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Combination of hTERT knockdown and IFN-gamma treatment inhibited angiogenesis and tumor progression in glioblastoma.

George J, Banik NL, Ray SK.

Clin Cancer Res. 2009 Dec 1;15(23):7186-95. doi: 10.1158/1078-0432.CCR-09-1425. Epub 2009 Nov 24.


Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell lines.

George J, Banik NL, Ray SK.

Int J Biochem Cell Biol. 2010 Jul;42(7):1164-73. doi: 10.1016/j.biocel.2010.04.002. Epub 2010 Apr 13.


Evidence for telomerase involvement in the angiogenesis of astrocytic tumors: expression of human telomerase reverse transcriptase messenger RNA by vascular endothelial cells.

Pallini R, Pierconti F, Falchetti ML, D'Arcangelo D, Fernandez E, Maira G, D'Ambrosio E, Larocca LM.

J Neurosurg. 2001 Jun;94(6):961-71.


Knockdown of hTERT by siRNA inhibits cervical cancer cell growth in vitro and in vivo.

Shi YA, Zhao Q, Zhang LH, Du W, Wang XY, He X, Wu S, Li YL.

Int J Oncol. 2014 Sep;45(3):1216-24. doi: 10.3892/ijo.2014.2493. Epub 2014 Jun 11.


Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner.

Zhao P, Wang C, Fu Z, You Y, Cheng Y, Lu X, Lu A, Liu N, Pu P, Kang C, Salford LG, Fan X.

Int J Oncol. 2007 Aug;31(2):361-8.


Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth.

George J, Banik NL, Ray SK.

J Cell Mol Med. 2009 Oct;13(10):4205-18. doi: 10.1111/j.1582-4934.2008.00539.x.


Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.

Kargiotis O, Chetty C, Gondi CS, Tsung AJ, Dinh DH, Gujrati M, Lakka SS, Kyritsis AP, Rao JS.

Oncogene. 2008 Aug 14;27(35):4830-40. doi: 10.1038/onc.2008.122. Epub 2008 Apr 28.


Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma.

Li Y, Li M, Yao G, Geng N, Xie Y, Feng Y, Zhang P, Kong X, Xue J, Cheng S, Zhou J, Xiao L.

Cancer Gene Ther. 2011 May;18(5):318-25. doi: 10.1038/cgt.2010.81. Epub 2011 Jan 14.


Butylidenephthalide suppresses human telomerase reverse transcriptase (TERT) in human glioblastomas.

Lin PC, Lin SZ, Chen YL, Chang JS, Ho LI, Liu PY, Chang LF, Harn YC, Chen SP, Sun LY, Huang PC, Chein JT, Tsai CH, Chou CW, Harn HJ, Chiou TW.

Ann Surg Oncol. 2011 Nov;18(12):3514-27. doi: 10.1245/s10434-011-1644-0. Epub 2011 May 7.


Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma.

Ahmad F, Dixit D, Sharma V, Kumar A, Joshi SD, Sarkar C, Sen E.

Cell Death Dis. 2016 May 5;7:e2213. doi: 10.1038/cddis.2016.117.


Survivin knockdown and concurrent 4-HPR treatment controlled human glioblastoma in vitro and in vivo.

George J, Banik NL, Ray SK.

Neuro Oncol. 2010 Nov;12(11):1088-101. doi: 10.1093/neuonc/noq079. Epub 2010 Aug 2.


Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.

Lakka SS, Gondi CS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Rao JS.

Oncogene. 2004 Jun 10;23(27):4681-9.


Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis.

Yanamandra N, Gumidyala KV, Waldron KG, Gujrati M, Olivero WC, Dinh DH, Rao JS, Mohanam S.

Oncogene. 2004 Mar 18;23(12):2224-30.


hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells.

Shen Y, Zhang YW, Zhang ZX, Miao ZH, Ding J.

Cancer Biol Ther. 2008 Feb;7(2):228-36. Epub 2007 Nov 3.


Suppression of uPA and uPAR attenuates angiogenin mediated angiogenesis in endothelial and glioblastoma cell lines.

Raghu H, Lakka SS, Gondi CS, Mohanam S, Dinh DH, Gujrati M, Rao JS.

PLoS One. 2010 Aug 27;5(8):e12458. doi: 10.1371/journal.pone.0012458.


Telomerase inhibition by stable RNA interference impairs tumor growth and angiogenesis in glioblastoma xenografts.

Pallini R, Sorrentino A, Pierconti F, Maggiano N, Faggi R, Montano N, Maira G, Larocca LM, Levi A, Falchetti ML.

Int J Cancer. 2006 May 1;118(9):2158-67.


The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice.

Ezhilarasan R, Jadhav U, Mohanam I, Rao JS, Gujrati M, Mohanam S.

Int J Cancer. 2009 Jan 15;124(2):306-15. doi: 10.1002/ijc.23951.


siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells.

Dong X, Liu A, Zer C, Feng J, Zhen Z, Yang M, Zhong L.

BMC Cancer. 2009 May 5;9:133. doi: 10.1186/1471-2407-9-133.


[Inhibitory effect of silencing hTERT gene on growth of human squamous cell carcinoma xenograft in nude mice].

Yao X, Wang X, Zhang S, Yan L, Zhu H.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Oct;25(20):939-43. Chinese.


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