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Cannabinoid receptor type 2 (CB2) deficiency alters atherosclerotic lesion formation in hyperlipidemic Ldlr-null mice.

Netherland CD, Pickle TG, Bales A, Thewke DP.

Atherosclerosis. 2010 Nov;213(1):102-8. doi: 10.1016/j.atherosclerosis.2010.07.060. Epub 2010 Aug 19.


Adipocyte enhancer-binding protein 1 (AEBP1) (a novel macrophage proinflammatory mediator) overexpression promotes and ablation attenuates atherosclerosis in ApoE (-/-) and LDLR (-/-) mice.

Bogachev O, Majdalawieh A, Pan X, Zhang L, Ro HS.

Mol Med. 2011 Sep-Oct;17(9-10):1056-64. doi: 10.2119/molmed.2011.00141. Epub 2011 Jun 14.


Discoidin domain receptor 1 (ddr1) deletion decreases atherosclerosis by accelerating matrix accumulation and reducing inflammation in low-density lipoprotein receptor-deficient mice.

Franco C, Hou G, Ahmad PJ, Fu EY, Koh L, Vogel WF, Bendeck MP.

Circ Res. 2008 May 23;102(10):1202-11. doi: 10.1161/CIRCRESAHA.107.170662. Epub 2008 May 1.


Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.

Kitamoto S, Sukhova GK, Sun J, Yang M, Libby P, Love V, Duramad P, Sun C, Zhang Y, Yang X, Peters C, Shi GP.

Circulation. 2007 Apr 17;115(15):2065-75. Epub 2007 Apr 2.


Cannabinoid Receptor Type 2 (CB2) Dependent and Independent Effects of WIN55,212-2 on Atherosclerosis in Ldlr-null Mice.

Netherland-Van Dyke C, Rodgers W, Fulmer M, Lahr Z, Thewke D.

J Cardiol Ther. 2015 Jul;3(2):53-63.


Hepatic Overexpression of Soluble Urokinase Receptor (uPAR) Suppresses Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR-/-) Mice.

Larmann J, Jurk K, Janssen H, Müller M, Herzog C, Lorenz A, Schmitz M, Nofer JR, Theilmeier G.

PLoS One. 2015 Aug 27;10(8):e0131854. doi: 10.1371/journal.pone.0131854. eCollection 2015.


Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice.

Hu L, Boesten LS, May P, Herz J, Bovenschen N, Huisman MV, Berbée JF, Havekes LM, van Vlijmen BJ, Tamsma JT.

Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2710-5. Epub 2006 Oct 12.


LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet.

Hu C, Dandapat A, Sun L, Chen J, Marwali MR, Romeo F, Sawamura T, Mehta JL.

Cardiovasc Res. 2008 Jul 15;79(2):287-93. doi: 10.1093/cvr/cvn110. Epub 2008 May 3.


Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice.

Bi X, Zhu X, Gao C, Shewale S, Cao Q, Liu M, Boudyguina E, Gebre AK, Wilson MD, Brown AL, Parks JS.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1888-99. doi: 10.1161/ATVBAHA.114.303791. Epub 2014 May 15.


Cannabinoid (CB2) receptor deficiency reduces the susceptibility of macrophages to oxidized LDL/oxysterol-induced apoptosis.

Freeman-Anderson NE, Pickle TG, Netherland CD, Bales A, Buckley NE, Thewke DP.

J Lipid Res. 2008 Nov;49(11):2338-46. doi: 10.1194/jlr.M800105-JLR200. Epub 2008 Jul 9.


Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice.

Rensing KL, de Jager SC, Stroes ES, Vos M, Twickler MT, Dallinga-Thie GM, de Vries CJ, Kuiper J, Bot I, von der Thüsen JH.

Cardiovasc Res. 2014 Feb 1;101(2):277-87. doi: 10.1093/cvr/cvt252. Epub 2013 Nov 12.


The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis.

Meurs I, Lammers B, Zhao Y, Out R, Hildebrand RB, Hoekstra M, Van Berkel TJ, Van Eck M.

Atherosclerosis. 2012 Mar;221(1):41-7. doi: 10.1016/j.atherosclerosis.2011.11.024. Epub 2011 Dec 7.


New therapy via targeting androgen receptor in monocytes/macrophages to battle atherosclerosis.

Huang CK, Pang H, Wang L, Niu Y, Luo J, Chang E, Sparks JD, Lee SO, Chang C.

Hypertension. 2014 Jun;63(6):1345-53. doi: 10.1161/HYPERTENSIONAHA.113.02804. Epub 2014 Mar 31.


Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.

Shi W, Wang X, Wong J, Hedrick CC, Wong H, Castellani LW, Lusis AJ.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):223-9.


Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice.

Willecke F, Zeschky K, Ortiz Rodriguez A, Colberg C, Auwärter V, Kneisel S, Hutter M, Lozhkin A, Hoppe N, Wolf D, von zur Mühlen C, Moser M, Hilgendorf I, Bode C, Zirlik A.

PLoS One. 2011 Apr 26;6(4):e19405. doi: 10.1371/journal.pone.0019405.


RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice.

Sun L, Ishida T, Yasuda T, Kojima Y, Honjo T, Yamamoto Y, Yamamoto H, Ishibashi S, Hirata K, Hayashi Y.

Cardiovasc Res. 2009 May 1;82(2):371-81. doi: 10.1093/cvr/cvp036. Epub 2009 Jan 28.


Low density lipoprotein receptor of macrophages facilitates atherosclerotic lesion formation in C57Bl/6 mice.

Herijgers N, Van Eck M, Groot PH, Hoogerbrugge PM, Van Berkel TJ.

Arterioscler Thromb Vasc Biol. 2000 Aug;20(8):1961-7.


Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice.

Babaev VR, Patel MB, Semenkovich CF, Fazio S, Linton MF.

J Biol Chem. 2000 Aug 25;275(34):26293-9.


Discoidin domain receptor 1 on bone marrow-derived cells promotes macrophage accumulation during atherogenesis.

Franco C, Britto K, Wong E, Hou G, Zhu SN, Chen M, Cybulsky MI, Bendeck MP.

Circ Res. 2009 Nov 20;105(11):1141-8. doi: 10.1161/CIRCRESAHA.109.207357. Epub 2009 Oct 15.


Glycogen synthase kinase 3α deficiency attenuates atherosclerosis and hepatic steatosis in high fat diet-fed low density lipoprotein receptor-deficient mice.

Banko NS, McAlpine CS, Venegas-Pino DE, Raja P, Shi Y, Khan MI, Werstuck GH.

Am J Pathol. 2014 Dec;184(12):3394-404. doi: 10.1016/j.ajpath.2014.07.028. Epub 2014 Oct 16.


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