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Items: 1 to 20 of 91


Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease.

Chiba H, Kakuta Y, Kinouchi Y, Kawai Y, Watanabe K, Nagao M, Naito T, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Nagasaki M, Unno M, Shimosegawa T.

PLoS One. 2018 Mar 16;13(3):e0194036. doi: 10.1371/journal.pone.0194036. eCollection 2018.


Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice.

Pott J, Kabat AM, Maloy KJ.

Cell Host Microbe. 2018 Feb 14;23(2):191-202.e4. doi: 10.1016/j.chom.2017.12.017. Epub 2018 Jan 18.


rs2476601 polymorphism in PTPN22 is associated with Crohn's disease but not with ulcerative colitis: a meta-analysis of 16,838 cases and 13,356 controls.

Hedjoudje A, Cheurfa C, Briquez C, Zhang A, Koch S, Vuitton L.

Ann Gastroenterol. 2017;30(2):197-208. doi: 10.20524/aog.2017.0121. Epub 2017 Jan 5.


Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn's disease is a risk factor for disease relapse in Japanese patients.

Kakuta Y, Kimura T, Negoro K, Kuroha M, Shiga H, Endo K, Kinouchi Y, Shimosegawa T.

J Gastroenterol. 2017 Dec;52(12):1230-1239. doi: 10.1007/s00535-017-1322-5. Epub 2017 Feb 22.


Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis.

Keppner A, Malsure S, Nobile A, Auberson M, Bonny O, Hummler E.

Inflamm Bowel Dis. 2016 Dec;22(12):2824-2839.


The genetic burden of inflammatory bowel diseases: implications for the clinic?

Gabbani T, Deiana S, Annese AL, Lunardi S, Annese V.

Expert Rev Gastroenterol Hepatol. 2016 Jun 9:1-9. [Epub ahead of print]


HSPA6 is an ulcerative colitis susceptibility factor that is induced by cigarette smoke and protects intestinal epithelial cells by stabilizing anti-apoptotic Bcl-XL.

Regeling A, Imhann F, Volders HH, Blokzijl T, Bloks VW, Weersma RK, Dijkstra G, Faber KN.

Biochim Biophys Acta. 2016 Apr;1862(4):788-796. doi: 10.1016/j.bbadis.2016.01.020. Epub 2016 Jan 26.


Identification of critical variants within SLC44A4, an ulcerative colitis susceptibility gene identified in a GWAS in north Indians.

Gupta A, Thelma BK.

Genes Immun. 2016 Mar;17(2):105-9. doi: 10.1038/gene.2015.53. Epub 2016 Jan 7.


Immunopathogenesis of IBD: current state of the art.

de Souza HS, Fiocchi C.

Nat Rev Gastroenterol Hepatol. 2016 Jan;13(1):13-27. doi: 10.1038/nrgastro.2015.186. Epub 2015 Dec 2. Review.


Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease.

Sasaki MM, Skol AD, Hungate EA, Bao R, Huang L, Kahn SA, Allan JM, Brant SR, McGovern DP, Peter I, Silverberg MS, Cho JH, Kirschner BS, Onel K.

Inflamm Bowel Dis. 2016 Jan;22(1):20-7. doi: 10.1097/MIB.0000000000000610.


[Advances in research on ulcerative colitis].

Araki T, Toiyama Y, Tanaka K, Uchida K, Kusunoki M.

Nihon Geka Gakkai Zasshi. 2015 Mar;116(2):104-8. Japanese.


Immunogenetic biomarkers in inflammatory bowel diseases: role of the IBD3 region.

Muro M, López-Hernández R, Mrowiec A.

World J Gastroenterol. 2014 Nov 7;20(41):15037-48. doi: 10.3748/wjg.v20.i41.15037. Review.


Exome sequencing identifies DLG1 as a novel gene for potential susceptibility to Crohn's disease in a Chinese family study.

Xu S, Zhou F, Tao J, Song L, Ng SC, Wang X, Chen L, Yi F, Ran Z, Zhou R, Xia B.

PLoS One. 2014 Jun 17;9(6):e99807. doi: 10.1371/journal.pone.0099807. eCollection 2014.


Differential effect of vitamin D on NOD2- and TLR-induced cytokines in Crohn's disease.

Dionne S, Calderon MR, White JH, Memari B, Elimrani I, Adelson B, Piccirillo C, Seidman EG.

Mucosal Immunol. 2014 Nov;7(6):1405-15. doi: 10.1038/mi.2014.30. Epub 2014 Apr 30.


Inflammatory bowel disease: pathogenesis.

Zhang YZ, Li YY.

World J Gastroenterol. 2014 Jan 7;20(1):91-9. doi: 10.3748/wjg.v20.i1.91. Review.


Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks.

Babeu JP, Boudreau F.

World J Gastroenterol. 2014 Jan 7;20(1):22-30. doi: 10.3748/wjg.v20.i1.22. Review.


Expression of inflammatory genes in the colon of ulcerative colitis patients varies with activity both at the mRNA and protein level.

Verma R, Verma N, Paul J.

Eur Cytokine Netw. 2013 Jul-Sep;24(3):130-8. doi: 10.1684/ecn.2013.0343.


Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics.

Ventham NT, Kennedy NA, Nimmo ER, Satsangi J.

Gastroenterology. 2013 Aug;145(2):293-308. doi: 10.1053/j.gastro.2013.05.050. Epub 2013 Jun 8. Review.


Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody.

Zheng J, Yin J, Huang R, Petersen F, Yu X.

Hum Immunol. 2013 Aug;74(8):986-92. doi: 10.1016/j.humimm.2013.04.034. Epub 2013 Apr 27.


Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation.

Levison SE, Fisher P, Hankinson J, Zeef L, Eyre S, Ollier WE, McLaughlin JT, Brass A, Grencis RK, Pennock JL.

BMC Genomics. 2013 Feb 26;14:127. doi: 10.1186/1471-2164-14-127.

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