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Items: 1 to 20 of 53


The Aryl Hydrocarbon Receptor: Connecting Immunity to the Microenvironment.

Shinde R, McGaha TL.

Trends Immunol. 2018 Dec;39(12):1005-1020. doi: 10.1016/ Epub 2018 Nov 5. Review.


CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity.

Snell LM, MacLeod BL, Law JC, Osokine I, Elsaesser HJ, Hezaveh K, Dickson RJ, Gavin MA, Guidos CJ, McGaha TL, Brooks DG.

Immunity. 2018 Oct 16;49(4):678-694.e5. doi: 10.1016/j.immuni.2018.08.002. Epub 2018 Oct 9.


Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.

Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, Chaudhary K, Munn DH, Tsirigos A, Madaio M, Gabrielsson S, Touma Z, Wither J, De Carvalho DD, McGaha TL.

Nat Immunol. 2018 Jun;19(6):571-582. doi: 10.1038/s41590-018-0107-1. Epub 2018 May 14.


Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment.

Johnson TS, Mcgaha T, Munn DH.

Adv Exp Med Biol. 2017;1036:91-104. doi: 10.1007/978-3-319-67577-0_7. Review.


Synthesis, characterization, and cellular localization of a fluorescent probe of the antimalarial 8-aminoquinoline primaquine.

McQueen A, Blake LD, Azhari A, Kemp MT, McGaha TW Jr, Namelikonda N, Larsen RW, Manetsch R, Kyle DE.

Bioorg Med Chem Lett. 2017 Oct 15;27(20):4597-4600. doi: 10.1016/j.bmcl.2017.09.030. Epub 2017 Sep 14.


Type I Interferon in Chronic Virus Infection and Cancer.

Snell LM, McGaha TL, Brooks DG.

Trends Immunol. 2017 Aug;38(8):542-557. doi: 10.1016/ Epub 2017 May 31. Review.


Identification of semiochemicals attractive to Simulium vittatum (IS-7).

Verocai GG, McGAHA TW Jr, Iburg JP, Katholi CR, Cupp EW, Noblet R, Unnasch TR.

Med Vet Entomol. 2017 Jun;31(2):140-149. doi: 10.1111/mve.12218. Epub 2016 Dec 2.


Selective Memory to Apoptotic Cell-Derived Self-Antigens with Implications for Systemic Lupus Erythematosus Development.

Duhlin A, Chen Y, Wermeling F, Sedimbi SK, Lindh E, Shinde R, Halaby MJ, Kaiser Y, Winqvist O, McGaha TL, Karlsson MC.

J Immunol. 2016 Oct 1;197(7):2618-26. doi: 10.4049/jimmunol.1401129. Epub 2016 Aug 24.


An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis.

Sivaprakasam S, Gurav A, Paschall AV, Coe GL, Chaudhary K, Cai Y, Kolhe R, Martin P, Browning D, Huang L, Shi H, Sifuentes H, Vijay-Kumar M, Thompson SA, Munn DH, Mellor A, McGaha TL, Shiao P, Cutler CW, Liu K, Ganapathy V, Li H, Singh N.

Oncogenesis. 2016 Jun 27;5(6):e238. doi: 10.1038/oncsis.2016.38.


The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment.

Sharma MD, Shinde R, McGaha TL, Huang L, Holmgaard RB, Wolchok JD, Mautino MR, Celis E, Sharpe AH, Francisco LM, Powell JD, Yagita H, Mellor AL, Blazar BR, Munn DH.

Sci Adv. 2015 Nov 6;1(10):e1500845. doi: 10.1126/sciadv.1500845. eCollection 2015 Nov.


IDO-GCN2 and autophagy in inflammation.

McGaha TL.

Oncotarget. 2015 Sep 8;6(26):21771-2. No abstract available.


The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.

Ravishankar B, Liu H, Shinde R, Chaudhary K, Xiao W, Bradley J, Koritzinsky M, Madaio MP, McGaha TL.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10774-9. doi: 10.1073/pnas.1504276112. Epub 2015 Aug 10.


B Cell-Intrinsic IDO1 Regulates Humoral Immunity to T Cell-Independent Antigens.

Shinde R, Shimoda M, Chaudhary K, Liu H, Mohamed E, Bradley J, Kandala S, Li X, Liu K, McGaha TL.

J Immunol. 2015 Sep 1;195(5):2374-82. doi: 10.4049/jimmunol.1402854. Epub 2015 Jul 27.


Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy.

Chaudhary K, Shinde R, Liu H, Gnana-Prakasam JP, Veeranan-Karmegam R, Huang L, Ravishankar B, Bradley J, Kvirkvelia N, McMenamin M, Xiao W, Kleven D, Mellor AL, Madaio MP, McGaha TL.

J Immunol. 2015 Jun 15;194(12):5713-24. doi: 10.4049/jimmunol.1500277. Epub 2015 May 15.


Identification of communal oviposition pheromones from the black fly Simulium vittatum.

McGaha TW Jr, Young RM, Burkett-Cadena ND, Iburg JP, Beau JM, Hassan S, Katholi CR, Cupp EW, Baker BJ, Unnasch TR, Noblet R.

PLoS One. 2015 Mar 18;10(3):e0118904. doi: 10.1371/journal.pone.0118904. eCollection 2015.


Lupus Nephritis: Animal Modeling of a Complex Disease Syndrome Pathology.

McGaha TL, Madaio MP.

Drug Discov Today Dis Models. 2014 Spring;11:13-18.


IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.

Paschall AV, Zhang R, Qi CF, Bardhan K, Peng L, Lu G, Yang J, Merad M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse HC 3rd, Ozato K, Xiong H, Liu K.

J Immunol. 2015 Mar 1;194(5):2369-79. doi: 10.4049/jimmunol.1402412. Epub 2015 Feb 2.


Screening for methicillin-resistant Staphylococcus aureus colonization using sponges.

Lee CS, Montalmont B, O'Hara JA, Syed A, Chaussard C, McGaha TL, Pakstis DL, Lee JH, Shutt KA, Doi Y.

Infect Control Hosp Epidemiol. 2015 Jan;36(1):28-33. doi: 10.1017/ice.2014.4.


Identification of human semiochemicals attractive to the major vectors of onchocerciasis.

Young RM, Burkett-Cadena ND, McGaha TW Jr, Rodriguez-Perez MA, ToƩ LD, Adeleke MA, Sanfo M, Soungalo T, Katholi CR, Noblet R, Fadamiro H, Torres-Estrada JL, Salinas-Carmona MC, Baker B, Unnasch TR, Cupp EW.

PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3450. doi: 10.1371/journal.pntd.0003450. eCollection 2015 Jan.

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