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Items: 1 to 20 of 26


Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.

Flamier A, El Hajjar J, Adjaye J, Fernandes KJ, Abdouh M, Bernier G.

Cell Rep. 2018 May 29;23(9):2653-2666. doi: 10.1016/j.celrep.2018.04.097.


INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.

Le O, Palacio L, Bernier G, Batinic-Haberle I, Hickson G, Beauséjour C.

Stem Cell Reports. 2018 Jun 5;10(6):1721-1733. doi: 10.1016/j.stemcr.2018.03.025. Epub 2018 Apr 26.


The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to β-amyloid peptide.

Lanchec E, Désilets A, Béliveau F, Flamier A, Mahmoud S, Bernier G, Gris D, Leduc R, Lavoie C.

J Biol Chem. 2017 Dec 15;292(50):20669-20682. doi: 10.1074/jbc.M117.792911. Epub 2017 Oct 20.


Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.

Barabino A, Plamondon V, Abdouh M, Chatoo W, Flamier A, Hanna R, Zhou S, Motoyama N, Hébert M, Lavoie J, Bernier G.

Development. 2016 May 1;143(9):1571-84. doi: 10.1242/dev.125351. Epub 2016 Mar 10.


The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells.

Abdouh M, Hanna R, El Hajjar J, Flamier A, Bernier G.

J Biol Chem. 2016 Jan 1;291(1):182-97. doi: 10.1074/jbc.M115.662403. Epub 2015 Oct 14.


Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling.

Zhou S, Flamier A, Abdouh M, Tétreault N, Barabino A, Wadhwa S, Bernier G.

Development. 2015 Oct 1;142(19):3294-306. doi: 10.1242/dev.125385.


ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo.

Wilson AM, Morquette B, Abdouh M, Unsain N, Barker PA, Feinstein E, Bernier G, Di Polo A.

J Neurosci. 2013 Jan 30;33(5):2205-16. doi: 10.1523/JNEUROSCI.2635-12.2013.


Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons.

Abdouh M, Chatoo W, El Hajjar J, David J, Ferreira J, Bernier G.

PLoS One. 2012;7(2):e31870. doi: 10.1371/journal.pone.0031870. Epub 2012 Feb 23.


Brain cancer stem cells: current status on glioblastoma multiforme.

Facchino S, Abdouh M, Bernier G.

Cancers (Basel). 2011 Mar 30;3(2):1777-97. doi: 10.3390/cancers3021777.


p53 pro-oxidant activity in the central nervous system: implication in aging and neurodegenerative diseases.

Chatoo W, Abdouh M, Bernier G.

Antioxid Redox Signal. 2011 Sep 15;15(6):1729-37. doi: 10.1089/ars.2010.3610. Epub 2011 Mar 31. Review.


BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery.

Facchino S, Abdouh M, Chatoo W, Bernier G.

J Neurosci. 2010 Jul 28;30(30):10096-111. doi: 10.1523/JNEUROSCI.1634-10.2010.


BMI1 sustains human glioblastoma multiforme stem cell renewal.

Abdouh M, Facchino S, Chatoo W, Balasingam V, Ferreira J, Bernier G.

J Neurosci. 2009 Jul 15;29(28):8884-96. doi: 10.1523/JNEUROSCI.0968-09.2009.


The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation.

Tétreault N, Champagne MP, Bernier G.

Dev Biol. 2009 Mar 15;327(2):541-50. doi: 10.1016/j.ydbio.2008.12.022. Epub 2008 Dec 30.


The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity.

Chatoo W, Abdouh M, David J, Champagne MP, Ferreira J, Rodier F, Bernier G.

J Neurosci. 2009 Jan 14;29(2):529-42. doi: 10.1523/JNEUROSCI.5303-08.2009.


Pax6 controls the proliferation rate of neuroepithelial progenitors from the mouse optic vesicle.

Duparc RH, Abdouh M, David J, Lépine M, Tétreault N, Bernier G.

Dev Biol. 2007 Jan 15;301(2):374-87. Epub 2006 Nov 10.


Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice.

Duparc RH, Boutemmine D, Champagne MP, Tétreault N, Bernier G.

Dev Biol. 2006 Dec 15;300(2):647-55. Epub 2006 Aug 9.


Identification of genes expressed in retinal progenitor/stem cell colonies isolated from the ocular ciliary body of adult mice.

Lord-Grignon J, Abdouh M, Bernier G.

Gene Expr Patterns. 2006 Oct;6(8):992-9. Epub 2006 Jun 9.


In vivo reactivation of a quiescent cell population located in the ocular ciliary body of adult mammals.

Abdouh M, Bernier G.

Exp Eye Res. 2006 Jul;83(1):153-64. Epub 2006 Mar 23.


Genetic alterations at the Bpag1 locus in dt mice and their impact on transcript expression.

Pool M, Boudreau Larivière C, Bernier G, Young KG, Kothary R.

Mamm Genome. 2005 Dec;16(12):909-17. Epub 2005 Dec 8.


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