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Items: 16

1.

The Relative Role of CYP3A4 and CYP3A5 in Eplerenone Metabolism.

McGraw J, Cherney M, Bichler K, Gerhardt A, Nauman M.

Toxicol Lett. 2019 Aug 10. pii: S0378-4274(19)30218-8. doi: 10.1016/j.toxlet.2019.08.003. [Epub ahead of print]

PMID:
31408697
2.

Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans.

Do AN, Zhao W, Baldridge AS, Raffield LM, Wiggins KL, Shah SJ, Aslibekyan S, Tiwari HK, Limdi N, Zhi D, Sitlani CM, Taylor KD, Psaty BM, Sotoodehnia N, Brody JA, Rasmussen-Torvik LJ, Lloyd-Jones D, Lange LA, Wilson JG, Smith JA, Kardia SLR, Mosley TH, Vasan RS, Arnett DK, Irvin MR.

Mol Genet Genomic Med. 2019 Aug 13:e788. doi: 10.1002/mgg3.788. [Epub ahead of print]

3.

Human H1 receptor (HRH1) gene polymorphism is associated with the severity of side effects after desloratadine treatment in Chinese patients with chronic spontaneous uticaria.

Li J, Chen W, Peng C, Zhu W, Liu Z, Zhang W, Su J, Li J, Chen X.

Pharmacogenomics J. 2019 Aug 13. doi: 10.1038/s41397-019-0094-0. [Epub ahead of print]

PMID:
31406237
4.

Impact of frailty, melphalan pharmacokinetics, and pharmacogenetics on outcomes post autologous hematopoietic cell transplantation for multiple myeloma.

Nampoothiri RV, Kasudhan KS, Patil AN, Malhotra P, Khadwal A, Prakash G, Jain A, Malhotra S, Verma Attri S, Varma N, Varma S, Lad DP.

Bone Marrow Transplant. 2019 Aug 12. doi: 10.1038/s41409-019-0631-0. [Epub ahead of print]

PMID:
31406224
5.

The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids.

Prill S, Caddeo A, Baselli G, Jamialahmadi O, Dongiovanni P, Rametta R, Kanebratt KP, Pujia A, Pingitore P, Mancina RM, Lindén D, Whatling C, Janefeldt A, Kozyra M, Ingelman-Sundberg M, Valenti L, Andersson TB, Romeo S.

Sci Rep. 2019 Aug 12;9(1):11585. doi: 10.1038/s41598-019-47737-w.

6.

KRAS-Driven Lung Adenocarcinoma and B Cell Infiltration: Novel Insights for Immunotherapy.

Pinto R, Petriella D, Lacalamita R, Montrone M, Catino A, Pizzutilo P, Botticella MA, Zito FA, Del Bene G, Zonno A, Tommasi S, De Summa S.

Cancers (Basel). 2019 Aug 9;11(8). pii: E1145. doi: 10.3390/cancers11081145.

7.

Neurodegeneration with brain iron accumulation: Insights into the mitochondria dysregulation.

Wang ZB, Liu JY, Xu XJ, Mao XY, Zhang W, Zhou HH, Liu ZQ.

Biomed Pharmacother. 2019 Aug 9;118:109068. doi: 10.1016/j.biopha.2019.109068. [Epub ahead of print] Review.

8.

Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts.

Iwaki H, Blauwendraat C, Leonard HL, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA.

Neurol Genet. 2019 Jul 9;5(4):e348. doi: 10.1212/NXG.0000000000000348. eCollection 2019 Aug.

9.

Genetic literacy series: clinical application of pharmacogenetics for adverse reactions to antiepileptic drugs.

Zhang Z, Wu Y, Tan NC, Jiang Y.

Epileptic Disord. 2019 Aug 1;21(4):330-336. doi: 10.1684/epd.2019.1087.

PMID:
31403464
10.

Neonatal Outcomes in Maternal Depression in Relation to Intrauterine Drug Exposure.

Corti S, Pileri P, Mazzocco MI, Mandò C, Moscatiello AF, Cattaneo D, Cheli S, Baldelli S, Pogliani L, Clementi E, Cetin I.

Front Pediatr. 2019 Jul 26;7:309. doi: 10.3389/fped.2019.00309. eCollection 2019.

11.

An update on emerging drugs in osteosarcoma: towards tailored therapies?

Hattinger CM, Patrizio MP, Magagnoli F, Luppi S, Serra M.

Expert Opin Emerg Drugs. 2019 Aug 14:1-19. doi: 10.1080/14728214.2019.1654455. [Epub ahead of print]

PMID:
31401903
12.

Are Global Health Systems Ready for Transformative Therapies?

Faulkner E, Spinner DS, Ringo M, Carroll M.

Value Health. 2019 Jun;22(6):627-641. doi: 10.1016/j.jval.2019.04.1911.

PMID:
31198179
13.

Similarities and differences in the reproductive phenotypes of women with congenital hypogonadotrophic hypogonadism caused by GNRHR mutations and women with polycystic ovary syndrome.

Maione L, Fèvre A, Nettore IC, Manilall A, Francou B, Trabado S, Bouligand J, Guiochon-Mantel A, Delemer B, Flanagan CA, Macchia PE, Millar RP, Young J.

Hum Reprod. 2019 Jan 1;34(1):137-147. doi: 10.1093/humrep/dey339.

PMID:
30476149
14.

Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression.

Romero P, Benhamo V, Deniziaut G, Fuhrmann L, Berger F, Manié E, Bhalshankar J, Vacher S, Laurent C, Marangoni E, Gruel N, MacGrogan G, Rouzier R, Delattre O, Popova T, Reyal F, Stern MH, Stoppa-Lyonnet D, Marchiò C, Bièche I, Vincent-Salomon A.

Am J Pathol. 2018 Oct;188(10):2378-2391. doi: 10.1016/j.ajpath.2018.06.021. Epub 2018 Aug 1.

PMID:
30075151
15.

Role of genetics in the prediction of statin-associated muscle symptoms and optimization of statin use and adherence.

Brunham LR, Baker S, Mammen A, Mancini GBJ, Rosenson RS.

Cardiovasc Res. 2018 Jul 1;114(8):1073-1081. doi: 10.1093/cvr/cvy119.

16.

Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population.

Cai LL, Huang WQ, Su ZY, Ye HM, Wang LS, Wu Y, Zhang ZY, Zhang W, Tzeng CM.

Sci Rep. 2017 Dec 12;7(1):17379. doi: 10.1038/s41598-017-17731-1.

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