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The major neutralizing antigenic site on herpes simplex virus glycoprotein D overlaps a receptor-binding domain.

Whitbeck JC, Muggeridge MI, Rux AH, Hou W, Krummenacher C, Lou H, van Geelen A, Eisenberg RJ, Cohen GH.

J Virol. 1999 Dec;73(12):9879-90.


Herpes simplex virus glycoprotein B binds to cell surfaces independently of heparan sulfate and blocks virus entry.

Bender FC, Whitbeck JC, Lou H, Cohen GH, Eisenberg RJ.

J Virol. 2005 Sep;79(18):11588-97.


B Virus (Macacine herpesvirus 1) Glycoprotein D Is Functional but Dispensable for Virus Entry into Macaque and Human Skin Cells.

Perelygina L, Patrusheva I, Vasireddi M, Brock N, Hilliard J.

J Virol. 2015 May;89(10):5515-24. doi: 10.1128/JVI.03568-14. Epub 2015 Mar 4.


Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection.

Brandimarti R, Huang T, Roizman B, Campadelli-Fiume G.

Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5406-10.


Herpes simplex virus glycoprotein D acquires mannose 6-phosphate residues and binds to mannose 6-phosphate receptors.

Brunetti CR, Burke RL, Kornfeld S, Gregory W, Masiarz FR, Dingwell KS, Johnson DC.

J Biol Chem. 1994 Jun 24;269(25):17067-74.


The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D.

Stiles KM, Milne RS, Cohen GH, Eisenberg RJ, Krummenacher C.

Virology. 2008 Mar 30;373(1):98-111. Epub 2008 Feb 20.


Herpes simplex virus gD and virions accumulate in endosomes by mannose 6-phosphate-dependent and -independent mechanisms.

Brunetti CR, Dingwell KS, Wale C, Graham FL, Johnson DC.

J Virol. 1998 Apr;72(4):3330-9.


Localization of the gD-binding region of the human herpes simplex virus receptor, HveA.

Whitbeck JC, Connolly SA, Willis SH, Hou W, Krummenacher C, Ponce de Leon M, Lou H, Baribaud I, Eisenberg RJ, Cohen GH.

J Virol. 2001 Jan;75(1):171-80.


Structure-based mutagenesis of herpes simplex virus glycoprotein D defines three critical regions at the gD-HveA/HVEM binding interface.

Connolly SA, Landsburg DJ, Carfi A, Wiley DC, Cohen GH, Eisenberg RJ.

J Virol. 2003 Jul;77(14):8127-40.


A double mutation in glycoprotein gB compensates for ineffective gD-dependent initiation of herpes simplex virus type 1 infection.

Uchida H, Chan J, Goins WF, Grandi P, Kumagai I, Cohen JB, Glorioso JC.

J Virol. 2010 Dec;84(23):12200-9. doi: 10.1128/JVI.01633-10. Epub 2010 Sep 22.

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