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1.
J Photochem Photobiol B. 2019 Jun;195:67. doi: 10.1016/j.jphotobiol.2019.01.020. Epub 2019 Feb 8.

Corrigendum to "Anticancer, antimicrobial and photocatalytic activities of green synthesized magnesium oxide nanoparticles (MgONPs) using aqueous extract of Sargassum wightii" [Journal of Photochemistry and Photobiology B: Biology 190, January 2019, Pages 86-97].

Author information

1
Innovative Green Product Synthesis and Renewable Environment Development Research Group, Faculty of Environment and Labour Safety, Ton Duc Thang University, Ho Chi Minh City, Viet Nam.
2
Department of Nanoscience and Technology, Alagappa University, Karaikudi, Tamil Nadu, India.
3
Institute of Research and Development, Duy Tan University, Da Nang 550000, Viet Nam.
4
Department of Nanoscience and Technology, Alagappa University, Karaikudi, Tamil Nadu, India. Electronic address: suganthyn@alagappauniversity.ac.in.
2.
J Photochem Photobiol B. 2019 Jan;190:86-97. doi: 10.1016/j.jphotobiol.2018.11.014. Epub 2018 Nov 23.

Anticancer, antimicrobial and photocatalytic activities of green synthesized magnesium oxide nanoparticles (MgONPs) using aqueous extract of Sargassum wightii.

Author information

1
Innovative Green Product Synthesis and Renewable Environment Development Research Group, Faculty of Environment and Labour Safety, Ton Duc Thang University, Ho Chi Minh City, Viet Nam.
2
Department of Nanoscience and Technology, Alagappa University, Karaikudi, Tamil Nadu, India.
3
Institute of Research and Development, Duy Tan University, Da Nang 550000, Viet Nam.
4
Department of Nanoscience and Technology, Alagappa University, Karaikudi, Tamil Nadu, India. Electronic address: suganthyn@alagappauniversity.ac.in.

Abstract

A rapid and ecofriendly fabrication of metal oxide nanoparticles using biogenic sources is the current trend being used to replace the toxic chemical method. The present study was carried out to synthesize magnesium oxide nanoparticles (MgONPs) using the marine brown algae Sargassum wighitii as the reducing and capping agent. The as-prepared MgONPs were characterized by spectroscopic and microscopic analyses. UV-visible spectrum of the MgONPs showed a sharp absorption peak at 322 nm. X- ray diffraction analysis illustrated that the MgONPs were crystalline in nature with a face-centered cubic structure. Presence of magnesium and oxygen were further confirmed by EDX profile. FTIR analysis showed the presence of functional groups specific for sulfated polysaccharides, which might be responsible for the synthesis of MgONPs. Zeta potential and dynamic light scattering analysis illustrated that the MgONPs were highly stable at 19.8 mV with an average size of 68.06 nm. MgONPs showed potent antibacterial activity and antifungal activities against human pathogens. Photocatalytic activity of MgONPs was witnessed by the quick degradation of the organic dye methylene blue on exposure to both sunlight and UV irradiation. MgONPs showed significant cytotoxicity against the lung cancer cell lines A549 in a dose dependent manner with the IC50 value of 37.5 ± 0.34 μg/ml. Safety evaluation using peripheral blood mononuclear cells (PBMCs) illustrated the MgONPs to be non-toxic in nature. Overall, the results concluded that the MgONPs generated using marine algae have exhibited scope for multifaceted biological applications.

KEYWORDS:

A549 cell lines; Antimicrobial activity; Cytotoxicity; MgONPs; Photocatalytic activity; Sargassum wightii

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