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Items: 1 to 20 of 98


The structure of the actin-smooth muscle myosin motor domain complex in the rigor state.

Banerjee C, Hu Z, Huang Z, Warrington JA, Taylor DW, Trybus KM, Lowey S, Taylor KA.

J Struct Biol. 2017 Dec;200(3):325-333. doi: 10.1016/j.jsb.2017.10.003. Epub 2017 Oct 14.


Fission yeast myosin Myo2 is down-regulated in actin affinity by light chain phosphorylation.

Pollard LW, Bookwalter CS, Tang Q, Krementsova EB, Trybus KM, Lowey S.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7236-E7244. doi: 10.1073/pnas.1703161114. Epub 2017 Aug 14.


Opening the door to your nursing potential.

Lowey S.

Nurs Manag (Harrow). 2017 Mar 30;24(1):14. doi: 10.7748/nm.24.1.14.s20.


Role of the essential light chain in the activation of smooth muscle myosin by regulatory light chain phosphorylation.

Taylor KA, Feig M, Brooks CL 3rd, Fagnant PM, Lowey S, Trybus KM.

J Struct Biol. 2014 Mar;185(3):375-82. doi: 10.1016/j.jsb.2013.12.008. Epub 2013 Dec 19.


Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.

Lowey S, Bretton V, Gulick J, Robbins J, Trybus KM.

J Biol Chem. 2013 May 24;288(21):14780-7. doi: 10.1074/jbc.M113.450668. Epub 2013 Apr 11.


Common structural motifs for the regulation of divergent class II myosins.

Lowey S, Trybus KM.

J Biol Chem. 2010 May 28;285(22):16403-7. doi: 10.1074/jbc.R109.025551. Epub 2010 Mar 25. Review.


Crystal structures of monomeric actin bound to cytochalasin D.

Nair UB, Joel PB, Wan Q, Lowey S, Rould MA, Trybus KM.

J Mol Biol. 2008 Dec 26;384(4):848-64. doi: 10.1016/j.jmb.2008.09.082. Epub 2008 Oct 10.


Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.

Lowey S, Lesko LM, Rovner AS, Hodges AR, White SL, Low RB, Rincon M, Gulick J, Robbins J.

J Biol Chem. 2008 Jul 18;283(29):20579-89. doi: 10.1074/jbc.M800554200. Epub 2008 May 13.


The R403Q myosin mutation implicated in familial hypertrophic cardiomyopathy causes disorder at the actomyosin interface.

Volkmann N, Lui H, Hazelwood L, Trybus KM, Lowey S, Hanein D.

PLoS One. 2007 Nov 7;2(11):e1123.


Evidence for an interaction between the SH3 domain and the N-terminal extension of the essential light chain in class II myosins.

Lowey S, Saraswat LD, Liu H, Volkmann N, Hanein D.

J Mol Biol. 2007 Aug 24;371(4):902-13. Epub 2007 Jun 2.


Crystal structures of expressed non-polymerizable monomeric actin in the ADP and ATP states.

Rould MA, Wan Q, Joel PB, Lowey S, Trybus KM.

J Biol Chem. 2006 Oct 20;281(42):31909-19. Epub 2006 Aug 18.


The structural basis of myosin V processive movement as revealed by electron cryomicroscopy.

Volkmann N, Liu H, Hazelwood L, Krementsova EB, Lowey S, Trybus KM, Hanein D.

Mol Cell. 2005 Sep 2;19(5):595-605.


Cardiac myosin isoforms from different species have unique enzymatic and mechanical properties.

Malmqvist UP, Aronshtam A, Lowey S.

Biochemistry. 2004 Nov 30;43(47):15058-65.


A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin.

Sherwood JJ, Waller GS, Warshaw DM, Lowey S.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10973-8. Epub 2004 Jul 15.


So near and yet so far from understanding molecular motors: recollections in honor of John T. Edsall.

Lowey S.

Biophys Chem. 2003;100(1-3):171-5. No abstract available.


Myosin isoforms show unique conformations in the actin-bound state.

Volkmann N, Ouyang G, Trybus KM, DeRosier DJ, Lowey S, Hanein D.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3227-32. Epub 2003 Feb 28.


The carboxyl-terminal isoforms of smooth muscle myosin heavy chain determine thick filament assembly properties.

Rovner AS, Fagnant PM, Lowey S, Trybus KM.

J Cell Biol. 2002 Jan 7;156(1):113-23. Epub 2002 Jan 7.


The power stroke causes changes in the orientation and mobility of the termini of essential light chain 1 of myosin.

Borejdo J, Ushakov DS, Moreland R, Akopova I, Reshetnyak Y, Saraswat LD, Kamm K, Lowey S.

Biochemistry. 2001 Apr 3;40(13):3796-803.


Evidence for cleft closure in actomyosin upon ADP release.

Volkmann N, Hanein D, Ouyang G, Trybus KM, DeRosier DJ, Lowey S.

Nat Struct Biol. 2000 Dec;7(12):1147-55.


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