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Int J Biol Macromol. 2018 Aug;115:1218-1224. doi: 10.1016/j.ijbiomac.2018.04.129. Epub 2018 Apr 25.

Electrospun plant mucilage nanofibers as biocompatible scaffolds for cell proliferation.

Author information

1
Department of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
2
Department of Animal Science, University of Wisconsin-Madison, Madison, WI 53706, USA.
3
Department of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: guna@wisc.edu.

Abstract

Electrospun nanofibers (ESNFs) were prepared from mucilage isolated from chan and linaza beans and mozote stem commercially available in Costa Rica. Poly(vinyl alcohol) (PVA) was used as an aiding agent. Mucilage/PVA mixed solutions of different volume ratios (100:0, 80:20, 60:40, 40:60, 20:80 and 0:100) were prepared and adjusted to be similar in viscosity and electrical conductivity suitable for electrospinning. Morphology of the ESNFs was examined using scanning electron microscopy (SEM). Fourier transform infrared spectrometer (FTIR) and differential scanning calorimetry (DSC) studies were used to characterize chemical composition and thermal characteristics of the nanofibers (NFs). The ability of the NFs to support fibroblast cell proliferation was investigated in vitro using the optimized mucilage/PVA solutions. Results show plant mucilage-based ESNFs are well-suited for fibroblast cell growth, significantly better than ESNFs of PVA; and the mucilage of chan beans is better than those of mozote and linaza for supporting cell proliferation.

KEYWORDS:

Electrospinning; Mucilage; Nanofibers; Poly(vinyl alcohol); Tissue engineering

PMID:
29702172
DOI:
10.1016/j.ijbiomac.2018.04.129
[Indexed for MEDLINE]

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