromatic diamine compound on nuclear factor-kappaB-dependent expression of inducible nitric oxide synthase in macrophages.

Shin HM, Byung Hak Kim, Eun Yong Chung, Jung SH, Yeong Shik Kim, Kyung Rak Min, Kim Y.

Eur J Pharmacol. 2005 Oct 3;521(1-3):1-8. Epub 2005 Sep 23.


Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.

Jung WK, Choi I, Lee DY, Yea SS, Choi YH, Kim MM, Park SG, Seo SK, Lee SW, Lee CM, Park YM, Choi IW.

Int J Biochem Cell Biol. 2008;40(11):2572-82. doi: 10.1016/j.biocel.2008.05.005. Epub 2008 May 15.


Helicobacter pylori induces macrophage apoptosis by activation of arginase II.

Gobert AP, Cheng Y, Wang JY, Boucher JL, Iyer RK, Cederbaum SD, Casero RA Jr, Newton JC, Wilson KT.

J Immunol. 2002 May 1;168(9):4692-700.


The naturally occurring biflavonoid, ochnaflavone, inhibits LPS-induced iNOS expression, which is mediated by ERK1/2 via NF-kappaB regulation, in RAW264.7 cells.

Suh SJ, Chung TW, Son MJ, Kim SH, Moon TC, Son KH, Kim HP, Chang HW, Kim CH.

Arch Biochem Biophys. 2006 Mar 15;447(2):136-46. Epub 2006 Feb 10. Erratum in: Arch Biochem Biophys. 2010 Jan 15;493(2):249.


Arginase II restricts host defense to Helicobacter pylori by attenuating inducible nitric oxide synthase translation in macrophages.

Lewis ND, Asim M, Barry DP, Singh K, de Sablet T, Boucher JL, Gobert AP, Chaturvedi R, Wilson KT.

J Immunol. 2010 Mar 1;184(5):2572-82. doi: 10.4049/jimmunol.0902436. Epub 2010 Jan 22.


Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production.

Chaturvedi R, Asim M, Hoge S, Lewis ND, Singh K, Barry DP, de Sablet T, Piazuelo MB, Sarvaria AR, Cheng Y, Closs EI, Casero RA Jr, Gobert AP, Wilson KT.

Gastroenterology. 2010 Nov;139(5):1686-98, 1698.e1-6. doi: 10.1053/j.gastro.2010.06.060. Epub 2010 Jul 1.

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