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Items: 1 to 20 of 142


Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells.

Misra A, Feng Z, Chandran RR, Kabir I, Rotllan N, Aryal B, Sheikh AQ, Ding L, Qin L, Fernández-Hernando C, Tellides G, Greif DM.

Nat Commun. 2018 May 25;9(1):2073. doi: 10.1038/s41467-018-04447-7.


Compromised mechanical homeostasis in arterial aging and associated cardiovascular consequences.

Ferruzzi J, Madziva D, Caulk AW, Tellides G, Humphrey JD.

Biomech Model Mechanobiol. 2018 May 12. doi: 10.1007/s10237-018-1026-7. [Epub ahead of print]


Further Evidence Supporting a Protective Role of Transforming Growth Factor-β (TGFβ) in Aortic Aneurysm and Dissection.

Tellides G.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):1983-1986. doi: 10.1161/ATVBAHA.117.310031. No abstract available.


Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering.

Luo J, Qin L, Kural MH, Schwan J, Li X, Bartulos O, Cong XQ, Ren Y, Gui L, Li G, Ellis MW, Li P, Kotton DN, Dardik A, Pober JS, Tellides G, Rolle M, Campbell S, Hawley RJ, Sachs DH, Niklason LE, Qyang Y.

Biomaterials. 2017 Dec;147:116-132. doi: 10.1016/j.biomaterials.2017.09.019. Epub 2017 Sep 19.


Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells.

Cui J, Qin L, Zhang J, Abrahimi P, Li H, Li G, Tietjen GT, Tellides G, Pober JS, Mark Saltzman W.

Nat Commun. 2017 Aug 4;8(1):191. doi: 10.1038/s41467-017-00297-x.


mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice.

Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, Qyang Y, Greif DM, Geirsson A, Humphrey JD, Tellides G.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1657-1666. doi: 10.1161/ATVBAHA.117.309653. Epub 2017 Jul 27.


Improving in vivo outcomes of decellularized vascular grafts via incorporation of a novel extracellular matrix.

Kristofik NJ, Qin L, Calabro NE, Dimitrievska S, Li G, Tellides G, Niklason LE, Kyriakides TR.

Biomaterials. 2017 Oct;141:63-73. doi: 10.1016/j.biomaterials.2017.06.025. Epub 2017 Jun 22.


The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis.

Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, Song L, Zhou X, Chen J, Zhou H, Zhang H, Tellides G, Min W, Yu L.

Nat Commun. 2017 Jun 1;8:15426. doi: 10.1038/ncomms15426.


Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms.

Bellini C, Bersi MR, Caulk AW, Ferruzzi J, Milewicz DM, Ramirez F, Rifkin DB, Tellides G, Yanagisawa H, Humphrey JD.

J R Soc Interface. 2017 May;14(130). pii: 20161036. doi: 10.1098/rsif.2016.1036.


Deficient Circumferential Growth Is the Primary Determinant of Aortic Obstruction Attributable to Partial Elastin Deficiency.

Jiao Y, Li G, Korneva A, Caulk AW, Qin L, Bersi MR, Li Q, Li W, Mecham RP, Humphrey JD, Tellides G.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):930-941. doi: 10.1161/ATVBAHA.117.309079. Epub 2017 Mar 2.


Biomechanical Phenotyping of the Murine Aorta: What Is the Best Control?

Bellini C, Caulk AW, Li G, Tellides G, Humphrey JD.

J Biomech Eng. 2017 Apr 1;139(4). doi: 10.1115/1.4035551.


Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.

Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):328-340. doi: 10.1161/ATVBAHA.116.308507. Epub 2016 Nov 10.


Loss of Elastic Fiber Integrity Compromises Common Carotid Artery Function: Implications for Vascular Aging.

Ferruzzi J, Bersi MR, Mecham RP, Ramirez F, Yanagisawa H, Tellides G, Humphrey JD.

Artery Res. 2016 Jun;14:41-52. Epub 2016 Apr 22.


Hemodynamics-driven deposition of intraluminal thrombus in abdominal aortic aneurysms.

Di Achille P, Tellides G, Humphrey JD.

Int J Numer Method Biomed Eng. 2017 May;33(5). doi: 10.1002/cnm.2828. Epub 2016 Oct 7.


Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice.

Kristofik N, Calabro NE, Tian W, Meng A, MacLauchlan S, Wang Y, Breuer CK, Tellides G, Niklason LE, Kyriakides TR.

Blood. 2016 Sep 22;128(12):1642-50. doi: 10.1182/blood-2016-03-702845. Epub 2016 Jul 28.


Implantable tissue-engineered blood vessels from human induced pluripotent stem cells.

Gui L, Dash BC, Luo J, Qin L, Zhao L, Yamamoto K, Hashimoto T, Wu H, Dardik A, Tellides G, Niklason LE, Qyang Y.

Biomaterials. 2016 Sep;102:120-9. doi: 10.1016/j.biomaterials.2016.06.010. Epub 2016 Jun 14.


Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression.

Chen PY, Qin L, Li G, Tellides G, Simons M.

EMBO Mol Med. 2016 Jul 1;8(7):712-28. doi: 10.15252/emmm.201506181. Print 2016 Jul.


Complement C5 Inhibition Reduces T Cell-Mediated Allograft Vasculopathy Caused by Both Alloantibody and Ischemia Reperfusion Injury in Humanized Mice.

Qin L, Li G, Kirkiles-Smith N, Clark P, Fang C, Wang Y, Yu ZX, Devore D, Tellides G, Pober JS, Jane-Wit D.

Am J Transplant. 2016 Oct;16(10):2865-2876. doi: 10.1111/ajt.13834. Epub 2016 Jun 14.


Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties.

Ferruzzi J, Murtada SI, Li G, Jiao Y, Uman S, Ting MY, Tellides G, Humphrey JD.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):919-27. doi: 10.1161/ATVBAHA.116.307436. Epub 2016 Mar 17.

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