Format
Sort by
Items per page

Send to

Choose Destination

Best matches for Garcia+KC:

Search results

Items: 1 to 20 of 210

1.

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.

Mohan K, Ueda G, Kim AR, Jude KM, Fallas JA, Guo Y, Hafer M, Miao Y, Saxton RA, Piehler J, Sankaran VG, Baker D, Garcia KC.

Science. 2019 May 24;364(6442). pii: eaav7532. doi: 10.1126/science.aav7532. Epub 2019 May 23.

PMID:
31123111
2.

Receptor subtype discrimination using extensive shape complementary designed interfaces.

Dang LT, Miao Y, Ha A, Yuki K, Park K, Janda CY, Jude KM, Mohan K, Ha N, Vallon M, Yuan J, Vilches-Moure JG, Kuo CJ, Garcia KC, Baker D.

Nat Struct Mol Biol. 2019 Jun;26(6):407-414. doi: 10.1038/s41594-019-0224-z. Epub 2019 May 13.

PMID:
31086346
3.

Structure of the IFNγ receptor complex guides design of biased agonists.

Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC.

Nature. 2019 Mar;567(7746):56-60. doi: 10.1038/s41586-019-0988-7. Epub 2019 Feb 27.

PMID:
30814731
4.

De novo design of potent and selective mimics of IL-2 and IL-15.

Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labão-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, Pardo-Avila F, Castellanos J, Carter L, Stewart L, Riddell SR, Pepper M, Bernardes GJL, Dougan M, Garcia KC, Baker D.

Nature. 2019 Jan;565(7738):186-191. doi: 10.1038/s41586-018-0830-7. Epub 2019 Jan 9.

PMID:
30626941
5.

Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance.

Pervolaraki K, Rastgou Talemi S, Albrecht D, Bormann F, Bamford C, Mendoza JL, Garcia KC, McLauchlan J, Höfer T, Stanifer ML, Boulant S.

PLoS Pathog. 2018 Nov 28;14(11):e1007420. doi: 10.1371/journal.ppat.1007420. eCollection 2018 Nov.

6.

A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.

Bamford CGG, Aranday-Cortes E, Filipe IC, Sukumar S, Mair D, Filipe ADS, Mendoza JL, Garcia KC, Fan S, Tishkoff SA, McLauchlan J.

PLoS Pathog. 2018 Oct 11;14(10):e1007307. doi: 10.1371/journal.ppat.1007307. eCollection 2018 Oct.

7.

A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability.

Vallon M, Yuki K, Nguyen TD, Chang J, Yuan J, Siepe D, Miao Y, Essler M, Noda M, Garcia KC, Kuo CJ.

Cell Rep. 2018 Oct 9;25(2):339-349.e9. doi: 10.1016/j.celrep.2018.09.045.

8.

T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability.

Riley TP, Hellman LM, Gee MH, Mendoza JL, Alonso JA, Foley KC, Nishimura MI, Vander Kooi CW, Garcia KC, Baker BM.

Nat Chem Biol. 2018 Oct;14(10):934-942. doi: 10.1038/s41589-018-0130-4. Epub 2018 Sep 17.

9.

Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy.

Spangler JB, Trotta E, Tomala J, Peck A, Young TA, Savvides CS, Silveria S, Votavova P, Salafsky J, Pande VS, Kovar M, Bluestone JA, Garcia KC.

J Immunol. 2018 Oct 1;201(7):2094-2106. doi: 10.4049/jimmunol.1800578. Epub 2018 Aug 13.

PMID:
30104245
10.

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, Goddard WA 3rd, Heath JR, Evavold BD, Vale RD, Garcia KC.

Cell. 2018 Jul 26;174(3):672-687.e27. doi: 10.1016/j.cell.2018.06.017.

PMID:
30053426
11.

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.

Gee MH, Sibener LV, Birnbaum ME, Jude KM, Yang X, Fernandes RA, Mendoza JL, Glassman CR, Garcia KC.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7369-E7378. doi: 10.1073/pnas.1802746115. Epub 2018 Jul 18.

12.

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.

Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA.

Nat Med. 2018 Jul;24(7):1005-1014. doi: 10.1038/s41591-018-0070-2. Epub 2018 Jun 25.

13.

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

Miles TF, Spiess K, Jude KM, Tsutsumi N, Burg JS, Ingram JR, Waghray D, Hjorto GM, Larsen O, Ploegh HL, Rosenkilde MM, Garcia KC.

Elife. 2018 Jun 8;7. pii: e35850. doi: 10.7554/eLife.35850.

14.

Deepening Attention to Social Location in Building Leader and Leadership Efficacy.

Turman NT, Garcia KCA, Howes S.

New Dir Stud Leadersh. 2018 Sep;2018(159):65-76. doi: 10.1002/yd.20298.

PMID:
29864233
15.

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.

Fraietta JA, Nobles CL, Sammons MA, Lundh S, Carty SA, Reich TJ, Cogdill AP, Morrissette JJD, DeNizio JE, Reddy S, Hwang Y, Gohil M, Kulikovskaya I, Nazimuddin F, Gupta M, Chen F, Everett JK, Alexander KA, Lin-Shiao E, Gee MH, Liu X, Young RM, Ambrose D, Wang Y, Xu J, Jordan MS, Marcucci KT, Levine BL, Garcia KC, Zhao Y, Kalos M, Porter DL, Kohli RM, Lacey SF, Berger SL, Bushman FD, June CH, Melenhorst JJ.

Nature. 2018 Jun;558(7709):307-312. doi: 10.1038/s41586-018-0178-z. Epub 2018 May 30.

16.

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC.

Science. 2018 Mar 2;359(6379):1037-1042. doi: 10.1126/science.aar3246.

17.

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.

Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC.

Cell. 2018 Jan 25;172(3):549-563.e16. doi: 10.1016/j.cell.2017.11.043. Epub 2017 Dec 21.

18.

Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.

Chheda ZS, Kohanbash G, Okada K, Jahan N, Sidney J, Pecoraro M, Yang X, Carrera DA, Downey KM, Shrivastav S, Liu S, Lin Y, Lagisetti C, Chuntova P, Watchmaker PB, Mueller S, Pollack IF, Rajalingam R, Carcaboso AM, Mann M, Sette A, Garcia KC, Hou Y, Okada H.

J Exp Med. 2018 Jan 2;215(1):141-157. doi: 10.1084/jem.20171046. Epub 2017 Dec 4.

19.

Inhibition of Delta-induced Notch signaling using fucose analogs.

Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS.

Nat Chem Biol. 2018 Jan;14(1):65-71. doi: 10.1038/nchembio.2520. Epub 2017 Nov 27.

20.

In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.

Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9338-E9345. doi: 10.1073/pnas.1710358114. Epub 2017 Oct 17.

Supplemental Content

Loading ...
Support Center