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Tumori. 2016 Oct 13;102(5):e21-e24. doi: 10.5301/tj.5000523.

Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer.

Author information

1
Radiation Oncology Department, Centre Hospitalier Universitaire Vaudois - CHUV, Lausanne - Switzerland.
2
Current address: Radiotherapy Unit, Department of Translational Medicine, University of Piemonte Orientale, Novara - Italy.
3
Nuclear Medicine and Molecular Medicine Department, Centre Hospitalier Universitaire Vaudois - CHUV, Lausanne - Switzerland.
4
Medical Physics, Centre Hospitalier Universitaire Vaudois - CHUV, Lausanne - Switzerland.

Abstract

We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

PMID:
27443895
DOI:
10.5301/tj.5000523
[Indexed for MEDLINE]

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