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Items: 1 to 20 of 871

1.

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

Rueda OM, Sammut SJ, Seoane JA, Chin SF, Caswell-Jin JL, Callari M, Batra R, Pereira B, Bruna A, Ali HR, Provenzano E, Liu B, Parisien M, Gillett C, McKinney S, Green AR, Murphy L, Purushotham A, Ellis IO, Pharoah PD, Rueda C, Aparicio S, Caldas C, Curtis C.

Nature. 2019 Mar 13. doi: 10.1038/s41586-019-1007-8. [Epub ahead of print]

PMID:
30867590
2.

clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers.

Campbell KR, Steif A, Laks E, Zahn H, Lai D, McPherson A, Farahani H, Kabeer F, O'Flanagan C, Biele J, Brimhall J, Wang B, Walters P, Consortium I, Bouchard-Côté A, Aparicio S, Shah SP.

Genome Biol. 2019 Mar 12;20(1):54. doi: 10.1186/s13059-019-1645-z.

3.

A Standardized and Reproducible Proteomics Protocol for Bottom-Up Quantitative Analysis of Protein Samples Using SP3 and Mass Spectrometry.

Hughes CS, Sorensen PH, Morin GB.

Methods Mol Biol. 2019;1959:65-87. doi: 10.1007/978-1-4939-9164-8_5.

PMID:
30852816
4.

Development of patient "profiles" to tailor counseling for incidental genomic sequencing results.

Mighton C, Carlsson L, Clausen M, Casalino S, Shickh S, McCuaig L, Joshi E, Panchal S, Graham T, Aronson M, Piccinin C, Winter-Paquette L, Semotiuk K, Lorentz J, Mancuso T, Ott K, Silberman Y, Elser C, Eisen A, Kim RH, Lerner-Ellis J, Carroll JC, Glogowski E, Schrader K, Bombard Y; Incidental Genomics Study Team.

Eur J Hum Genet. 2019 Mar 8. doi: 10.1038/s41431-019-0352-2. [Epub ahead of print]

PMID:
30846854
5.

Non-invasive Use of Positron Emission Tomography to Monitor Diethyl maleate and Radiation-Induced Changes in System xC- Activity in Breast Cancer.

Čolović M, Yang H, Merkens H, Colpo N, Bénard F, Schaffer P.

Mol Imaging Biol. 2019 Mar 5. doi: 10.1007/s11307-019-01331-8. [Epub ahead of print]

PMID:
30838549
6.

Critical Questions in Ovarian Cancer Research and Treatment: Report of an American Association for Cancer Research Special Conference.

Bast RC Jr, Matulonis UA, Sood AK, Ahmed AA, Amobi AE, Balkwill FR, Wielgos-Bonvallet M, Bowtell DDL, Brenton JD, Brugge JS, Coleman RL, Draetta GF, Doberstein K, Drapkin RI, Eckert MA, Edwards RP, Elias KM, Ennis D, Futreal A, Gershenson DM, Greenberg RA, Huntsman DG, Ji JXY, Kohn EC, Iavarone C, Lengyel ER, Levine DA, Lord CJ, Lu Z, Mills GB, Modugno F, Nelson BH, Odunsi K, Pilsworth JA, Rottapel RK, Powell DJ Jr, Shen L, Shih LM, Spriggs DR, Walton J, Zhang K, Zhang R, Zou L.

Cancer. 2019 Mar 5. doi: 10.1002/cncr.32004. [Epub ahead of print]

PMID:
30835824
7.

Base excision repair deficiency signatures implicate germline and somatic MUTYH aberrations in pancreatic ductal adenocarcinoma and breast cancer oncogenesis.

Thibodeau ML, Zhao EY, Reisle C, Ch'ng C, Wong HL, Shen Y, Jones MR, Lim HJ, Young S, Cremin C, Zhang W, Holt R, Eirew P, Karasinska J, Kalloger S, Taylor G, Majounie E, Bonakdar M, Zong Z, Bleile D, Chiu R, Birol I, Gelmon K, Lohrisch C, Mungall KL, Mungall AJ, Moore R, Ma YP, Fok A, Yip S, Karsan A, Huntsman D, Schaeffer DF, Laskin J, Marra MA, Renouf DJ, Jones SJM, Schrader KA.

Cold Spring Harb Mol Case Stud. 2019 Mar 4. pii: mcs.a003681. doi: 10.1101/mcs.a003681. [Epub ahead of print]

8.

Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models.

Funnell T, Zhang AW, Grewal D, McKinney S, Bashashati A, Wang YK, Shah SP.

PLoS Comput Biol. 2019 Feb 22;15(2):e1006799. doi: 10.1371/journal.pcbi.1006799. eCollection 2019 Feb.

9.

Retraction Note: A homing system targets therapeutic T cells to brain cancer.

Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N.

Nature. 2019 Mar;567(7746):132. doi: 10.1038/s41586-019-0967-z.

PMID:
30787441
10.

Positron Emission Tomography Imaging of the Gastrin-Releasing Peptide Receptor with a Novel Bombesin Analogue.

Lau J, Rousseau E, Zhang Z, Uribe CF, Kuo HT, Zeisler J, Zhang C, Kwon D, Lin KS, Bénard F.

ACS Omega. 2019 Jan 31;4(1):1470-1478. doi: 10.1021/acsomega.8b03293. Epub 2019 Jan 16.

11.

Dhaka: Variational Autoencoder for Unmasking Tumor Heterogeneity from Single Cell Genomic Data.

Rashid S, Shah S, Bar-Joseph Z, Pandya R.

Bioinformatics. 2019 Feb 15. pii: btz095. doi: 10.1093/bioinformatics/btz095. [Epub ahead of print]

PMID:
30768159
12.

Translational control in brain pathologies: biological significance and therapeutic opportunities.

Delaidelli A, Jan A, Herms J, Sorensen PH.

Acta Neuropathol. 2019 Feb 9. doi: 10.1007/s00401-019-01971-8. [Epub ahead of print] Review.

PMID:
30739199
13.

One-step 18F-labeling and preclinical evaluation of prostate specific membrane antigen trifluoroborate probes for cancer imaging.

Kuo HT, Lepage M, Lin KS, Pan J, Zhang Z, Liu Z, Pryyma A, Zhang C, Merkens H, Roxin A, Perrin D, Benard F.

J Nucl Med. 2019 Feb 8. pii: jnumed.118.216598. doi: 10.2967/jnumed.118.216598. [Epub ahead of print]

PMID:
30737299
14.

Part 1: Introduction to Machine Learning in the Nuclear Medicine Context.

Uribe CF, Mathotaarachchi S, Gaudet VC, Smith KC, Rosa-Neto P, Benard F, Black SE, Zukotynski K.

J Nucl Med. 2019 Feb 7. pii: jnumed.118.223495. doi: 10.2967/jnumed.118.223495. [Epub ahead of print]

PMID:
30733322
15.

Somatic mutation detection and classification through probabilistic integration of clonal population information.

Dorri F, Jewell S, Bouchard-Côté A, Shah SP.

Commun Biol. 2019 Jan 31;2:44. doi: 10.1038/s42003-019-0291-z. eCollection 2019.

16.

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes.

Artomov M, Joseph V, Tiao G, Thomas T, Schrader K, Klein RJ, Kiezun A, Gupta N, Margolin L, Stratigos AJ, Kim I, Shannon K, Ellisen LW, Haber D, Getz G, Tsao H, Lipkin SM, Altshuler D, Offit K, Daly MJ.

Eur J Hum Genet. 2019 Feb 4. doi: 10.1038/s41431-019-0346-0. [Epub ahead of print]

PMID:
30718883
17.

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition.

Ennishi D, Takata K, Béguelin W, Duns G, Mottok A, Farinha P, Bashashati A, Saberi S, Boyle M, Meissner B, Ben-Neriah S, Woolcock BW, Telenius A, Lai D, Teater M, Kridel R, Savage KJ, Sehn LH, Morin RD, Marra MA, Shah SP, Connors JM, Gascoyne RD, Scott DW, Melnick AM, Steidl C.

Cancer Discov. 2019 Jan 31. doi: 10.1158/2159-8290.CD-18-1090. [Epub ahead of print]

PMID:
30705065
18.

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion.

Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, Sorensen PH, Maris JM, Khan J, Mackall CL.

J Natl Cancer Inst. 2019 Jan 30. doi: 10.1093/jnci/djy209. [Epub ahead of print]

PMID:
30698726
19.

Shared heritability and functional enrichment across six solid cancers.

Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV, Barkardottir RB, Barnes DR, Batra J, Beckmann MW, Benitez J, Benlloch S, Berchuck A, Berndt SI, Bickeböller H, Bien SA, Blomqvist C, Boccia S, Bogdanova NV, Bojesen SE, Bolla MK, Brauch H, Brenner H, Brenton JD, Brook MN, Brunet J, Brunnström H, Buchanan DD, Burwinkel B, Butzow R, Cadoni G, Caldés T, Caligo MA, Campbell I, Campbell PT, Cancel-Tassin G, Cannon-Albright L, Campa D, Caporaso N, Carvalho AL, Chan AT, Chang-Claude J, Chanock SJ, Chen C, Christiani DC, Claes KBM, Claessens F, Clements J, Collée JM, Correa MC, Couch FJ, Cox A, Cunningham JM, Cybulski C, Czene K, Daly MB, deFazio A, Devilee P, Diez O, Gago-Dominguez M, Donovan JL, Dörk T, Duell EJ, Dunning AM, Dwek M, Eccles DM, Edlund CK, Edwards DRV, Ellberg C, Evans DG, Fasching PA, Ferris RL, Liloglou T, Figueiredo JC, Fletcher O, Fortner RT, Fostira F, Franceschi S, Friedman E, Gallinger SJ, Ganz PA, Garber J, García-Sáenz JA, Gayther SA, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, Goode EL, Goodman MT, Goodman G, Grankvist K, Greene MH, Gronberg H, Gronwald J, Guénel P, Håkansson N, Hall P, Hamann U, Hamdy FC, Hamilton RJ, Hampe J, Haugen A, Heitz F, Herrero R, Hillemanns P, Hoffmeister M, Høgdall E, Hong YC, Hopper JL, Houlston R, Hulick PJ, Hunter DJ, Huntsman DG, Idos G, Imyanitov EN, Ingles SA, Isaacs C, Jakubowska A, James P, Jenkins MA, Johansson M, Johansson M, John EM, Joshi AD, Kaneva R, Karlan BY, Kelemen LE, Kühl T, Khaw KT, Khusnutdinova E, Kibel AS, Kiemeney LA, Kim J, Kjaer SK, Knight JA, Kogevinas M, Kote-Jarai Z, Koutros S, Kristensen VN, Kupryjanczyk J, Lacko M, Lam S, Lambrechts D, Landi MT, Lazarus P, Le ND, Lee E, Lejbkowicz F, Lenz HJ, Leslie G, Lessel D, Lester J, Levine DA, Li L, Li CI, Lindblom A, Lindor NM, Liu G, Loupakis F, Lubiński J, Maehle L, Maier C, Mannermaa A, Marchand LL, Margolin S, May T, McGuffog L, Meindl A, Middha P, Miller A, Milne RL, MacInnis RJ, Modugno F, Montagna M, Moreno V, Moysich KB, Mucci L, Muir K, Mulligan AM, Nathanson KL, Neal DE, Ness AR, Neuhausen SL, Nevanlinna H, Newcomb PA, Newcomb LF, Nielsen FC, Nikitina-Zake L, Nordestgaard BG, Nussbaum RL, Offit K, Olah E, Olama AAA, Olopade OI, Olshan AF, Olsson H, Osorio A, Pandha H, Park JY, Pashayan N, Parsons MT, Pejovic T, Penney KL, Peters WHM, Phelan CM, Phipps AI, Plaseska-Karanfilska D, Pring M, Prokofyeva D, Radice P, Stefansson K, Ramus SJ, Raskin L, Rennert G, Rennert HS, van Rensburg EJ, Riggan MJ, Risch HA, Risch A, Roobol MJ, Rosenstein BS, Rossing MA, De Ruyck K, Saloustros E, Sandler DP, Sawyer EJ, Schabath MB, Schleutker J, Schmidt MK, Setiawan VW, Shen H, Siegel EM, Sieh W, Singer CF, Slattery ML, Sorensen KD, Southey MC, Spurdle AB, Stanford JL, Stevens VL, Stintzing S, Stone J, Sundfeldt K, Sutphen R, Swerdlow AJ, Tajara EH, Tangen CM, Tardon A, Taylor JA, Teare MD, Teixeira MR, Terry MB, Terry KL, Thibodeau SN, Thomassen M, Bjørge L, Tischkowitz M, Toland AE, Torres D, Townsend PA, Travis RC, Tung N, Tworoger SS, Ulrich CM, Usmani N, Vachon CM, Van Nieuwenhuysen E, Vega A, Aguado-Barrera ME, Wang Q, Webb PM, Weinberg CR, Weinstein S, Weissler MC, Weitzel JN, West CML, White E, Whittemore AS, Wichmann HE, Wiklund F, Winqvist R, Wolk A, Woll P, Woods M, Wu AH, Wu X, Yannoukakos D, Zheng W, Zienolddiny S, Ziogas A, Zorn KK, Lane JM, Saxena R, Thomas D, Hung RJ, Diergaarde B, McKay J, Peters U, Hsu L, García-Closas M, Eeles RA, Chenevix-Trench G, Brennan PJ, Haiman CA, Simard J, Easton DF, Gruber SB, Pharoah PDP, Price AL, Pasaniuc B, Amos CI, Kraft P, Lindström S.

Nat Commun. 2019 Jan 25;10(1):431. doi: 10.1038/s41467-018-08054-4.

20.

18F-branched chain amino acids: structure-activity relationships and PET imaging potential.

Nodwell MB, Yang H, Merkens H, Malik N, Colovic M, Wagner B, Martin RE, Benard F, Schaffer P, Britton R.

J Nucl Med. 2019 Jan 25. pii: jnumed.118.220483. doi: 10.2967/jnumed.118.220483. [Epub ahead of print]

PMID:
30683769

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