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Sapropterin reduces coronary artery malformation in offspring of pregestational diabetes mice.

Engineer A, Lim YJ, Lu X, Norozi K, Feng Q.

Nitric Oxide. 2019 Oct 7. pii: S1089-8603(19)30180-6. doi: 10.1016/j.niox.2019.10.002. [Epub ahead of print]


Say NO to ROS: Their Roles in Embryonic Heart Development and Pathogenesis of Congenital Heart Defects in Maternal Diabetes.

Engineer A, Saiyin T, Greco ER, Feng Q.

Antioxidants (Basel). 2019 Oct 1;8(10). pii: E436. doi: 10.3390/antiox8100436. Review.


Maternal voluntary exercise mitigates oxidative stress and incidence of congenital heart defects in pre-gestational diabetes.

Saiyin T, Engineer A, Greco ER, Kim MY, Lu X, Jones DL, Feng Q.

J Cell Mol Med. 2019 Aug;23(8):5553-5565. doi: 10.1111/jcmm.14439. Epub 2019 Jun 18.


Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice.

Novielli-Kuntz NM, Jelen M, Barr K, DeLalio LJ, Feng Q, Isakson BE, Gros R, Laird DW.

Biosci Rep. 2019 Feb 27;39(2). pii: BSR20182350. doi: 10.1042/BSR20182350. Print 2019 Feb 28.


Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes Mellitus in Mice.

Engineer A, Saiyin T, Lu X, Kucey AS, Urquhart BL, Drysdale TA, Norozi K, Feng Q.

J Am Heart Assoc. 2018 Nov 6;7(21):e009624. doi: 10.1161/JAHA.118.009624.


Bicuspid aortic valve formation: Nos3 mutation leads to abnormal lineage patterning of neural crest cells and the second heart field.

Peterson JC, Chughtai M, Wisse LJ, Gittenberger-de Groot AC, Feng Q, Goumans MTH, VanMunsteren JC, Jongbloed MRM, DeRuiter MC.

Dis Model Mech. 2018 Oct 19;11(10). pii: dmm034637. doi: 10.1242/dmm.034637.


S-Nitrosylation of STIM1 by Neuronal Nitric Oxide Synthase Inhibits Store-Operated Ca2+ Entry.

Gui L, Zhu J, Lu X, Sims SM, Lu WY, Stathopulos PB, Feng Q.

J Mol Biol. 2018 Jun 8;430(12):1773-1785. doi: 10.1016/j.jmb.2018.04.028. Epub 2018 Apr 27.


Structural elements of stromal interaction molecule function.

Novello MJ, Zhu J, Feng Q, Ikura M, Stathopulos PB.

Cell Calcium. 2018 Jul;73:88-94. doi: 10.1016/j.ceca.2018.04.006. Epub 2018 Apr 18. Review.


A charge-sensing region in the stromal interaction molecule 1 luminal domain confers stabilization-mediated inhibition of SOCE in response to S-nitrosylation.

Zhu J, Lu X, Feng Q, Stathopulos PB.

J Biol Chem. 2018 Jun 8;293(23):8900-8911. doi: 10.1074/jbc.RA117.000503. Epub 2018 Apr 16.


Maternal diabetes up-regulates NOX2 and enhances myocardial ischaemia/reperfusion injury in adult offspring.

Zhang L, Wang X, Wu Y, Lu X, Chidiac P, Wang G, Feng Q.

J Cell Mol Med. 2018 Apr;22(4):2200-2209. doi: 10.1111/jcmm.13500. Epub 2018 Jan 29.


Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium.

Blom JN, Feng Q.

Pharmacol Ther. 2018 Jun;186:114-129. doi: 10.1016/j.pharmthera.2018.01.002. Epub 2018 Jan 17. Review.


Activation of transient receptor potential vanilloid 1 protects the heart against apoptosis in ischemia/reperfusion injury through upregulating the PI3K/Akt signaling pathway.

Jiang XX, Liu GY, Lei H, Li ZL, Feng QP, Huang W.

Int J Mol Med. 2018 Mar;41(3):1724-1730. doi: 10.3892/ijmm.2017.3338. Epub 2017 Dec 21.


Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins.

Choi YJ, Zhu J, Chung S, Siddiqui N, Feng Q, Stathopulos PB.

J Vis Exp. 2017 Oct 4;(128). doi: 10.3791/56302.


The STIM-Orai Pathway: STIM-Orai Structures: Isolated and in Complex.

Zhu J, Feng Q, Stathopulos PB.

Adv Exp Med Biol. 2017;993:15-38. doi: 10.1007/978-3-319-57732-6_2. Review.


Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice.

Tyml K, Swarbreck S, Pape C, Secor D, Koropatnick J, Feng Q, Veldhuizen RAW, Gill SE.

Crit Care. 2017 Aug 8;21(1):210. doi: 10.1186/s13054-017-1783-1.


Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice.

Lee KN, Lu X, Nguyen C, Feng Q, Chidiac P.

J Mol Cell Cardiol. 2017 Jul;108:194-202. doi: 10.1016/j.yjmcc.2017.06.007. Epub 2017 Jun 19.


Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes.

Feng AL, Xiang YY, Gui L, Kaltsidis G, Feng Q, Lu WY.

Diabetologia. 2017 Jun;60(6):1033-1042. doi: 10.1007/s00125-017-4239-x. Epub 2017 Mar 9.


North American ginseng inhibits myocardial NOX2-ERK1/2 signaling and tumor necrosis factor-α expression in endotoxemia.

Wu Y, Qin C, Lu X, Marchiori J, Feng Q.

Pharmacol Res. 2016 Sep;111:217-225. doi: 10.1016/j.phrs.2016.06.010. Epub 2016 Jun 16.


Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration.

Blom JN, Lu X, Arnold P, Feng Q.

J Vis Exp. 2016 May 24;(111). doi: 10.3791/54100.


Inhibition of Rac1 reduces store overload-induced calcium release and protects against ventricular arrhythmia.

Zhang L, Lu X, Gui L, Wu Y, Sims SM, Wang G, Feng Q.

J Cell Mol Med. 2016 Aug;20(8):1513-22. doi: 10.1111/jcmm.12840. Epub 2016 May 25.

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