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Items: 1 to 20 of 681

1.

Comparison of Nicotine and Toxicant Exposure in Users of Electronic Cigarettes and Combustible Cigarettes.

Goniewicz ML, Smith DM, Edwards KC, Blount BC, Caldwell KL, Feng J, Wang L, Christensen C, Ambrose B, Borek N, van Bemmel D, Konkel K, Erives G, Stanton CA, Lambert E, Kimmel HL, Hatsukami D, Hecht SS, Niaura RS, Travers M, Lawrence C, Hyland AJ.

JAMA Netw Open. 2018 Dec 7;1(8):e185937. doi: 10.1001/jamanetworkopen.2018.5937.

PMID:
30646298
2.

Analysis of acrolein-derived 1, N2-propanodeoxyguanosine adducts in human lung DNA from smokers and non-smokers.

Yang J, Balbo S, Villalta PW, Hecht SS.

Chem Res Toxicol. 2019 Jan 15. doi: 10.1021/acs.chemrestox.8b00326. [Epub ahead of print]

PMID:
30644728
3.

Prediagnostic levels of urinary 8-epi-prostaglandin F2α and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma.

Yuan JM, Grouls M, Carmella SG, Wang R, Heskin A, Jiang Y, Tan YT, Adams-Haduch J, Gao YT, Hecht SS.

Carcinogenesis. 2019 Jan 5. doi: 10.1093/carcin/bgy180. [Epub ahead of print]

PMID:
30615102
4.

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein.

Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS.

PLoS One. 2019 Jan 4;14(1):e0210104. doi: 10.1371/journal.pone.0210104. eCollection 2019.

5.

Urinary concentrations of monohydroxylated polycyclic aromatic hydrocarbons in adults from the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014).

Wang Y, Wong LY, Meng L, Pittman EN, Trinidad DA, Hubbard KL, Etheredge A, Del Valle-Pinero AY, Zamoiski R, van Bemmel DM, Borek N, Patel V, Kimmel HL, Conway KP, Lawrence C, Edwards KC, Hyland A, Goniewicz ML, Hatsukami D, Hecht SS, Calafat AM.

Environ Int. 2019 Feb;123:201-208. doi: 10.1016/j.envint.2018.11.068. Epub 2018 Dec 6.

6.

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Bastaki M, Davidsen JM, Harman CL, McGowen M, Taylor SV.

Food Chem Toxicol. 2018 Nov 24;124:192-218. doi: 10.1016/j.fct.2018.11.052. [Epub ahead of print]

7.

Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.

Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC.

JAMA. 2018 Sep 4;320(9):880-891. doi: 10.1001/jama.2018.11473.

PMID:
30193275
8.

Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers.

Murphy SE, Park SL, Balbo S, Haiman CA, Hatsukami DK, Patel Y, Peterson LA, Stepanov I, Stram DO, Tretyakova N, Hecht SS, Le Marchand L.

NPJ Precis Oncol. 2018 Aug 22;2:17. doi: 10.1038/s41698-018-0057-y. eCollection 2018. Review.

9.

The safety evaluation of food flavouring substances: the role of metabolic studies.

Smith RL, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Guengerich FP, Rietjens IMCM, Bastaki M, Harman CL, McGowen MM, Taylor SV.

Toxicol Res (Camb). 2018 Mar 28;7(4):618-646. doi: 10.1039/c7tx00254h. eCollection 2018 Jul 1. Review.

PMID:
30090611
10.

Relationship of the oxidative damage biomarker 8-epi-prostaglandin F2α to risk of lung cancer development in the Shanghai Cohort Study.

Yuan JM, Carmella SG, Wang R, Tan YT, Adams-Haduch J, Gao YT, Hecht SS.

Carcinogenesis. 2018 Jul 3;39(7):948-954. doi: 10.1093/carcin/bgy060.

PMID:
29726912
12.
13.

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Davidsen JM, Harman CL, Taylor SV.

Food Chem Toxicol. 2018 Mar;113:171-178. doi: 10.1016/j.fct.2018.01.021. Epub 2018 Jan 31.

14.

A New Editorial Team for CRT.

Hecht SS.

Chem Res Toxicol. 2018 Jan 16;31(1):1. doi: 10.1021/acs.chemrestox.7b00318. Epub 2017 Dec 28. No abstract available.

PMID:
29283558
15.

Identification and analysis of a mercapturic acid conjugate of indole-3-methyl isothiocyanate in the urine of humans who consumed cruciferous vegetables.

Upadhyaya P, Zarth AT, Fujioka N, Fritz VA, Hecht SS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:341-346. doi: 10.1016/j.jchromb.2017.12.001. Epub 2017 Dec 2.

16.

Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.

Carcinogenesis. 2018 Feb 9;39(2):232-241. doi: 10.1093/carcin/bgx135.

PMID:
29194532
17.
18.

Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.

Chem Res Toxicol. 2018 Jan 16;31(1):48-57. doi: 10.1021/acs.chemrestox.7b00281. Epub 2017 Nov 30.

19.

Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung.

Villalta PW, Hochalter JB, Hecht SS.

Anal Chem. 2017 Dec 5;89(23):12735-12742. doi: 10.1021/acs.analchem.7b02856. Epub 2017 Nov 17.

20.

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s.

Carlson ES, Upadhyaya P, Hecht SS.

J Vis Exp. 2017 Sep 25;(127). doi: 10.3791/56312.

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