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Genet Sel Evol. 2018 May 24;50(1):29. doi: 10.1186/s12711-018-0399-5.

Population structure and genetic diversity of 25 Russian sheep breeds based on whole-genome genotyping.

Author information

1
L.K. Ernst Federal Science Center for Animal Husbandry, Dubrovitzy Estate 60, Podolia, Russia, 142132. horarka@yandex.ru.
2
L.K. Ernst Federal Science Center for Animal Husbandry, Dubrovitzy Estate 60, Podolia, Russia, 142132.
3
All-Russian Research Institute of Sheep and Goat Breeding, Zootechnichesky Lane 15, Stavropol, Russia, 355017.
4
Population Genomics Group, Department of Veterinary Sciences, LMU Munich, Veterinaerstr. 13, 80539, Munich, Germany.
5
Institute of Genome Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany.
6
Istituto di Zootecnica, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122, Piacenza, Italy.
7
Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Vienna, Austria.
8
L.K. Ernst Federal Science Center for Animal Husbandry, Dubrovitzy Estate 60, Podolia, Russia, 142132. n_zinovieva@mail.ru.

Abstract

BACKGROUND:

Russia has a diverse variety of native and locally developed sheep breeds with coarse, fine, and semi-fine wool, which inhabit different climate zones and landscapes that range from hot deserts to harsh northern areas. To date, no genome-wide information has been used to investigate the history and genetic characteristics of the extant local Russian sheep populations. To infer the population structure and genome-wide diversity of Russian sheep, 25 local breeds were genotyped with the OvineSNP50 BeadChip. Furthermore, to evaluate admixture contributions from foreign breeds in Russian sheep, a set of 58 worldwide breeds from publicly available genotypes was added to our data.

RESULTS:

We recorded similar observed heterozygosity (0.354-0.395) and allelic richness (1.890-1.955) levels across the analyzed breeds and they are comparable with those observed in the worldwide breeds. Recent effective population sizes estimated from linkage disequilibrium five generations ago ranged from 65 to 543. Multi-dimensional scaling, admixture, and neighbor-net analyses consistently identified a two-step subdivision of the Russian local sheep breeds. A first split clustered the Russian sheep populations according to their wool type (fine wool, semi-fine wool and coarse wool). The Dagestan Mountain and Baikal fine-fleeced breeds differ from the other Merino-derived local breeds. The semi-fine wool cluster combined a breed of Romanian origin, Tsigai, with its derivative Altai Mountain, the two Romney-introgressed breeds Kuibyshev and North Caucasian, and the Lincoln-introgressed Russian longhaired breed. The coarse-wool group comprised the Nordic short-tailed Romanov, the long-fat-tailed outlier Kuchugur and two clusters of fat-tailed sheep: the Caucasian Mountain breeds and the Buubei, Karakul, Edilbai, Kalmyk and Tuva breeds. The Russian fat-tailed breeds shared co-ancestry with sheep from China and Southwestern Asia (Iran).

CONCLUSIONS:

In this study, we derived the genetic characteristics of the major Russian local sheep breeds, which are moderately diverse and have a strong population structure. Pooling our data with a worldwide genotyping set gave deeper insight into the history and origin of the Russian sheep populations.

PMID:
29793424
PMCID:
PMC5968526
DOI:
10.1186/s12711-018-0399-5
[Indexed for MEDLINE]
Free PMC Article

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