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Items: 1 to 20 of 617

1.

Characterization of host responses during Pseudomonas aeruginosa acute lung infection in the lungs and blood and after treatment with the synthetic immunomodulatory peptide IDR-1002.

Wuerth K, Lee AHY, Falsafi R, Gill EE, Hancock REW.

Infect Immun. 2018 Oct 15. pii: IAI.00661-18. doi: 10.1128/IAI.00661-18. [Epub ahead of print]

2.

Antimicrobial Effect of Peptide DJK-5 Used Alone or Mixed with EDTA on Mono- and Multispecies Biofilms in Dentin Canals.

Wang D, Shen Y, Hancock REW, Ma J, Haapasalo M.

J Endod. 2018 Sep 19. pii: S0099-2399(18)30514-4. doi: 10.1016/j.joen.2018.07.018. [Epub ahead of print]

PMID:
30243660
3.

Surfing Motility: A Conserved yet Diverse Adaptation among Motile Bacteria.

Sun E, Liu S, Hancock REW.

J Bacteriol. 2018 Sep 17. pii: JB.00394-18. doi: 10.1128/JB.00394-18. [Epub ahead of print]

PMID:
30224438
4.

Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells.

Forbester JL, Lees EA, Goulding D, Forrest S, Yeung A, Speak A, Clare S, Coomber EL, Mukhopadhyay S, Kraiczy J, Schreiber F, Lawley TD, Hancock REW, Uhlig HH, Zilbauer M, Powrie F, Dougan G.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10118-10123. doi: 10.1073/pnas.1811866115. Epub 2018 Sep 14.

5.

Design and Assessment of Anti-Biofilm Peptides: Steps Toward Clinical Application.

Dostert M, Belanger CR, Hancock REW.

J Innate Immun. 2018 Aug 22:1-12. doi: 10.1159/000491497. [Epub ahead of print] Review.

6.

Broad-Spectrum Adaptive Antibiotic Resistance Associated with Pseudomonas aeruginosa Mucin-Dependent Surfing Motility.

Sun E, Gill EE, Falsafi R, Yeung A, Liu S, Hancock REW.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00848-18. doi: 10.1128/AAC.00848-18. Print 2018 Sep.

PMID:
29967020
7.

Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin.

Wolfmeier H, Mansour SC, Liu LT, Pletzer D, Draeger A, Babiychuk EB, Hancock REW.

EBioMedicine. 2018 Jul;33:211-217. doi: 10.1016/j.ebiom.2018.06.016. Epub 2018 Jun 20.

8.

Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens.

Pletzer D, Mansour SC, Hancock REW.

PLoS Pathog. 2018 Jun 21;14(6):e1007084. doi: 10.1371/journal.ppat.1007084. eCollection 2018 Jun.

9.

Critical Assessment of Methods to Quantify Biofilm Growth and Evaluate Antibiofilm Activity of Host Defence Peptides.

Haney EF, Trimble MJ, Cheng JT, Vallé Q, Hancock REW.

Biomolecules. 2018 May 21;8(2). pii: E29. doi: 10.3390/biom8020029.

10.

Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines.

Mwanza-Lisulo M, Chomba MS, Chama M, Besa EC, Funjika E, Zyambo K, Banda R, Imikendu M, Sianongo S, Hancock REW, Lee A, Chilengi R, Stagg AJ, Namangala B, Kelly PM.

Vaccine. 2018 Jun 27;36(28):4134-4141. doi: 10.1016/j.vaccine.2018.04.083. Epub 2018 May 22.

11.

Development of Molecularly Imprinted Polymers To Block Quorum Sensing and Inhibit Bacterial Biofilm Formation.

Ma L, Feng S, Fuente-Núñez C, Hancock REW, Lu X.

ACS Appl Mater Interfaces. 2018 Jun 6;10(22):18450-18457. doi: 10.1021/acsami.8b01584. Epub 2018 May 25.

PMID:
29767954
12.

Helicobacter pylori Biofilm Formation Is Differentially Affected by Common Culture Conditions, and Proteins Play a Central Role in the Biofilm Matrix.

Windham IH, Servetas SL, Whitmire JM, Pletzer D, Hancock REW, Merrell DS.

Appl Environ Microbiol. 2018 Jul 2;84(14). pii: e00391-18. doi: 10.1128/AEM.00391-18. Print 2018 Jul 15.

PMID:
29752266
13.

In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design.

Porto WF, Irazazabal L, Alves ESF, Ribeiro SM, Matos CO, Pires ÁS, Fensterseifer ICM, Miranda VJ, Haney EF, Humblot V, Torres MDT, Hancock REW, Liao LM, Ladram A, Lu TK, de la Fuente-Nunez C, Franco OL.

Nat Commun. 2018 Apr 16;9(1):1490. doi: 10.1038/s41467-018-03746-3.

14.

High-throughput detection of RNA processing in bacteria.

Gill EE, Chan LS, Winsor GL, Dobson N, Lo R, Ho Sui SJ, Dhillon BK, Taylor PK, Shrestha R, Spencer C, Hancock REW, Unrau PJ, Brinkman FSL.

BMC Genomics. 2018 Mar 27;19(1):223. doi: 10.1186/s12864-018-4538-8.

15.

Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms.

Haney EF, Brito-Sánchez Y, Trimble MJ, Mansour SC, Cherkasov A, Hancock REW.

Sci Rep. 2018 Jan 30;8(1):1871. doi: 10.1038/s41598-018-19669-4.

16.

Induction by innate defence regulator peptide 1018 of pro-angiogenic molecules and endothelial cell migration in a high glucose environment.

Marin-Luevano P, Trujillo V, Rodriguez-Carlos A, González-Curiel I, Enciso-Moreno JA, Hancock REW, Rivas-Santiago B.

Peptides. 2018 Mar;101:135-144. doi: 10.1016/j.peptides.2018.01.010. Epub 2018 Jan 17.

PMID:
29353019
17.

New Perspectives in Biofilm Eradication.

Wolfmeier H, Pletzer D, Mansour SC, Hancock REW.

ACS Infect Dis. 2018 Feb 9;4(2):93-106. doi: 10.1021/acsinfecdis.7b00170. Epub 2017 Dec 27.

PMID:
29280609
18.

Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection.

Wuerth KC, Falsafi R, Hancock REW.

PLoS One. 2017 Nov 6;12(11):e0187565. doi: 10.1371/journal.pone.0187565. eCollection 2017.

19.

Synthetic Peptides to Target Stringent Response-Controlled Virulence in a Pseudomonas aeruginosa Murine Cutaneous Infection Model.

Pletzer D, Wolfmeier H, Bains M, Hancock REW.

Front Microbiol. 2017 Sep 27;8:1867. doi: 10.3389/fmicb.2017.01867. eCollection 2017.

20.

Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model.

Wu BC, Lee AH, Hancock REW.

J Immunol. 2017 Nov 15;199(10):3592-3603. doi: 10.4049/jimmunol.1700985. Epub 2017 Oct 9.

PMID:
28993516

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