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Items: 7

1.

Using the drug-protein interactome to identify anti-ageing compounds for humans.

Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L.

PLoS Comput Biol. 2019 Jan 9;15(1):e1006639. doi: 10.1371/journal.pcbi.1006639. [Epub ahead of print]

2.

Repositioning Tacrolimus: Evaluation of the Effect of Short-Term Tacrolimus Treatment on Osteoprogenitor Cells and Primary Cells for Bone Regenerative Engineering.

O'Neill E, Rajpura K, Carbone EJ, Awale G, Kan HM, Lo KW.

Assay Drug Dev Technol. 2019 Jan 9. doi: 10.1089/adt.2018.876. [Epub ahead of print]

PMID:
30624955
3.

Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia.

Alfedi G, Luffarelli R, Condò I, Pedini G, Mannucci L, Massaro DS, Benini M, Toschi N, Alaimo G, Panarello L, Pacini L, Fortuni S, Serio D, Malisan F, Testi R, Rufini A.

Mov Disord. 2019 Jan 9. doi: 10.1002/mds.27604. [Epub ahead of print]

PMID:
30624801
4.

Breaking the paradigm: Dr. Insight empowers signature-free, enhanced drug repurposing.

Chan J, Wang X, Turner J, Baldwin N, Gu J.

Bioinformatics. 2019 Jan 8. doi: 10.1093/bioinformatics/btz006. [Epub ahead of print]

PMID:
30624606
5.

Association of Hydroxylmethyl Glutaryl Coenzyme A Reductase Inhibitors, L-Type Calcium Channel Antagonists, and Biguanides With Rates of Psychiatric Hospitalization and Self-Harm in Individuals With Serious Mental Illness.

Hayes JF, Lundin A, Wicks S, Lewis G, Wong ICK, Osborn DPJ, Dalman C.

JAMA Psychiatry. 2019 Jan 9. doi: 10.1001/jamapsychiatry.2018.3907. [Epub ahead of print]

PMID:
30624557
6.

Tetramethylpyrazine Improves Postoperative Tissue Adhesion: A Drug Repurposing.

Yan S, Yue YZ, Zong Y, Zeng L.

Chin J Integr Med. 2019 Jan 9. doi: 10.1007/s11655-018-3021-3. [Epub ahead of print] Review.

PMID:
30623344
7.

Identifying Protein Features Responsible for Improved Drug Repurposing Accuracies Using the CANDO Platform: Implications for Drug Design.

Mangione W, Samudrala R.

Molecules. 2019 Jan 4;24(1). pii: E167. doi: 10.3390/molecules24010167.

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