Format

Send to

Choose Destination
Bull World Health Organ. 2001;79(3):194-200. Epub 2003 Jul 7.

Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal.

Author information

1
Francis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA.

Abstract

OBJECTIVE:

The study compares the effectiveness of two strategies for distributing azithromycin in an area with mild-to-moderate active trachoma in Nepal.

METHODS:

The two strategies investigated were the use of azithromycin for 1) mass treatment of all children, or 2) targeted treatment of only those children who were found to be clinically active, as well as all members of their household.

FINDINGS:

Mass treatment of children was slightly more effective in terms of decreasing the prevalence of clinically active trachoma (estimated by clinical examination) and of chlamydial infection (estimated by DNA amplification tests), although neither result was statistically significant.

CONCLUSION:

Both strategies appeared to be effective in reducing the prevalence of clinically active trachoma and infection six months after the treatment. Antibiotic treatment reduced the prevalence of chlamydial infection more than it did the level of clinically active trachoma.

PMID:
11285662
PMCID:
PMC2566365
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Scientific Electronic Library Online Icon for PubMed Central
Loading ...
Support Center