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Managing Risks with Biologics.

Click B, Regueiro M.

Curr Gastroenterol Rep. 2019 Jan 11;21(2):1. doi: 10.1007/s11894-019-0669-6. Review.


Increased prevalence of anti-TNF therapy in paediatric inflammatory bowel disease is associated with a decline in surgical resections during childhood.

Ashton JJ, Borca F, Mossotto E, Coelho T, Batra A, Afzal NA, Phan HTT, Stanton M, Ennis S, Beattie RM.

Aliment Pharmacol Ther. 2019 Jan 9. doi: 10.1111/apt.15094. [Epub ahead of print]


Shorter Disease Duration is Associated With Higher Rates of Response to Vedolizumab in Patients With Crohn's Disease but Not Ulcerative Colitis.

Faleck DM, Winters A, Chablaney S, Shashi P, Meserve J, Weiss A, Aniwan S, Koliani-Pace JL, Kochhar G, Boland B, Singh S, Hirten R, Shmidt E, Kesar V, Lasch K, Luo M, Bohm M, Varma S, Fischer M, Hudesman D, Chang S, Lukin D, Sultan K, Swaminath A, Gupta N, Siegel CA, Shen B, Sandborn WJ, Kane S, Loftus EV Jr, Sands BE, Colombel JF, Dulai PS, Ungaro R.

Clin Gastroenterol Hepatol. 2019 Jan 5. pii: S1542-3565(19)30013-8. doi: 10.1016/j.cgh.2018.12.040. [Epub ahead of print]


Evaluation of Home Polysomnography Findings, Quality of Sleep, and Fatigue in Inflammatory Bowel Disease: A Case Series.

Paixão DL, Poyares D, de Paula MS, Duarte JW, Castelo PM, Ambrogini-Júnior O, Miszputen SJ, Oshima CTF, Chagas JR, Paiotti APR.

J Clin Sleep Med. 2019 Jan 3. pii: jc-18-00083. [Epub ahead of print]


Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress.

El-Akabawy G, El-Sherif NM.

Biomed Pharmacother. 2019 Jan 4;111:841-851. doi: 10.1016/j.biopha.2019.01.001. [Epub ahead of print]


LB-9, Novel Probiotic Lactic Acid Bacteria, Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mice by Inhibiting TNF-α-Mediated Apoptosis of Intestinal Epithelial Cells.

Chae JM, Chang MH, Heo W, Cho HT, Lee DH, Hwang BB, Kim JW, Yoon SM, Yang S, Lee JH, Kim YJ.

J Med Food. 2019 Jan 7. doi: 10.1089/jmf.2018.4236. [Epub ahead of print]


Polymerase chain reaction for detection of mucosal cytomegalovirus infection in patients with acute ulcerative colitis.

Tun GSZ, Raza M, Hale MF, Lobo AJ.

Ann Gastroenterol. 2019 Jan-Feb;32(1):81-87. doi: 10.20524/aog.2018.0318. Epub 2018 Oct 3.


Mucosal Immunity Related to FOXP3+ Regulatory T Cells, Th17 Cells and Cytokines in Pediatric Inflammatory Bowel Disease.

Cho J, Kim S, Yang DH, Lee J, Park KW, Go J, Hyun CL, Jee Y, Kang KS.

J Korean Med Sci. 2018 Dec 10;33(52):e336. doi: 10.3346/jkms.2018.33.e336. eCollection 2018 Dec 24.


MicroRNA-15a - cell division cycle 42 signaling pathway in pathogenesis of pediatric inflammatory bowel disease.

Tang WJ, Peng KY, Tang ZF, Wang YH, Xue AJ, Huang Y.

World J Gastroenterol. 2018 Dec 14;24(46):5234-5245. doi: 10.3748/wjg.v24.i46.5234.


Bispecific antibodies: The next generation of targeted inflammatory bowel disease therapies.

Peyrin-Biroulet L, Demarest S, Nirula A.

Autoimmun Rev. 2018 Dec 17. pii: S1568-9972(18)30283-0. doi: 10.1016/j.autrev.2018.07.014. [Epub ahead of print] Review.


Do Androgens Modulate the Pathophysiological Pathways of Inflammation? Appraising the Contemporary Evidence.

Traish A, Bolanos J, Nair S, Saad F, Morgentaler A.

J Clin Med. 2018 Dec 14;7(12). pii: E549. doi: 10.3390/jcm7120549. Review.


Association study between two polymorphisms of tumor necrosis factor ligand superfamily member 15 (TNFSF15) gene and ulcerative colitis in south-west of Iran.

Taheri M, Ghandil P, Hashemi SJ, Ghafourian M, Masjedi Zadeh AR, Ghadiri AA.

J Cell Biochem. 2018 Dec 16. doi: 10.1002/jcb.28165. [Epub ahead of print]


Effectiveness of golimumab in ulcerative colitis: A review of the real world evidence.

Olivera P, Danese S, Pouillon L, Bonovas S, Peyrin-Biroulet L.

Dig Liver Dis. 2018 Nov 16. pii: S1590-8658(18)31221-0. doi: 10.1016/j.dld.2018.11.002. [Epub ahead of print] Review.


Effect of compound sophorae decoction on dextran sodium sulfate (DSS)-induced colitis in mice by regulating Th17/Treg cell balance.

Xu M, Duan XY, Chen QY, Fan H, Hong ZC, Deng SJ, Nan Z, Wu H, Dong YL, Liu YJ, Zhou CZ.

Biomed Pharmacother. 2019 Jan;109:2396-2408. doi: 10.1016/j.biopha.2018.11.087. Epub 2018 Nov 30.


Incidence and clinical impact of perianal disease in patients with ulcerative colitis: A nationwide population-based study.

Song EM, Lee HS, Kim YJ, Oh EH, Ham NS, Kim J, Hwang SW, Park SH, Yang DH, Ye BD, Byeon JS, Myung SJ, Yang SK.

J Gastroenterol Hepatol. 2018 Nov 22. doi: 10.1111/jgh.14555. [Epub ahead of print]


The inhibitory effects of Qingchang Wenzhong granule on the interactive network of inflammation, oxidative stress, and apoptosis in rats with dextran sulfate sodium-induced colitis.

Shi L, Dai Y, Jia B, Han Y, Guo Y, Xie T, Liu J, Tan X, Ding P, Li J.

J Cell Biochem. 2018 Dec 11. doi: 10.1002/jcb.28280. [Epub ahead of print]


Multiple Cytokine Profiling: A New Model to Predict Response to Tumor Necrosis Factor Antagonists in Ulcerative Colitis Patients.

Obraztsov IV, Shirokikh KE, Obraztsova OI, Shapina MV, Wang MH, Khalif IL.

Inflamm Bowel Dis. 2018 Dec 13. doi: 10.1093/ibd/izy358. [Epub ahead of print]


Targeting Nrf2/HO-1 signaling by crocin: Role in attenuation of AA-induced ulcerative colitis in rats.

Khodir AE, Said E, Atif H, ElKashef HA, Salem HA.

Biomed Pharmacother. 2019 Feb;110:389-399. doi: 10.1016/j.biopha.2018.11.133. Epub 2018 Dec 5.


Upfront Combination Therapy, Compared with Monotherapy, for Patients Not Previously Treated with a Biologic Agent Associates With Reduced Risk of Inflammatory Bowel Disease-related Complications in a Population-based Cohort Study.

Targownik LE, Benchimol EI, Bernstein CN, Singh H, Lix ML, Tennakoon A, Leung S, Aviña A, Coward S, Jones J, Kaplan G, Murthy SK, Nguyen GC, Peña-Sánchez JN.

Clin Gastroenterol Hepatol. 2018 Nov 15. pii: S1542-3565(18)31246-1. doi: 10.1016/j.cgh.2018.11.003. [Epub ahead of print]


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