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1.

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

Karlsson Linnér R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Zünd CL, Bao Y, Buzdugan L, Caplin AH, Chen CY, Eibich P, Fontanillas P, Gonzalez JR, Joshi PK, Karhunen V, Kleinman A, Levin RZ, Lill CM, Meddens GA, Muntané G, Sanchez-Roige S, Rooij FJV, Taskesen E, Wu Y, Zhang F; 23and Me Research Team; eQTLgen Consortium; International Cannabis Consortium; Social Science Genetic Association Consortium, Auton A, Boardman JD, Clark DW, Conlin A, Dolan CC, Fischbacher U, Groenen PJF, Harris KM, Hasler G, Hofman A, Ikram MA, Jain S, Karlsson R, Kessler RC, Kooyman M, MacKillop J, Männikkö M, Morcillo-Suarez C, McQueen MB, Schmidt KM, Smart MC, Sutter M, Thurik AR, Uitterlinden AG, White J, Wit H, Yang J, Bertram L, Boomsma DI, Esko T, Fehr E, Hinds DA, Johannesson M, Kumari M, Laibson D, Magnusson PKE, Meyer MN, Navarro A, Palmer AA, Pers TH, Posthuma D, Schunk D, Stein MB, Svento R, Tiemeier H, Timmers PRHJ, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger PD, Beauchamp JP.

Nat Genet. 2019 Jan 14. doi: 10.1038/s41588-018-0309-3. [Epub ahead of print]

PMID:
30643258
2.

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X; 23andMe Research Team; HUNT All-In Psychiatry, Choquet H, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunter DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Loukola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stančáková A, Stefansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold BS, Yin J, Zuccolo L, Bierut LJ, Hveem K, Lee JJ, Munafò MR, Saccone NL, Willer CJ, Cornelis MC, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Abecasis G, Liu DJ, Vrieze S.

Nat Genet. 2019 Jan 14. doi: 10.1038/s41588-018-0307-5. [Epub ahead of print]

PMID:
30643251
3.

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.

Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Adnan SD, Afaq S, Agrawal A, Altmaier E, Antoniou AC, Asselbergs FW, Baumbach C, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Eaton C, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hallmans G, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Hsu C, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Lai D, Langenberg C, Le N, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Müller-Nurasyid M, Naheed A, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Reiner A, Renström F, Rice J, Rohde R, Rolandsson O, Samani NJ, Samuel M, Schlessinger D, Scholte SH, Scott RA, Sever P, Shao Y, Shrine N, Smith JA, Starr JM, Stirrups K, Stram D, Stringham HM, Tachmazidou I, Tardif JC, Thompson DJ, Tindle HA, Tragante V, Trompet S, Turcot V, Tyrrell J, Vaartjes I, van der Leij AR, van der Meer P, Varga TV, Verweij N, Völzke H, Wareham NJ, Warren HR, Weir DR, Weiss S, Wetherill L, Yaghootkar H, Yavas E, Jiang Y, Chen F, Zhan X, Zhang W, Zhao W, Zhao W, Zhou K, Amouyel P, Blankenberg S, Caulfield MJ, Chowdhury R, Cucca F, Deary IJ, Deloukas P, Di Angelantonio E, Ferrario M, Ferrières J, Franks PW, Frayling TM, Frossard P, Hall IP, Hayward C, Jansson JH, Jukema JW, Kee F, Männistö S, Metspalu A, Munroe PB, Nordestgaard BG, Palmer CNA, Salomaa V, Sattar N, Spector T, Strachan DP; Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, van der Harst P, Zeggini E, Saleheen D, Butterworth AS, Wain LV, Abecasis GR, Danesh J, Tobin MD, Vrieze S, Liu DJ, Howson JMM.

Mol Psychiatry. 2019 Jan 7. doi: 10.1038/s41380-018-0313-0. [Epub ahead of print]

PMID:
30617275
4.

The Effect of Voluntary Wheel Running on 129/SvEvTac and C3H/Ibg Alcohol Consumption.

Booher WC, Hoft NR, Ehringer MA.

Alcohol. 2018 Oct 25. pii: S0741-8329(18)30184-8. doi: 10.1016/j.alcohol.2018.10.007. [Epub ahead of print]

PMID:
30616894
5.

The influence of stressful life events, psychopathy, and their interaction on internalizing and externalizing psychopathology.

Eisenbarth H, Godinez D, du Pont A, Corley RP, Stallings MC, Rhee SH.

Psychiatry Res. 2018 Dec 28;272:438-446. doi: 10.1016/j.psychres.2018.12.145. [Epub ahead of print]

PMID:
30611961
6.

Genetic and environmental relations of executive functions to antisocial personality disorder symptoms and psychopathy.

Friedman NP, Rhee SH, Ross JM, Corley RP, Hewitt JK.

Int J Psychophysiol. 2018 Dec 18. pii: S0167-8760(18)30331-3. doi: 10.1016/j.ijpsycho.2018.12.007. [Epub ahead of print]

PMID:
30576766
7.

The effects of oral nicotine administration and abstinence on sleep in male C57BL/6J mice.

Mathews HL, Stitzel JA.

Psychopharmacology (Berl). 2018 Dec 18. doi: 10.1007/s00213-018-5139-6. [Epub ahead of print]

PMID:
30564868
8.

Cryoprotectant toxicity in Caenorhabditis elegans.

Tedesco PM, Schumacher GJ, Johnson TE.

Cryobiology. 2018 Dec 4. pii: S0011-2240(18)30310-9. doi: 10.1016/j.cryobiol.2018.12.002. [Epub ahead of print]

PMID:
30527584
9.

Risky sexual behavior among adolescents: The role of decision-making, problems from cannabis use and externalizing disorder symptoms.

Ross JM, Granja K, Duperrouzel JC, Pacheco-Colón I, Lopez-Quintero C, Hawes SW, Gonzalez R.

J Clin Exp Neuropsychol. 2018 Dec 6:1-12. doi: 10.1080/13803395.2018.1550192. [Epub ahead of print]

PMID:
30520343
10.

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG; 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A.

Nat Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26.

PMID:
30482948
11.

Genetic suppression of cryoprotectant toxicity.

Cypser JR, Chick WS, Fahy GM, Schumacher GJ, Johnson TE.

Cryobiology. 2018 Nov 17. pii: S0011-2240(18)30266-9. doi: 10.1016/j.cryobiol.2018.11.003. [Epub ahead of print]

PMID:
30458175
12.

Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2* receptor expression and clustering.

Zambrano CA, Escobar D, Ramos-Santiago T, Bollinger I, Stitzel J.

Biochem Pharmacol. 2019 Jan;159:64-73. doi: 10.1016/j.bcp.2018.11.008. Epub 2018 Nov 9.

PMID:
30414940
13.

Predictors of adult outcomes in clinically- and legally-ascertained youth with externalizing problems.

Border R, Corley RP, Brown SA, Hewitt JK, Hopfer CJ, Stallings MC, Wall TL, Young SE, Rhee SH.

PLoS One. 2018 Nov 1;13(11):e0206442. doi: 10.1371/journal.pone.0206442. eCollection 2018.

14.

BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans.

Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N.

EMBO Rep. 2018 Dec;19(12). pii: e45856. doi: 10.15252/embr.201845856. Epub 2018 Oct 26.

PMID:
30366941
15.

The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI.

Do EK, Haberstick BC, Williams RB, Lessem JM, Smolen A, Siegler IC, Fuemmeler BF.

Int J Obes (Lond). 2019 Jan;43(1):33-42. doi: 10.1038/s41366-018-0236-5. Epub 2018 Oct 22.

PMID:
30349010
16.

Longitudinal Relations Between Depressive Symptoms and Executive Functions From Adolescence to Early Adulthood: A Twin Study.

Friedman NP, du Pont A, Corley RP, Hewitt JK.

Clin Psychol Sci. 2018 Jul;6(4):543-560. doi: 10.1177/2167702618766360. Epub 2018 May 18.

PMID:
30250762
17.

The Relationship Between Resting State Network Connectivity and Individual Differences in Executive Functions.

Reineberg AE, Gustavson DE, Benca C, Banich MT, Friedman NP.

Front Psychol. 2018 Sep 5;9:1600. doi: 10.3389/fpsyg.2018.01600. eCollection 2018.

18.

Enhancing and Extending Biological Performance and Resilience.

Leak RK, Calabrese EJ, Kozumbo WJ, Gidday JM, Johnson TE, Mitchell JR, Ozaki CK, Wetzker R, Bast A, Belz RG, Bøtker HE, Koch S, Mattson MP, Simon RP, Jirtle RL, Andersen ME.

Dose Response. 2018 Aug 15;16(3):1559325818784501. doi: 10.1177/1559325818784501. eCollection 2018 Jul-Sep. Review.

19.

A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction.

Coverstone ED, Bach RG, Chen L, Bierut LJ, Li AY, Lenzini PA, O'Neill HC, Spertus JA, Sucharov CC, Stitzel JA, Schilling JD, Cresci S.

Basic Res Cardiol. 2018 Aug 10;113(5):38. doi: 10.1007/s00395-018-0697-7.

PMID:
30097758
20.

Independent predictors of mortality in adolescents ascertained for conduct disorder and substance use problems, their siblings and community controls.

Border R, Corley RP, Brown SA, Hewitt JK, Hopfer CJ, McWilliams SK, Rhea SA, Shriver CL, Stallings MC, Wall TL, Woodward KE, Rhee SH.

Addiction. 2018 Nov;113(11):2107-2115. doi: 10.1111/add.14366. Epub 2018 Aug 9.

PMID:
30091161

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