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Cancer Biol Med. 2017 Aug;14(3):228-241. doi: 10.20892/j.issn.2095-3941.2017.0052.

Recent progress on nanoparticle-based drug delivery systems for cancer therapy.

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College of Life Science and Technology, National Engineering Research Center for Nanomedicine, Huazhong University of Science and Technology, Wuhan 430074, China.


The development of cancer nanotherapeutics has attracted great interest in the recent decade. Cancer nanotherapeutics have overcome several limitations of conventional therapies, such as nonspecific biodistribution, poor water solubility, and limited bioavailability. Nanoparticles with tuned size and surface characteristics are the key components of nanotherapeutics, and are designed to passively or actively deliver anti-cancer drugs to tumor cells. We provide an overview of nanoparticle-based drug delivery methods and cancer therapies based on tumor-targeting delivery strategies that have been developed in recent years.


Nanoparticles; cancer therapy; drug delivery; nanomedicine; tumor targeting

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