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Items: 1 to 20 of 120

1.

Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death.

Jain P, Luo ZQ, Blanke SR.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16032-7. doi: 10.1073/pnas.1105175108. Epub 2011 Sep 8.

2.

Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation.

Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T.

J Biol Chem. 2006 Apr 21;281(16):11250-9. Epub 2006 Jan 25.

3.
4.

Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death.

Wasiak S, Zunino R, McBride HM.

J Cell Biol. 2007 May 7;177(3):439-50. Epub 2007 Apr 30.

5.

Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.

Brooks C, Cho SG, Wang CY, Yang T, Dong Z.

Am J Physiol Cell Physiol. 2011 Mar;300(3):C447-55. doi: 10.1152/ajpcell.00402.2010. Epub 2010 Dec 15.

6.

Mitochondrial chaperone DnaJA3 induces Drp1-dependent mitochondrial fragmentation.

Elwi AN, Lee B, Meijndert HC, Braun JE, Kim SW.

Int J Biochem Cell Biol. 2012 Aug;44(8):1366-76. doi: 10.1016/j.biocel.2012.05.004. Epub 2012 May 15.

PMID:
22595283
7.

Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.

Parone PA, James DI, Da Cruz S, Mattenberger Y, Donzé O, Barja F, Martinou JC.

Mol Cell Biol. 2006 Oct;26(20):7397-408.

8.

6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells.

Gomez-Lazaro M, Bonekamp NA, Galindo MF, Jordán J, Schrader M.

Free Radic Biol Med. 2008 Jun 1;44(11):1960-9. doi: 10.1016/j.freeradbiomed.2008.03.009. Epub 2008 Mar 20.

PMID:
18395527
9.

Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy.

Wu S, Zhou F, Zhang Z, Xing D.

J Cell Physiol. 2011 Feb;226(2):530-41. doi: 10.1002/jcp.22362.

PMID:
20683914
10.

A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis.

Tanaka A, Youle RJ.

Mol Cell. 2008 Feb 29;29(4):409-10. doi: 10.1016/j.molcel.2008.02.005.

11.

Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis.

Estaquier J, Arnoult D.

Cell Death Differ. 2007 Jun;14(6):1086-94. Epub 2007 Mar 2.

12.

Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA.

Calore F, Genisset C, Casellato A, Rossato M, Codolo G, Esposti MD, Scorrano L, de Bernard M.

Cell Death Differ. 2010 Nov;17(11):1707-16. doi: 10.1038/cdd.2010.42. Epub 2010 Apr 30.

14.

Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis.

Wang P, Wang P, Liu B, Zhao J, Pang Q, Agrawal SG, Jia L, Liu FT.

Oncotarget. 2015 Sep 8;6(26):22598-612.

15.

Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes.

Clerc P, Ge SX, Hwang H, Waddell J, Roelofs BA, Karbowski M, Sesaki H, Polster BM.

Br J Pharmacol. 2014 Apr;171(8):1988-99. doi: 10.1111/bph.12515.

16.

N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.

Merrill RA, Slupe AM, Strack S.

FEBS J. 2013 Jan;280(2):662-73. doi: 10.1111/j.1742-4658.2012.08631.x. Epub 2012 Jun 8.

17.

Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells.

Kaddour-Djebbar I, Choudhary V, Brooks C, Ghazaly T, Lakshmikanthan V, Dong Z, Kumar MV.

Int J Oncol. 2010 Jun;36(6):1437-44.

PMID:
20428767
18.
19.

Bax translocation and mitochondrial fragmentation induced by Helicobacter pylori.

Ashktorab H, Frank S, Khaled AR, Durum SK, Kifle B, Smoot DT.

Gut. 2004 Jun;53(6):805-13.

20.

Helicobacter pylori VacA: a new perspective on an invasive chloride channel.

Rassow J, Meinecke M.

Microbes Infect. 2012 Oct;14(12):1026-33. doi: 10.1016/j.micinf.2012.07.002. Epub 2012 Jul 14. Review.

PMID:
22796385

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