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Items: 1 to 20 of 92

1.

A mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin.

Eckhardt M, Yaghootfam A, Fewou SN, Zöller I, Gieselmann V.

Biochem J. 2005 May 15;388(Pt 1):245-54.

2.

The human FA2H gene encodes a fatty acid 2-hydroxylase.

Alderson NL, Rembiesa BM, Walla MD, Bielawska A, Bielawski J, Hama H.

J Biol Chem. 2004 Nov 19;279(47):48562-8. Epub 2004 Aug 27.

3.

Absence of 2-hydroxylated sphingolipids is compatible with normal neural development but causes late-onset axon and myelin sheath degeneration.

Zöller I, Meixner M, Hartmann D, Büssow H, Meyer R, Gieselmann V, Eckhardt M.

J Neurosci. 2008 Sep 24;28(39):9741-54. doi: 10.1523/JNEUROSCI.0458-08.2008.

4.

Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase.

Meixner M, Jungnickel J, Grothe C, Gieselmann V, Eckhardt M.

BMC Neurosci. 2011 Mar 2;12:22. doi: 10.1186/1471-2202-12-22.

5.

FA2H-dependent fatty acid 2-hydroxylation in postnatal mouse brain.

Alderson NL, Maldonado EN, Kern MJ, Bhat NR, Hama H.

J Lipid Res. 2006 Dec;47(12):2772-80. Epub 2006 Sep 23.

6.

Reversal of non-hydroxy:alpha-hydroxy galactosylceramide ratio and unstable myelin in transgenic mice overexpressing UDP-galactose:ceramide galactosyltransferase.

Fewou SN, Büssow H, Schaeren-Wiemers N, Vanier MT, Macklin WB, Gieselmann V, Eckhardt M.

J Neurochem. 2005 Jul;94(2):469-81.

7.
8.

Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex.

Yuki D, Sugiura Y, Zaima N, Akatsu H, Hashizume Y, Yamamoto T, Fujiwara M, Sugiyama K, Setou M.

Neuroscience. 2011 Oct 13;193:44-53. doi: 10.1016/j.neuroscience.2011.07.045. Epub 2011 Jul 28.

PMID:
21802498
9.

Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation.

Uchida Y, Hama H, Alderson NL, Douangpanya S, Wang Y, Crumrine DA, Elias PM, Holleran WM.

J Biol Chem. 2007 May 4;282(18):13211-9. Epub 2007 Mar 12.

10.

FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelin.

Maldonado EN, Alderson NL, Monje PV, Wood PM, Hama H.

J Lipid Res. 2008 Jan;49(1):153-61. Epub 2007 Sep 27.

12.

Synthesis of non-hydroxy-galactosylceramides and galactosyldiglycerides by hydroxy-ceramide galactosyltransferase.

van der Bijl P, Strous GJ, Lopes-Cardozo M, Thomas-Oates J, van Meer G.

Biochem J. 1996 Jul 15;317 ( Pt 2):589-97.

13.

The Crystal Structure of an Integral Membrane Fatty Acid α-Hydroxylase.

Zhu G, Koszelak-Rosenblum M, Connelly SM, Dumont ME, Malkowski MG.

J Biol Chem. 2015 Dec 11;290(50):29820-33. doi: 10.1074/jbc.M115.680124. Epub 2015 Oct 28.

14.

2-Hydroxylated sphingomyelin profiles in cells from patients with mutated fatty acid 2-hydroxylase.

Dan P, Edvardson S, Bielawski J, Hama H, Saada A.

Lipids Health Dis. 2011 May 20;10:84. doi: 10.1186/1476-511X-10-84.

15.

Normal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glands.

Maier H, Meixner M, Hartmann D, Sandhoff R, Wang-Eckhardt L, Zöller I, Gieselmann V, Eckhardt M.

J Biol Chem. 2011 Jul 22;286(29):25922-34. doi: 10.1074/jbc.M111.231977. Epub 2011 May 31.

17.

Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system.

Yoshikawa K, Takei S, Hasegawa-Ishii S, Chiba Y, Furukawa A, Kawamura N, Hosokawa M, Woodward DF, Watanabe K, Shimada A.

Brain Res. 2011 Jan 7;1367:22-32. doi: 10.1016/j.brainres.2010.10.019. Epub 2010 Oct 13.

PMID:
20950588
18.

Molecular cloning of a chiral-specific 3 alpha-hydroxysteroid sulfotransferase.

Lee YC, Park CS, Strott CA.

J Biol Chem. 1994 Jun 3;269(22):15838-45.

19.
20.

Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers.

Guo L, Zhang X, Zhou D, Okunade AL, Su X.

J Lipid Res. 2012 Jul;53(7):1327-35. doi: 10.1194/jlr.M025742. Epub 2012 Apr 19.

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