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Heritable Thoracic Aortic Disease Overview.

Milewicz DM, Regalado E.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2003 Feb 13 [updated 2017 Dec 14].


Familial thoracic aortic aneurysms and dissections: identification of a novel locus for stable aneurysms with a low risk for progression to aortic dissection.

Guo DC, Regalado ES, Minn C, Tran-Fadulu V, Coney J, Cao J, Wang M, Yu RK, Estrera AL, Safi HJ, Shete SS, Milewicz DM.

Circ Cardiovasc Genet. 2011 Feb;4(1):36-42. doi: 10.1161/CIRCGENETICS.110.958066. Epub 2010 Dec 16.


Heritable disorders predisposing to aortic dissection.

Gleason TG.

Semin Thorac Cardiovasc Surg. 2005 Fall;17(3):274-81. Review.


Use of genetics for personalized management of heritable thoracic aortic disease: how do we get there?

Milewicz DM, Regalado ES.

J Thorac Cardiovasc Surg. 2015 Feb;149(2 Suppl):S3-5. doi: 10.1016/j.jtcvs.2014.07.070. Epub 2014 Aug 5. Review.


Endovascular repair of descending thoracic aortic aneurysm: an evidence-based analysis.

Health Quality Ontario.

Ont Health Technol Assess Ser. 2005;5(18):1-59. Epub 2005 Nov 1.


Natural history of thoracic aortic aneurysms: indications for surgery, and surgical versus nonsurgical risks.

Elefteriades JA.

Ann Thorac Surg. 2002 Nov;74(5):S1877-80; discussion S1892-8.


Familial thoracic aortic dilatations and dissections: a case control study.

Biddinger A, Rocklin M, Coselli J, Milewicz DM.

J Vasc Surg. 1997 Mar;25(3):506-11.


Reduced penetrance and variable expressivity of familial thoracic aortic aneurysms/dissections.

Milewicz DM, Chen H, Park ES, Petty EM, Zaghi H, Shashidhar G, Willing M, Patel V.

Am J Cardiol. 1998 Aug 15;82(4):474-9.


Thoracic aortic aneurysm: reading the enemy's playbook.

Elefteriades JA.

Curr Probl Cardiol. 2008 May;33(5):203-77. doi: 10.1016/j.cpcardiol.2008.01.004. Review.


Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections.

De Backer J, Renard M, Campens L, Mosquera LM, De Paepe A, Coucke P, Callewaert B, Kodolitsch Yv.

Curr Pharm Des. 2015;21(28):4061-75. Review.


Compliance with long-term surveillance recommendations following endovascular aneurysm repair or type B aortic dissection.

Kret MR, Azarbal AF, Mitchell EL, Liem TK, Landry GJ, Moneta GL.

J Vasc Surg. 2013 Jul;58(1):25-31. doi: 10.1016/j.jvs.2012.12.046. Epub 2013 Mar 7.


Thoracic aortic aneurysm clinically pertinent controversies and uncertainties.

Elefteriades JA, Farkas EA.

J Am Coll Cardiol. 2010 Mar 2;55(9):841-57. doi: 10.1016/j.jacc.2009.08.084. Review.


The genetic message of a sudden, unexpected death due to thoracic aortic dissection.

Ripperger T, Tröger HD, Schmidtke J.

Forensic Sci Int. 2009 May 30;187(1-3):1-5. doi: 10.1016/j.forsciint.2009.01.020. Epub 2009 Mar 13.


Autosomal dominant inheritance of a predisposition to thoracic aortic aneurysms and dissections and intracranial saccular aneurysms.

Regalado E, Medrek S, Tran-Fadulu V, Guo DC, Pannu H, Golabbakhsh H, Smart S, Chen JH, Shete S, Kim DH, Stern R, Braverman AC, Milewicz DM.

Am J Med Genet A. 2011 Sep;155A(9):2125-30. doi: 10.1002/ajmg.a.34050. Epub 2011 Aug 3.


S100A12 expression in thoracic aortic aneurysm is associated with increased risk of dissection and perioperative complications.

Das D, Gawdzik J, Dellefave-Castillo L, McNally EM, Husain A, Raman J, Hofmann Bowman MA.

J Am Coll Cardiol. 2012 Aug 21;60(8):775-85. doi: 10.1016/j.jacc.2012.04.027. Epub 2012 Jul 18.


Genetic and Epigenetic Regulation of Aortic Aneurysms.

Kim HW, Stansfield BK.

Biomed Res Int. 2017;2017:7268521. doi: 10.1155/2017/7268521. Epub 2017 Jan 1. Review.


Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections.

Koullias GJ, Ravichandran P, Korkolis DP, Rimm DL, Elefteriades JA.

Ann Thorac Surg. 2004 Dec;78(6):2106-10; discussion 2110-1.


Genetics of thoracic aortic aneurysm: at the crossroad of transforming growth factor-β signaling and vascular smooth muscle cell contractility.

Gillis E, Van Laer L, Loeys BL.

Circ Res. 2013 Jul 19;113(3):327-40. doi: 10.1161/CIRCRESAHA.113.300675. Review.


Complications of endovascular repair of high-risk and emergent descending thoracic aortic aneurysms and dissections.

Hansen CJ, Bui H, Donayre CE, Aziz I, Kim B, Kopchok G, Walot I, Lee J, Lippmann M, White RA.

J Vasc Surg. 2004 Aug;40(2):228-34.


Existence of abdominal aortic aneurysms in patients with thoracic aortic dissections.

Lee JJ, Dimick JB, Williams DM, Henke PK, Deeb GM, Eagle KA, Stanley JC, Upchurch GR Jr.

J Vasc Surg. 2003 Oct;38(4):671-5.

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