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Items: 1 to 20 of 182

1.

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J.

NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018.

2.

Protein Interactomics by Two-Hybrid Methods.

Choi SG, Richardson A, Lambourne L, Hill DE, Vidal M.

Methods Mol Biol. 2018;1794:1-14. doi: 10.1007/978-1-4939-7871-7_1.

PMID:
29855947
3.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

PMID:
29443976
4.

Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes.

Martínez-Noël G, Luck K, Kühnle S, Desbuleux A, Szajner P, Galligan JT, Rodriguez D, Zheng L, Boyland K, Leclere F, Zhong Q, Hill DE, Vidal M, Howley PM.

J Mol Biol. 2018 Mar 30;430(7):1024-1050. doi: 10.1016/j.jmb.2018.01.021. Epub 2018 Feb 6.

PMID:
29426014
5.

A framework for exhaustively mapping functional missense variants.

Weile J, Sun S, Cote AG, Knapp J, Verby M, Mellor JC, Wu Y, Pons C, Wong C, van Lieshout N, Yang F, Tasan M, Tan G, Yang S, Fowler DM, Nussbaum R, Bloom JD, Vidal M, Hill DE, Aloy P, Roth FP.

Mol Syst Biol. 2017 Dec 21;13(12):957. doi: 10.15252/msb.20177908.

6.

Challenges and recommendations for epigenomics in precision health.

Carter AC, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ, Hacohen N, He C, Hill D, Ko J, Kohane I, Kundaje A, Palmer M, Snyder MP, Tung J, Urban A, Vidal M, Wong W.

Nat Biotechnol. 2017 Dec 8;35(12):1128-1132. doi: 10.1038/nbt.4030. No abstract available.

7.

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing.

Ghadie MA, Lambourne L, Vidal M, Xia Y.

PLoS Comput Biol. 2017 Aug 28;13(8):e1005717. doi: 10.1371/journal.pcbi.1005717. eCollection 2017 Aug.

8.

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target.

Jo M, Chung AY, Yachie N, Seo M, Jeon H, Nam Y, Seo Y, Kim E, Zhong Q, Vidal M, Park HC, Roth FP, Suk K.

Genome Res. 2017 Sep;27(9):1487-1500. doi: 10.1101/gr.211649.116. Epub 2017 Jun 8.

9.

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits.

Yao C, Joehanes R, Johnson AD, Huan T, Liu C, Freedman JE, Munson PJ, Hill DE, Vidal M, Levy D.

Am J Hum Genet. 2017 Jun 1;100(6):985-986. doi: 10.1016/j.ajhg.2017.05.002. No abstract available.

10.

Identifying pathogenicity of human variants via paralog-based yeast complementation.

Yang F, Sun S, Tan G, Costanzo M, Hill DE, Vidal M, Andrews BJ, Boone C, Roth FP.

PLoS Genet. 2017 May 25;13(5):e1006779. doi: 10.1371/journal.pgen.1006779. eCollection 2017 May.

11.

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits.

Yao C, Joehanes R, Johnson AD, Huan T, Liu C, Freedman JE, Munson PJ, Hill DE, Vidal M, Levy D.

Am J Hum Genet. 2017 Apr 6;100(4):571-580. doi: 10.1016/j.ajhg.2017.02.003. Epub 2017 Mar 9. Erratum in: Am J Hum Genet. 2017 Jun 1;100(6):985-986.

12.

Proteome-Scale Human Interactomics.

Luck K, Sheynkman GM, Zhang I, Vidal M.

Trends Biochem Sci. 2017 May;42(5):342-354. doi: 10.1016/j.tibs.2017.02.006. Epub 2017 Mar 8. Review.

13.

HSP90 Shapes the Consequences of Human Genetic Variation.

Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S.

Cell. 2017 Feb 23;168(5):856-866.e12. doi: 10.1016/j.cell.2017.01.023. Epub 2017 Feb 16.

14.

In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.

Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):242-250.e4. doi: 10.1016/j.cels.2017.01.002. Epub 2017 Jan 25.

15.

Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.

Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):157-170.e14. doi: 10.1016/j.cels.2016.12.011. Epub 2017 Jan 25.

16.

General Practitioners' Clinical Impression in the Screening for Frailty: Data From the FAP Study Pilot.

Fougère B, Sirois MJ, Carmichael PH, Batomen-Kuimi BL, Chicoulaa B, Escourrou E, Nourhashémi F, Oustric S, Vellas B; FAP group.

J Am Med Dir Assoc. 2017 Feb 1;18(2):193.e1-193.e5. doi: 10.1016/j.jamda.2016.11.008.

PMID:
28126138
17.

Proteome-scale Binary Interactomics in Human Cells.

Lievens S, Van der Heyden J, Masschaele D, De Ceuninck L, Petta I, Gupta S, De Puysseleyr V, Vauthier V, Lemmens I, De Clercq DJ, Defever D, Vanderroost N, De Smet AS, Eyckerman S, Van Calenbergh S, Martens L, De Bosscher K, Libert C, Hill DE, Vidal M, Tavernier J.

Mol Cell Proteomics. 2016 Dec;15(12):3624-3639. Epub 2016 Nov 1.

18.

Playing Hide-and-Seek with Yeast.

Vidal M.

Cell. 2016 Aug 25;166(5):1069-1073. doi: 10.1016/j.cell.2016.08.018. No abstract available.

19.

Mapping transcription factor interactome networks using HaloTag protein arrays.

Yazaki J, Galli M, Kim AY, Nito K, Aleman F, Chang KN, Carvunis AR, Quan R, Nguyen H, Song L, Alvarez JM, Huang SS, Chen H, Ramachandran N, Altmann S, Gutiérrez RA, Hill DE, Schroeder JI, Chory J, LaBaer J, Vidal M, Braun P, Ecker JR.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4238-47. doi: 10.1073/pnas.1603229113. Epub 2016 Jun 29.

20.

The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.

Rambout X, Detiffe C, Bruyr J, Mariavelle E, Cherkaoui M, Brohée S, Demoitié P, Lebrun M, Soin R, Lesage B, Guedri K, Beullens M, Bollen M, Farazi TA, Kettmann R, Struman I, Hill DE, Vidal M, Kruys V, Simonis N, Twizere JC, Dequiedt F.

Nat Struct Mol Biol. 2016 Jul;23(7):663-72. doi: 10.1038/nsmb.3243. Epub 2016 Jun 6.

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