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Emerg Infect Dis. 2007 Nov;13(11):1653-60. doi: 10.3201/eid1311.061369.

Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia.

Author information

1
Infectious Disease Department, Austin Health, Melbourne, Victoria, Australia. paul.johnson@austin.org.au

Abstract

Buruli ulcer (BU) occurs in >30 countries. The causative organism, Mycobacterium ulcerans, is acquired from the environment, but the exact mode of transmission is unknown. We investigated an outbreak of BU in a small coastal town in southeastern Australia and screened by PCR mosquitoes caught there. All cases of BU were confirmed by culture or PCR. Mosquitoes were trapped in multiple locations during a 26-month period. BU developed in 48 residents of Point Lonsdale/Queenscliff and 31 visitors from January 2001 through April 2007. We tested 11,504 mosquitoes trapped at Point Lonsdale (predominantly Aedes camptorhynchus). Forty-eight pools (5 species) were positive for insertion sequence IS2404 (maximum likelihood estimate 4.3/1,000), and we confirmed the presence of M. ulcerans in a subset of pools by detection of 3 additional PCR targets.

PMID:
18217547
PMCID:
PMC3375796
DOI:
10.3201/eid1311.061369
[Indexed for MEDLINE]
Free PMC Article

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