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Items: 1 to 20 of 103

1.

Targeting DNAJB9, a novel ER luminal co-chaperone, to rescue ΔF508-CFTR.

Huang Y, Arora K, Mun KS, Yang F, Moon C, Yarlagadda S, Jegga A, Weaver T, Naren AP.

Sci Rep. 2019 Jul 8;9(1):9808. doi: 10.1038/s41598-019-46161-4.

2.

Genetic Influences on Behavioral Outcomes After Childhood TBI: A Novel Systems Biology-Informed Approach.

Kurowski BG, Treble-Barna A, Pilipenko V, Wade SL, Yeates KO, Taylor HG, Martin LJ, Jegga AG.

Front Genet. 2019 May 22;10:481. doi: 10.3389/fgene.2019.00481. eCollection 2019.

3.

Dysregulation of Mesenchymal Cell Survival Pathways in Severe Fibrotic Lung Disease: The Effect of Nintedanib Therapy.

Kasam RK, Reddy GB, Jegga AG, Madala SK.

Front Pharmacol. 2019 May 17;10:532. doi: 10.3389/fphar.2019.00532. eCollection 2019.

4.

Transcriptomic Data Mining and Repurposing for Computational Drug Discovery.

Wang Y, Yella J, Jegga AG.

Methods Mol Biol. 2019;1903:73-95. doi: 10.1007/978-1-4939-8955-3_5.

PMID:
30547437
5.

Wilms' tumor 1 drives fibroproliferation and myofibroblast transformation in severe fibrotic lung disease.

Sontake V, Kasam RK, Sinner D, Korfhagen TR, Reddy GB, White ES, Jegga AG, Madala SK.

JCI Insight. 2018 Aug 23;3(16). pii: 121252. doi: 10.1172/jci.insight.121252. eCollection 2018 Aug 23.

6.

Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1.

Hankey W, Chen Z, Bergman MJ, Fernandez MO, Hancioglu B, Lan X, Jegga AG, Zhang J, Jin VX, Aronow BJ, Wang Q, Groden J.

Oncotarget. 2018 Jul 27;9(58):31214-31230. doi: 10.18632/oncotarget.25781. eCollection 2018 Jul 27.

7.

An Hsp20-FBXO4 Axis Regulates Adipocyte Function through Modulating PPARγ Ubiquitination.

Peng J, Li Y, Wang X, Deng S, Holland J, Yates E, Chen J, Gu H, Essandoh K, Mu X, Wang B, McNamara RK, Peng T, Jegga AG, Liu T, Nakamura T, Huang K, Perez-Tilve D, Fan GC.

Cell Rep. 2018 Jun 19;23(12):3607-3620. doi: 10.1016/j.celrep.2018.05.065.

8.

Novel phenotype-disease matching tool for rare genetic diseases.

Chen J, Xu H, Jegga A, Zhang K, White PS, Zhang G.

Genet Med. 2019 Feb;21(2):339-346. doi: 10.1038/s41436-018-0050-4. Epub 2018 Jun 12.

PMID:
29895857
9.

GNOMICS: A one-stop shop for biomedical and genomic data.

Kronk CJ, Jegga A.

AMIA Jt Summits Transl Sci Proc. 2018 May 18;2017:118-123. eCollection 2018.

10.
11.

Changing Trends in Computational Drug Repositioning.

Yella JK, Yaddanapudi S, Wang Y, Jegga AG.

Pharmaceuticals (Basel). 2018 Jun 5;11(2). pii: E57. doi: 10.3390/ph11020057. Review.

12.

The nuclear DEK interactome supports multi-functionality.

Smith EA, Krumpelbeck EF, Jegga AG, Prell M, Matrka MM, Kappes F, Greis KD, Ali AM, Meetei AR, Wells SI.

Proteins. 2018 Jan;86(1):88-97. doi: 10.1002/prot.25411. Epub 2017 Nov 11.

13.

Unsupervised gene expression analyses identify IPF-severity correlated signatures, associated genes and biomarkers.

Wang Y, Yella J, Chen J, McCormack FX, Madala SK, Jegga AG.

BMC Pulm Med. 2017 Oct 20;17(1):133. doi: 10.1186/s12890-017-0472-9.

14.

Gene-disease associations identify a connectome with shared molecular pathways in human cholangiopathies.

Luo Z, Jegga AG, Bezerra JA.

Hepatology. 2018 Feb;67(2):676-689. doi: 10.1002/hep.29504. Epub 2018 Jan 2.

15.

Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.

Angel PM, Narmoneva DA, Sewell-Loftin MK, Munjal C, Dupuis L, Landis BJ, Jegga A, Kern CB, Merryman WD, Baldwin HS, Bressan GM, Hinton RB.

Ann Biomed Eng. 2017 Nov;45(11):2548-2562. doi: 10.1007/s10439-017-1899-0. Epub 2017 Aug 15.

16.

Generating testable hypotheses for schizophrenia and rheumatoid arthritis pathogenesis by integrating epidemiological, genomic, and protein interaction data.

Malavia TA, Chaparala S, Wood J, Chowdari K, Prasad KM, McClain L, Jegga AG, Ganapathiraju MK, Nimgaonkar VL.

NPJ Schizophr. 2017 Feb 24;3:11. doi: 10.1038/s41537-017-0010-z. eCollection 2017.

17.

Exome Sequencing Identifies Candidate Genetic Modifiers of Syndromic and Familial Thoracic Aortic Aneurysm Severity.

Landis BJ, Schubert JA, Lai D, Jegga AG, Shikany AR, Foroud T, Ware SM, Hinton RB.

J Cardiovasc Transl Res. 2017 Aug;10(4):423-432. doi: 10.1007/s12265-017-9753-1. Epub 2017 May 26.

18.

DEK is required for homologous recombination repair of DNA breaks.

Smith EA, Gole B, Willis NA, Soria R, Starnes LM, Krumpelbeck EF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Vinnedge LM, Daniel JA, Scully R, Wiesmüller L, Wells SI.

Sci Rep. 2017 Mar 20;7:44662. doi: 10.1038/srep44662.

19.

Applying Systems Biology Methodology To Identify Genetic Factors Possibly Associated with Recovery after Traumatic Brain Injury.

Kurowski BG, Treble-Barna A, Pitzer AJ, Wade SL, Martin LJ, Chima RS, Jegga A.

J Neurotrauma. 2017 Jul 15;34(14):2280-2290. doi: 10.1089/neu.2016.4856. Epub 2017 May 3.

20.

Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model.

Munjal C, Jegga AG, Opoka AM, Stoilov I, Norris RA, Thomas CJ, Smith JM, Mecham RP, Bressan GM, Hinton RB.

Physiol Rep. 2017 Mar;5(5). pii: e13152. doi: 10.14814/phy2.13152.

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