Format

Send to

Choose Destination
Am J Ophthalmol. 2005 Oct;140(4):612-7.

Population-based incidence of uveal melanoma in various races and ethnic groups.

Author information

1
Department of Pathology, New York Eye and Ear Infirmary, New York, New York 10003, USA. hu2095@yahoo.com

Abstract

PURPOSE:

To investigate racial/ethnic differences in the development of uveal malignant melanoma in a large population-based study.

DESIGN:

Observational cross-sectional study.

METHODS:

With the 1992 to 2000 data that was provided by the National Cancer Institute's Surveillance, Epidemiology, and End Results Program, we calculated age-adjusted incidence rates of uveal melanoma in various racial/ethnic groups (black, Asian and Pacific Islander, Hispanic, and non-Hispanic white). In addition, we calculated the standard incidence ratio (risk ratio) and 95% confidence interval to describe the differences within these racial/ethnic groups.

RESULTS:

From 1992 to 2000, there were a total of 1352 uveal melanomas that were diagnosed in 11 Surveillance, Epidemiology, and End Results registries with known racial/ethnic groups. The annual age-adjusted incidence (per million population) of uveal melanoma was 0.31 (black), 0.38 (Asian), 1.67 (Hispanic), and 6.02 (non-Hispanic white). The difference in the incidence of uveal melanoma between each racial/ethnic group was highly statistically significant, with the exception of the black versus the Asian population in which there was no statistically significant difference.

CONCLUSION:

The relative risk of uveal melanoma was 1.2 for Asian and Pacific Islander patients, 5.4 for Hispanic patients, and 19.2 for non-Hispanic white patients as compared with the black patients. If the non-Hispanic white population and the Hispanic population were combined, then the overall white:black ratio was 18:1.

PMID:
16226513
DOI:
10.1016/j.ajo.2005.05.034
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center