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Items: 1 to 20 of 69


Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells.

Ruan H, Zhan YY, Hou J, Xu B, Chen B, Tian Y, Wu D, Zhao Y, Zhang Y, Chen X, Mi P, Zhang L, Zhang S, Wang X, Cao H, Zhang W, Wang H, Li H, Su Y, Zhang XK, Hu T.

Oncogene. 2017 Dec 14;36(50):6906-6918. doi: 10.1038/onc.2017.296. Epub 2017 Aug 28.


Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues.

Zhang B, Madden P, Gu J, Xing X, Sankar S, Flynn J, Kroll K, Wang T.

BMC Genomics. 2017 Jun 5;18(1):439. doi: 10.1186/s12864-017-3813-4.


Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRα by K48/K63-linked polyubiquitination.

Shi WN, Cui SX, Song ZY, Wang SQ, Sun SY, Yu XF, Li Y, Zhang YH, Gao ZH, Qu XJ.

Oncotarget. 2017 Jun 13;8(24):39605-39617. doi: 10.18632/oncotarget.17174.


Green Tea Polyphenols Inhibit Colorectal Tumorigenesis in Azoxymethane-Treated F344 Rats.

Hao X, Xiao H, Ju J, Lee MJ, Lambert JD, Yang CS.

Nutr Cancer. 2017 May-Jun;69(4):623-631. doi: 10.1080/01635581.2017.1295088. Epub 2017 Mar 21.


Bioactivity of Carotenoids - Chasms of Knowledge.

Bohn T.

Int J Vitam Nutr Res. 2017 Feb 10:1-5. doi: 10.1024/0300-9831/a000400. [Epub ahead of print]


Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat.

Hao X, Xiao H, Ju J, Hewitt SM, Morse HC 3rd.

Anticancer Res. 2016 Jun;36(6):2659-64.


Reduction in promotor methylation utilizing EGCG (epigallocatechin-3-gallate) restores RXRα expression in human colon cancer cells.

Morris J, Moseley VR, Cabang AB, Coleman K, Wei W, Garrett-Mayer E, Wargovich MJ.

Oncotarget. 2016 Jun 7;7(23):35313-26. doi: 10.18632/oncotarget.9204.


Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells.

Mumcuoglu M, Gurkan-Alp AS, Buyukbingol E, Cetin-Atalay R.

Steroids. 2016 Apr;108:31-8. doi: 10.1016/j.steroids.2016.02.008. Epub 2016 Feb 17.


Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization.

Courtaut F, Derangère V, Chevriaux A, Ladoire S, Cotte AK, Arnould L, Boidot R, Rialland M, Ghiringhelli F, Rébé C.

Oncotarget. 2015 Sep 29;6(29):26651-62. doi: 10.18632/oncotarget.5791.


Epigallocatechin-3-gallate Increases RXRγ-mediated Pro-apoptotic and Anti-invasive Effects in Gastrointestinal Cancer Cell Lines.

Papi A, Govoni M, Ciavarella C, Spisni E, Orlandi M, Farabegoli F.

Curr Cancer Drug Targets. 2016;16(4):373-85.


Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas.

Giardina C, Nakanishi M, Khan A, Kuratnik A, Xu W, Brenner B, Rosenberg DW.

Cancer Prev Res (Phila). 2015 May;8(5):387-99. doi: 10.1158/1940-6207.CAPR-14-0371. Epub 2015 Apr 14.


Restoration of the anti-proliferative and anti-migratory effects of 1,25-dihydroxyvitamin D by silibinin in vitamin D-resistant colon cancer cells.

Bhatia V, Falzon M.

Cancer Lett. 2015 Jul 1;362(2):199-207. doi: 10.1016/j.canlet.2015.03.042. Epub 2015 Apr 3.


Down-regulation of LXR/RXR activation and negative acute phase response pathways in colon adenocarcinoma revealed by proteomics and bioinformatics analysis.

Tang H, Mirshahidi S, Senthil M, Kazanjian K, Chen CS, Zhang K.

Cancer Biomark. 2014;14(5):313-24. doi: 10.3233/CBM-140409.


Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation.

Leung WH, Vong QP, Lin W, Janke L, Chen T, Leung W.

J Exp Med. 2013 Nov 18;210(12):2675-92. doi: 10.1084/jem.20122292. Epub 2013 Nov 4.


Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.

Janakiram NB, Mohammed A, Zhang Y, Brewer M, Bryant T, Lightfoot S, Steele VE, Rao CV.

Cancer Prev Res (Phila). 2013 Dec;6(12):1251-61. doi: 10.1158/1940-6207.CAPR-13-0249. Epub 2013 Sep 30.


Vitamin D receptor and retinoid X receptor α status and vitamin D insufficiency in models of murine colitis.

Knackstedt RW, Moseley VR, Sun S, Wargovich MJ.

Cancer Prev Res (Phila). 2013 Jun;6(6):585-93. doi: 10.1158/1940-6207.CAPR-12-0488. Epub 2013 Apr 12.


Pregnane X receptor and human malignancy.

Koutsounas I, Patsouris E, Theocharis S.

Histol Histopathol. 2013 Apr;28(4):405-20. doi: 10.14670/HH-28.405. Epub 2013 Feb 15. Review.


Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists.

Batie S, Lee JH, Jama RA, Browder DO, Montano LA, Huynh CC, Marcus LM, Tsosie DG, Mohammed Z, Trang V, Marshall PA, Jurutka PW, Wagner CE.

Bioorg Med Chem. 2013 Feb 1;21(3):693-702. doi: 10.1016/j.bmc.2012.11.033. Epub 2012 Dec 5.


Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes.

Meyer MB, Pike JW.

J Steroid Biochem Mol Biol. 2013 Jul;136:120-4. doi: 10.1016/j.jsbmb.2012.08.006. Epub 2012 Aug 25.


Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells.

Höbaus J, Fetahu ISh, Khorchide M, Manhardt T, Kallay E.

J Steroid Biochem Mol Biol. 2013 Jul;136:296-9. doi: 10.1016/j.jsbmb.2012.08.003. Epub 2012 Aug 20.

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