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Items: 1 to 20 of 95

1.

Comment on "A common genetic variant is associated with adult and childhood obesity".

Loos RJ, Barroso I, O'rahilly S, Wareham NJ.

Science. 2007 Jan 12;315(5809):187; author reply 187.

2.

Comment on "A common genetic variant is associated with adult and childhood obesity".

Dina C, Meyre D, Samson C, Tichet J, Marre M, Jouret B, Charles MA, Balkau B, Froguel P.

Science. 2007 Jan 12;315(5809):187; author reply 187.

3.

Comment on "A common genetic variant is associated with adult and childhood obesity".

Rosskopf D, Bornhorst A, Rimmbach C, Schwahn C, Kayser A, Krüger A, Tessmann G, Geissler I, Kroemer HK, Völzke H.

Science. 2007 Jan 12;315(5809):187; author reply 187.

4.

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.

Bressler J, Fornage M, Hanis CL, Kao WH, Lewis CE, McPherson R, Dent R, Mosley TH, Pennacchio LA, Boerwinkle E.

BMC Med Genet. 2009 Jun 12;10:56. doi: 10.1186/1471-2350-10-56.

5.

A common genetic variant is associated with adult and childhood obesity.

Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF.

Science. 2006 Apr 14;312(5771):279-83.

6.

Association of the common genetic variant upstream of INSIG2 gene with obesity related phenotypes in Chinese children and adolescents.

Wang HJ, Zhang H, Zhang SW, Pan YP, Ma J.

Biomed Environ Sci. 2008 Dec;21(6):528-36. doi: 10.1016/S0895-3988(09)60013-1.

PMID:
19263810
7.

Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation.

Yang L, Wu Y, Li H, Yu Z, Li X, Liu Y, Lin X, Chen Y.

Eur J Hum Genet. 2008 Jun;16(6):759-61. doi: 10.1038/ejhg.2008.8. Epub 2008 Feb 13.

8.

INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men.

Orkunoglu-Suer FE, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Harmon B, Seip RL, Hoffman EP, Devaney JM.

BMC Med Genet. 2008 Dec 23;9:117. doi: 10.1186/1471-2350-9-117.

9.

INSIG2 promoter variant, obesity markers and lipid parameters - No association in a large Slavonic Caucasian population sample.

Hubácek JA, Kuthanová L, Bohuslavová R, Adámková V, Lánská V, Meitinger T, Pfeufer A.

Folia Biol (Praha). 2010;56(3):131-4.

10.

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R.

Malzahn D, Müller-Nurasyid M, Heid IM, Wichmann HE; KORA study group, Bickeböller H.

Eur J Hum Genet. 2014 Oct;22(10):1217-24. doi: 10.1038/ejhg.2014.3. Epub 2014 Feb 12.

11.

Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).

Vimaleswaran KS, Franks PW, Brage S, Sardinha LB, Andersen LB, Wareham NJ, Ekelund U, Loos RJ.

Obesity (Silver Spring). 2009 Jul;17(7):1453-7. doi: 10.1038/oby.2008.650. Epub 2009 Feb 5.

12.

The common genetic variant upstream of INSIG2 gene is not associated with obesity in Indian population.

Kumar J, Sunkishala RR, Karthikeyan G, Sengupta S.

Clin Genet. 2007 May;71(5):415-8.

PMID:
17489846
13.

Genetic associations of the INSIG2 rs7566605 polymorphism with obesity-related metabolic traits in Malaysian Malays.

Apalasamy YD, Moy FM, Rampal S, Bulgiba A, Mohamed Z.

Genet Mol Res. 2014 Jul 4;13(3):4904-10. doi: 10.4238/2014.July.4.4.

14.

INSIG2 gene polymorphism is not associated with obesity in Caucasian, Afro-Caribbean and Indian subjects.

Smith AJ, Cooper JA, Li LK, Humphries SE.

Int J Obes (Lond). 2007 Nov;31(11):1753-5. Epub 2007 May 1.

PMID:
17471297
15.

Association of INSIG2 rs9308762 with ALT level independent of BMI.

Guan L, Shang XR, Liu FH, Song JY, Ma J, Wang HJ.

J Pediatr Gastroenterol Nutr. 2014 Feb;58(2):155-9. doi: 10.1097/MPG.0b013e3182a87b71.

PMID:
24458218
16.

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.

Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN.

PLoS Genet. 2007 Apr 27;3(4):e61. Epub 2007 Mar 7.

17.

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

Hotta K, Nakamura M, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y.

J Hum Genet. 2008;53(9):857-62. doi: 10.1007/s10038-008-0317-8. Epub 2008 Jul 10.

18.

INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study.

Talbert ME, Langefeld CD, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Obesity (Silver Spring). 2009 Aug;17(8):1554-62. doi: 10.1038/oby.2009.94. Epub 2009 Apr 9.

19.

INSIG2 G-102A promoter variant exhibits context-dependent effect on HDL-cholesterol levels but not on BMI in Caucasians.

Hubáček JA, Suchánek P, Lánská V, Piťha J, Adámková V.

Folia Biol (Praha). 2011;57(4):170-2.

20.

Lack of association between a common polymorphism near the INSIG2 gene and BMI, myocardial infarction, and cardiovascular risk factors.

Wiedmann S, Neureuther K, Stark K, Reinhard W, Kallmünzer B, Baessler A, Fischer M, Linsel-Nitschke P, Erdmann J, Schunkert H, Hengstenberg C.

Obesity (Silver Spring). 2009 Jul;17(7):1390-5. doi: 10.1038/oby.2008.669. Epub 2009 Feb 5.

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