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Items: 1 to 20 of 106


Preclinical assessment of an antibody-PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells.

Kinneer K, Flynn M, Thomas SB, Meekin J, Varkey R, Xiao X, Zhong H, Breen S, Hynes PG, Fleming R, Bezabeh B, Chen CT, Wetzel L, Chen R, Dimasi N, Tai YT, Anderson KC, Herbst R, Howard PW, Hurt EM, Tice DA.

Leukemia. 2018 Oct 12. doi: 10.1038/s41375-018-0278-7. [Epub ahead of print] No abstract available.


Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer.

Bosco EE, Christie RJ, Carrasco R, Sabol D, Zha J, DaCosta K, Brown L, Kennedy M, Meekin J, Phipps S, Ayriss J, Du Q, Bezabeh B, Chowdhury P, Breen S, Chen C, Reed M, Hinrichs M, Zhong H, Xiao Z, Dixit R, Herbst R, Tice DA.

Oncotarget. 2018 May 1;9(33):22960-22975. doi: 10.18632/oncotarget.25160. eCollection 2018 May 1.


Barriers to implementing the Sepsis Six guidelines in an acute hospital setting.

Breen SJ, Rees S.

Br J Nurs. 2018 May 10;27(9):473-478. doi: 10.12968/bjon.2018.27.9.473.


Image registration assessment in radiotherapy image guidance based on control chart monitoring.

Xia W, Breen SL.

J Med Imaging (Bellingham). 2018 Apr;5(2):021221. doi: 10.1117/1.JMI.5.2.021221. Epub 2018 Mar 14.


Considering Culture: A Review of Pediatric Behavioral Intervention Research in Type 1 Diabetes.

Rose M, Aronow L, Breen S, Tully C, Hilliard ME, Butler AM, Streisand R.

Curr Diab Rep. 2018 Feb 23;18(4):16. doi: 10.1007/s11892-018-0987-3. Review.


Loss of AvrSr50 by somatic exchange in stem rust leads to virulence for Sr50 resistance in wheat.

Chen J, Upadhyaya NM, Ortiz D, Sperschneider J, Li F, Bouton C, Breen S, Dong C, Xu B, Zhang X, Mago R, Newell K, Xia X, Bernoux M, Taylor JM, Steffenson B, Jin Y, Zhang P, Kanyuka K, Figueroa M, Ellis JG, Park RF, Dodds PN.

Science. 2017 Dec 22;358(6370):1607-1610. doi: 10.1126/science.aao4810.


Mobile Health Intervention to Increase Oral Cancer Therapy Adherence in Patients With Chronic Myeloid Leukemia (The REMIND System): Clinical Feasibility and Acceptability Assessment.

Pereira-Salgado A, Westwood JA, Russell L, Ugalde A, Ortlepp B, Seymour JF, Butow P, Cavedon L, Ong K, Aranda S, Breen S, Kirsa S, Dunlevie A, Schofield P.

JMIR Mhealth Uhealth. 2017 Dec 6;5(12):e184. doi: 10.2196/mhealth.8349.


The experiences of patients with advanced cancer and caregivers presenting to Emergency Departments: A qualitative study.

Philip J, Remedios C, Breen S, Weiland T, Willenberg L, Boughey M, Jelinek G, Lane H, Marck C, Weil J.

Palliat Med. 2018 Feb;32(2):439-446. doi: 10.1177/0269216317735724. Epub 2017 Nov 13.


Brachytherapy patient safety events in an academic radiation medicine program.

Felder S, Morley L, Ng E, Chan K, Ballantyne H, Di Tomasso A, Borg J, Bissonnette JP, Breen S, Waldron J, Rink A, Milosevic M.

Brachytherapy. 2018 Jan - Feb;17(1):16-23. doi: 10.1016/j.brachy.2017.06.010. Epub 2017 Jul 27.


Emerging Insights into the Functions of Pathogenesis-Related Protein 1.

Breen S, Williams SJ, Outram M, Kobe B, Solomon PS.

Trends Plant Sci. 2017 Oct;22(10):871-879. doi: 10.1016/j.tplants.2017.06.013. Epub 2017 Jul 22. Review.


Fractionated Dosing Improves Preclinical Therapeutic Index of Pyrrolobenzodiazepine-Containing Antibody Drug Conjugates.

Hinrichs MJM, Ryan PM, Zheng B, Afif-Rider S, Yu XQ, Gunsior M, Zhong H, Harper J, Bezabeh B, Vashisht K, Rebelatto M, Reed M, Ryan PC, Breen S, Patel N, Chen C, Masterson L, Tiberghien A, Howard PW, Dimasi N, Dixit R.

Clin Cancer Res. 2017 Oct 1;23(19):5858-5868. doi: 10.1158/1078-0432.CCR-17-0219. Epub 2017 Jun 19.


Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.

Harper J, Lloyd C, Dimasi N, Toader D, Marwood R, Lewis L, Bannister D, Jovanovic J, Fleming R, D'Hooge F, Mao S, Marrero AM, Korade M 3rd, Strout P, Xu L, Chen C, Wetzel L, Breen S, van Vlerken-Ysla L, Jalla S, Rebelatto M, Zhong H, Hurt EM, Hinrichs MJ, Huang K, Howard PW, Tice DA, Hollingsworth RE, Herbst R, Kamal A.

Mol Cancer Ther. 2017 Aug;16(8):1576-1587. doi: 10.1158/1535-7163.MCT-16-0825. Epub 2017 May 18.


Utility values associated with advanced or metastatic non-small cell lung cancer: data needs for economic modeling.

Brown J, Cook K, Adamski K, Lau J, Bargo D, Breen S, Chawla A.

Expert Rev Pharmacoecon Outcomes Res. 2017 Apr;17(2):153-164. doi: 10.1080/14737167.2017.1311210. Review.


RXLR Effector AVR2 Up-Regulates a Brassinosteroid-Responsive bHLH Transcription Factor to Suppress Immunity.

Turnbull D, Yang L, Naqvi S, Breen S, Welsh L, Stephens J, Morris J, Boevink PC, Hedley PE, Zhan J, Birch PRJ, Gilroy EM.

Plant Physiol. 2017 May;174(1):356-369. doi: 10.1104/pp.16.01804. Epub 2017 Mar 7.


Effect of Standard Radiotherapy With Cisplatin vs Accelerated Radiotherapy With Panitumumab in Locoregionally Advanced Squamous Cell Head and Neck Carcinoma: A Randomized Clinical Trial.

Siu LL, Waldron JN, Chen BE, Winquist E, Wright JR, Nabid A, Hay JH, Ringash J, Liu G, Johnson A, Shenouda G, Chasen M, Pearce A, Butler JB, Breen S, Chen EX, FitzGerald TJ, Childs TJ, Montenegro A, O'Sullivan B, Parulekar WR.

JAMA Oncol. 2016 Dec 8. doi: 10.1001/jamaoncol.2016.4510. [Epub ahead of print]


Wheat PR-1 proteins are targeted by necrotrophic pathogen effector proteins.

Breen S, Williams SJ, Winterberg B, Kobe B, Solomon PS.

Plant J. 2016 Oct;88(1):13-25. doi: 10.1111/tpj.13228. Epub 2016 Aug 10.


Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies.

Zhong H, Fazenbaker C, Chen C, Breen S, Huang J, Yao X, Ren P, Yao Y, Herbst R, Hollingsworth RE.

Oncogene. 2017 Feb 9;36(6):797-806. doi: 10.1038/onc.2016.248. Epub 2016 Jul 11.


Differential effector gene expression underpins epistasis in a plant fungal disease.

Phan HT, Rybak K, Furuki E, Breen S, Solomon PS, Oliver RP, Tan KC.

Plant J. 2016 Aug;87(4):343-54. doi: 10.1111/tpj.13203. Epub 2016 Jul 7.


Production of small cysteine-rich effector proteins in Escherichia coli for structural and functional studies.

Zhang X, Nguyen N, Breen S, Outram MA, Dodds PN, Kobe B, Solomon PS, Williams SJ.

Mol Plant Pathol. 2017 Jan;18(1):141-151. doi: 10.1111/mpp.12385. Epub 2016 Apr 12.


A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.

Zhong H, Davis A, Ouzounova M, Carrasco RA, Chen C, Breen S, Chang YS, Huang J, Liu Z, Yao Y, Hurt E, Moisan J, Fung M, Tice DA, Clouthier SG, Xiao Z, Wicha MS, Korkaya H, Hollingsworth RE.

Cancer Res. 2016 Jan 15;76(2):480-90. doi: 10.1158/0008-5472.CAN-15-0883. Epub 2016 Jan 7.

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