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Clin Pharmacol Ther. 2016 Nov;100(5):398-403. doi: 10.1002/cpt.454.

Drug Transporters: Advances and Opportunities.

Author information

1
Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
2
Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA. sparreboom.1@osu.edu.

Abstract

Drug transporter research conducted over the last several decades has led to a greatly advanced understanding of the mechanisms underlying the principles of drug absorption and disposition. Although many transporters remain poorly characterized, there is ample evidence that the drug transporter field will ultimately provide vital support to routine patient management, and will play a key role in the discovery, development, and evaluation of innovative, cutting-edge therapies.

PMID:
27718234
DOI:
10.1002/cpt.454
[Indexed for MEDLINE]

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