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Immunopharmacol Immunotoxicol. 2011 Mar;33(1):107-10. doi: 10.3109/08923973.2010.484839. Epub 2010 May 12.

Immunotoxicity activity of the major essential oils of Valeriana fauriei Briq against Aedes aegypti L.

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1
Department of Applied Life science, Kon Kuk University, Seoul, South Korea.

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Abstract

The rhizomes and roots of Valeriana fauriei were extracted and the major essential oil composition and immunotoxicity effects were studied. The analyses were conducted by gas chromatography-mass spectroscopy (GC-MS) revealed that the essential oils of V. fauriei. The V. fauriei essential oil (VFEO) yield was 1.93%, and GC/MS analysis revealed that its major constituents were bornyl acetate (32.83%), terpinyl acetate (3.82%), bornyl isovalerate (2.11%), β-sesquiphellandrene (2.21%), sesquiterpene alcohol (7.32%), and cedrol (2.45%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC(50) value of 30.44 ppm and an LC(90) value of 82.64 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxicity agents against Aedes aegypti L.

PMID:
20462349
DOI:
10.3109/08923973.2010.484839
[Indexed for MEDLINE]

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