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Items: 1 to 20 of 108


Pharmacological Evaluation of TAK-828F, a Novel Orally Available RORγt Inverse Agonist, on Murine Colitis Model.

Igaki K, Nakamura Y, Komoike Y, Uga K, Shibata A, Ishimura Y, Yamasaki M, Tsukimi Y, Tsuchimori N.

Inflammation. 2018 Aug 18. doi: 10.1007/s10753-018-0875-7. [Epub ahead of print]


Targeting Inflammatory T Helper Cells via Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis.

Buchele V, Abendroth B, Büttner-Herold M, Vogler T, Rothamer J, Ghimire S, Ullrich E, Holler E, Neurath MF, Hildner K.

Front Immunol. 2018 May 25;9:1138. doi: 10.3389/fimmu.2018.01138. eCollection 2018.


Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.

Long Y, Li S, Qin J, Xie L, Gan L, Jie F, Wu Y, Li Y, Du Q.

Biomed Pharmacother. 2018 Sep;105:781-788. doi: 10.1016/j.biopha.2018.06.011. Epub 2018 Jun 15.


Soluble Mucosal Addressin Cell Adhesion Molecule 1 and Retinoic Acid are Potential Tools for Therapeutic Drug Monitoring in Patients with Inflammatory Bowel Disease Treated with Vedolizumab: A Proof of Concept Study.

Paul S, Williet N, Di Bernado T, Berger AE, Boschetti G, Filippi J, Del Tedesco E, Nancey S, Flourie B, Roblin X.

J Crohns Colitis. 2018 May 31. doi: 10.1093/ecco-jcc/jjy077. [Epub ahead of print]


Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice.

Engman C, Garciafigueroa Y, Phillips BE, Trucco M, Giannoukakis N.

Front Immunol. 2018 May 3;9:894. doi: 10.3389/fimmu.2018.00894. eCollection 2018.


Canonical Wnt Signaling in CD11c+ APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon.

Swafford D, Shanmugam A, Ranganathan P, Hussein MS, Koni PA, Prasad PD, Thangaraju M, Manicassamy S.

J Immunol. 2018 May 1;200(9):3259-3268. doi: 10.4049/jimmunol.1701086. Epub 2018 Mar 30.


The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis.

Peng ZW, Rothweiler S, Wei G, Ikenaga N, Liu SB, Sverdlov DY, Vaid KA, Longhi MS, Kuang M, Robson SC, Popov YV.

Hepatol Commun. 2017 Sep 26;1(9):957-972. doi: 10.1002/hep4.1084. eCollection 2017 Nov.


GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis.

Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein MS, Koni PA, Prasad PD, Kurago ZB, Thangaraju M, Ganapathy V, Manicassamy S.

J Immunol. 2018 Mar 1;200(5):1781-1789. doi: 10.4049/jimmunol.1700604. Epub 2018 Jan 31.


Pharmacological inhibitory profile of TAK-828F, a potent and selective orally available RORγt inverse agonist.

Shibata A, Uga K, Sato T, Sagara M, Igaki K, Nakamura Y, Ochida A, Kono M, Shirai J, Yamamoto S, Yamasaki M, Tsuchimori N.

Biochem Pharmacol. 2018 Apr;150:35-45. doi: 10.1016/j.bcp.2018.01.023. Epub 2018 Jan 31.


Lactobacillus brevis KB290 With Vitamin A Ameliorates Murine Intestinal Inflammation Associated With the Increase of CD11c+ Macrophage/CD103- Dendritic Cell Ratio.

Fuke N, Takagi T, Higashimura Y, Tsuji T, Umeda R, Mizushima K, Tanaka M, Suganuma H, Aizawa K, Yajima N, Naito Y.

Inflamm Bowel Dis. 2018 Jan 18;24(2):317-331. doi: 10.1093/ibd/izx003.


Dietary antioxidant micronutrients alter mucosal inflammatory risk in a murine model of genetic and microbial susceptibility.

Pierre JF, Hinterleitner R, Bouziat R, Hubert NA, Leone V, Miyoshi J, Jabri B, Chang EB.

J Nutr Biochem. 2018 Apr;54:95-104. doi: 10.1016/j.jnutbio.2017.12.002. Epub 2017 Dec 10.


Iguratimod ameliorates inflammatory responses by modulating the Th17/Treg paradigm in dextran sulphate sodium-induced murine colitis.

Jiang XP, Huang XL, Yang ZP, Wang SC, Xie W, Miao L, Tang L, Huang ZM.

Mol Immunol. 2018 Jan;93:9-19. doi: 10.1016/j.molimm.2017.10.008. Epub 2017 Nov 6.


Novel insights into microbiome in colitis and colorectal cancer.

Yang Y, Jobin C.

Curr Opin Gastroenterol. 2017 Nov;33(6):422-427. doi: 10.1097/MOG.0000000000000399. Review.


Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression.

Zaman TS, Arimochi H, Maruyama S, Ishifune C, Tsukumo SI, Kitamura A, Yasutomo K.

J Immunol. 2017 Sep 15;199(6):1989-1997. doi: 10.4049/jimmunol.1700645. Epub 2017 Aug 4.


Inflammation-associated DNA methylation patterns in epithelium of ulcerative colitis.

Barnicle A, Seoighe C, Greally JM, Golden A, Egan LJ.

Epigenetics. 2017 Aug;12(8):591-606. doi: 10.1080/15592294.2017.1334023. Epub 2017 May 30.


Cellular retinoic acid bioavailability in various pathologies and its therapeutic implication.

Osanai M.

Pathol Int. 2017 Jun;67(6):281-291. doi: 10.1111/pin.12532. Epub 2017 Apr 19. Review.


All-Trans Retinoic Acid Modulates TLR4/NF-κB Signaling Pathway Targeting TNF-α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer.

Rafa H, Benkhelifa S, AitYounes S, Saoula H, Belhadef S, Belkhelfa M, Boukercha A, Toumi R, Soufli I, Moralès O, de Launoit Y, Mahfouf H, Nakmouche M, Delhem N, Touil-Boukoffa C.

Mediators Inflamm. 2017;2017:7353252. doi: 10.1155/2017/7353252. Epub 2017 Mar 20.


IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes.

Luo M, Yeruva S, Liu Y, Chodisetti G, Riederer B, Menon MB, Tachibana K, Doi T, Seidler UE.

Front Physiol. 2017 Feb 7;8:61. doi: 10.3389/fphys.2017.00061. eCollection 2017.


Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced by Their Isotype.

Girard A, Jelicic K, Van Ryk D, Rochereau N, Cicala C, Arthos J, Noailly B, Genin C, Verrier B, Laurant S, Razanajaoana-Doll D, Pin JJ, Paul S.

J Acquir Immune Defic Syndr. 2017 May 1;75(1):118-127. doi: 10.1097/QAI.0000000000001307.


RNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer.

Zhu H, Xu WY, Hu Z, Zhang H, Shen Y, Lu S, Wei C, Wang ZG.

J Exp Clin Cancer Res. 2017 Jan 5;36(1):2. doi: 10.1186/s13046-016-0471-3.

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