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Items: 1 to 20 of 149


Complement Membrane Attack Complexes Assemble NLRP3 Inflammasomes Triggering IL-1 Activation of IFN-γ-Primed Human Endothelium.

Xie CB, Qin L, Li G, Fang C, Kirkiles-Smith NC, Tellides G, Pober JS, Jane-Wit D.

Circ Res. 2019 Jun 7;124(12):1747-1759. doi: 10.1161/CIRCRESAHA.119.314845. Epub 2019 Apr 22.


Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation.

Ramírez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C.

Circulation. 2019 Jul 16;140(3):225-239. doi: 10.1161/CIRCULATIONAHA.118.038571. Epub 2019 Jun 3.


ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.

Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D.

Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2.


Fas ligand and nitric oxide combination to control smooth muscle growth while sparing endothelium.

Kural MH, Wang J, Gui L, Yuan Y, Li G, Leiby KL, Quijano E, Tellides G, Saltzman WM, Niklason LE.

Biomaterials. 2019 Aug;212:28-38. doi: 10.1016/j.biomaterials.2019.05.011. Epub 2019 May 7.


Multimodality Imaging Involving Magnetic Resonance Facilitates Giant Symptomatic Myxoma Resection.

Hur DJ, Prescher LM, Meadows JL, Pfau SE, Homer RJ, Tellides G, Yun JJ.

Ann Thorac Surg. 2019 Jan;107(1):e15-e17. doi: 10.1016/j.athoracsur.2018.05.083. Epub 2018 Jul 2.


Central artery stiffness and thoracic aortopathy.

Humphrey JD, Tellides G.

Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H169-H182. doi: 10.1152/ajpheart.00205.2018. Epub 2018 Nov 9.


Combining in vivo and in vitro biomechanical data reveals key roles of perivascular tethering in central artery function.

Ferruzzi J, Di Achille P, Tellides G, Humphrey JD.

PLoS One. 2018 Sep 7;13(9):e0201379. doi: 10.1371/journal.pone.0201379. eCollection 2018.


Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells.

Misra A, Feng Z, Chandran RR, Kabir I, Rotllan N, Aryal B, Sheikh AQ, Ding L, Qin L, Fernández-Hernando C, Tellides G, Greif DM.

Nat Commun. 2018 May 25;9(1):2073. doi: 10.1038/s41467-018-04447-7.


Compromised mechanical homeostasis in arterial aging and associated cardiovascular consequences.

Ferruzzi J, Madziva D, Caulk AW, Tellides G, Humphrey JD.

Biomech Model Mechanobiol. 2018 Oct;17(5):1281-1295. doi: 10.1007/s10237-018-1026-7. Epub 2018 May 12.


Further Evidence Supporting a Protective Role of Transforming Growth Factor-β (TGFβ) in Aortic Aneurysm and Dissection.

Tellides G.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):1983-1986. doi: 10.1161/ATVBAHA.117.310031. No abstract available.


Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering.

Luo J, Qin L, Kural MH, Schwan J, Li X, Bartulos O, Cong XQ, Ren Y, Gui L, Li G, Ellis MW, Li P, Kotton DN, Dardik A, Pober JS, Tellides G, Rolle M, Campbell S, Hawley RJ, Sachs DH, Niklason LE, Qyang Y.

Biomaterials. 2017 Dec;147:116-132. doi: 10.1016/j.biomaterials.2017.09.019. Epub 2017 Sep 19.


Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells.

Cui J, Qin L, Zhang J, Abrahimi P, Li H, Li G, Tietjen GT, Tellides G, Pober JS, Mark Saltzman W.

Nat Commun. 2017 Aug 4;8(1):191. doi: 10.1038/s41467-017-00297-x.


mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice.

Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, Qyang Y, Greif DM, Geirsson A, Humphrey JD, Tellides G.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1657-1666. doi: 10.1161/ATVBAHA.117.309653. Epub 2017 Jul 27.


Improving in vivo outcomes of decellularized vascular grafts via incorporation of a novel extracellular matrix.

Kristofik NJ, Qin L, Calabro NE, Dimitrievska S, Li G, Tellides G, Niklason LE, Kyriakides TR.

Biomaterials. 2017 Oct;141:63-73. doi: 10.1016/j.biomaterials.2017.06.025. Epub 2017 Jun 22.


The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis.

Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, Song L, Zhou X, Chen J, Zhou H, Zhang H, Tellides G, Min W, Yu L.

Nat Commun. 2017 Jun 1;8:15426. doi: 10.1038/ncomms15426.


Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms.

Bellini C, Bersi MR, Caulk AW, Ferruzzi J, Milewicz DM, Ramirez F, Rifkin DB, Tellides G, Yanagisawa H, Humphrey JD.

J R Soc Interface. 2017 May;14(130). pii: 20161036. doi: 10.1098/rsif.2016.1036.


Deficient Circumferential Growth Is the Primary Determinant of Aortic Obstruction Attributable to Partial Elastin Deficiency.

Jiao Y, Li G, Korneva A, Caulk AW, Qin L, Bersi MR, Li Q, Li W, Mecham RP, Humphrey JD, Tellides G.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):930-941. doi: 10.1161/ATVBAHA.117.309079. Epub 2017 Mar 2.


Biomechanical Phenotyping of the Murine Aorta: What Is the Best Control?

Bellini C, Caulk AW, Li G, Tellides G, Humphrey JD.

J Biomech Eng. 2017 Apr 1;139(4). doi: 10.1115/1.4035551.


Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.

Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):328-340. doi: 10.1161/ATVBAHA.116.308507. Epub 2016 Nov 10.


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